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PENYAKIT TIDAK
BERJANGKIT (NCD)
Types of NCDs
• Cardiovascular disease (e.g.,
Coronary heart disease, Stroke)
Diabetes
Cancer
Chronic respiratory disease
•
•
•
Risk Factor: Definition
“An aspect of personal behavior or
lifestyle, an environmental exposure,
or a hereditary characteristic that is
associated with an increase
in the occurrence of a particular
disease, injury or other health
condition.”
Principles of Epidemiology, CDC, 2006
Modifiable Risk Factor
• A behavioral risk factor that can be reduced or
controlled by intervention, thereby reducing the
probability of disease.
• WHO has prioritized the following four:
I. Physical inactivity,
II. Tobacco use,
III.Alcohol use, and
IV.Unhealthy diets (increased fat and sodium, with low
fruit and vegetable intake).
Non-Modifiable Risk Factor
A risk factor that cannot be reduced or controlled
by intervention; for example:
•
•
•
•
Age,
Gender,
Race, and
Family history (genetics).
Common Risk Factors
Global Trends Causes of Deaths
Projected Deaths in 2015 and 2030
0
5
10
15
20
25
30
2004 2015 2030 2004 2015 2030 2004 2015 2030
Deaths(millions)
High income Middle income Low income
Other infectious
HIV, TB, malaria
Mat//peri/nutritional
CVDT
Cancers
Other NCDs
Intentional injuries
Other unintentional
Road traffic accidents
http://www.who.int/healthinfo/global_burden_disease/GBD_report_2004update_part2.pdf
NCD IN MALAYSIA
 Ancaman kesihatan baru
 Jumlah pesakit meningkat setiap tahun.
 10 penyebab utama penyakit negara
 60% ( ~ 35 juta) jumlah kematian di dunia
disumbang oleh NCD (WHO)
NHMS 2015 adults 18 years and above
 17.5% (3.5 m) have diabetes
 30.3% (6.1 m) have hypertension
 47.7% (9.6 m) have hypercholesterolemia
NCD RISK FACTORS
 Common, preventable risk factors underlie
most NCDs.
 These risk factors are a leading cause of the
death and disability burden in nearly all
countries, regardless of economic
development.
1.Tobacco Use
• Tobacco kills nearly 6 million people each year.
http://www.who.int/mediacentre/factsheets/fs339/en/index.html
MALAYSIA : PREVALENCE OF
SMOKING BY SEX (1996, 2006,
2011 & 2015)
%
• 1996 &2006 – adult 18 & above
Malaysia : Prevalence of smoking by states, ≥ 15 years (2015)
%
Tobacco Use: Health Effects
Mathers CD, Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Medicine, 2006,
3(11): e442.
Tobacco Use: Health Effects
(cont.)
Among smokers:
•
•
•
•
Cancer
Coronary heart disease
Diseases of the lungs
Peripheral vascular
disease
Stroke
Fetal complications and
stillbirth
•
•
• Second-hand smoke
causes:
• Heart disease, including
heart attack
• Lung cancer
2. UNHEALTHY DIET
Global Changes in Diet
http://www.pitt.edu/~super4/41011-42001/41171.pdf
• Most countries have increased overall daily
consumption of:
• Daily calories,
• Fat and meats, and
• Energy dense and nutrient-poor foods such
as:
‒ Starches
‒ Refined sugars
‒ Trans-fats
Unhealthy Diet: Health Effects
•
•
•
•
•
•
•
Coronary heart disease
Stroke
Cancer
Type 2 diabetes
Hypertension
Diseases of the liver and gallbladder
Obesity
3.PHYSICAL INACTIVITY
Global Changes in Physical Activity
• 31% of the world’s population does not get enough
physical activity.
• Many social and economic changes contribute to
this trend:
•
•
•
Aging populations,
Transportation, and
Communication technology.
1. http://www.cdc.gov/physicalactivity/everyone/guidelines/adults.html
2. http://www.sciencedirect.com/science/article/pii/S0140673612608988
Global Changes in Physical
Activity (cont.)
Lee IM, Shiroma EJ, Lobelo F, Puska P, Blair SN, Katzmarzyk PT; Lancet Physical Activity Series Working Group.
Effect of physical inactivity on major non-communicable diseases worldwide: an analysis of burden of disease and life
expectancy. Lancet. 2012 Jul 21;380(9838):219-29
Physical Activity: Health Effects
Reduces:
•  High blood
pressure
• Adverse lipid
profile
• Arthritis pain
Reduces risk of:
• Type 2 diabetes
• Certain cancers
• Heart attacks
• Stroke
• Falls
http://www.health.gov/paguidelines/factsheetprof.aspx
4.HARMFUL USE OF ALCOHOL
Harmful Use of Alcohol: Effects
Immediate effects:
• Diminished brain
function
•
•
•
Loss of body heat
Fetal damage
Risk for unintentional
injuries
•
•
Risk for violence
Coma and death
Long-term effects:
•
•
•
•
Liver diseases
Cancers
Hypertension
Gastrointestinal
disorders
• Neurological issues
• Psychiatric issues
Metabolic Risk Factors
http://www.who.int/nmh/events/2012/discussion_paper3.pdf
• “Metabolic" refers to the biochemical processes
involved in the body's normal functioning
Behaviors (modifiable risk factors) can lead to
metabolic/physiologic changes.
WHO has prioritized the following four metabolic
risk factors:
•
•
‒
‒
‒
‒
Raised blood pressure
Raised total cholesterol
Elevated glucose
Overweight and obesity
1.OBESITY
KADAR OBESITI DI SELURUH
DUNIA
17.7%
MALAYSIA
1.Puberty
2.Men above 30
3.Pregnancy
4.The freshman year of college
5.Injury
6.Depression
7.Menopause and peri-menopause
(Women in their 50’s )
LIFE STAGE: CRITICAL PERIODS FOR
WEIGHT GAIN
OBESITI
COMPLICATIONS OF
OBESITY
2.HIPERTENSI / TEKANAN DARAH
TINGGI
Overview of NCD’s and Risk Factors
Raised Blood Pressure
Measurement Normal Pre-Hypertensive Hypertensive
Systolic
mmHg
Diastolic
mmHg
<120 120-139 140+
<80 80-89 90+
36.4
27.9
32.8
34.1
29.9
28.4
42.9
41.1
28.7 29.1
40.5
27.1
22.5
27.4
38.327.5
33.8
25.8
32.5
28.5
29.8
36.4
35.4
25.5
26.286.9 26.8
37.3
33.8
24.1
20.0
15.0
10.0
5.0
0.0
25.0
30.0
35.0
40.0
45.0
Prevalence(%)
MALAYSIA : PREVALENCE OF HYPERTENSION BY
STATE,
≥18 YEARS (2011 & 2015)
2011 2015
FAKTOR RISIKO HIPERTENSI
Raised Blood Pressure: Health Effects
•
•
•
Leading risk factor for stroke
Major risk factor for coronary heart disease
Risk of CVD doubles for
each increment of 20/10 mmHg of blood pressure
Other complications of raised blood pressure:•
‒ Heart failure
‒ Peripheral vascular disease
‒ Renal impairment
‒ Retinal hemorrhage
‒ Visual impairment
Hypertension and Excessive
Sodium Intake
• Sodium, through hypertension, is a major cause of
cardiovascular disease deaths and disability.
• About 10% of cardiovascular disease is caused by
excess sodium intake.
• 8.5 million deaths could be prevented over 10 years
if sodium intake were reduced by 15%.
Sources of Sodium
• People are unaware of how much dietary sodium
they are eating.
• In the U.S. 75% of sodium consumed comes from
processed and restaurant foods.
• In China and Japan, 75% of sodium consumed
comes from cooking with high sodium products.
Recommendations and Actual
Intakes WHO/PAHO
• Recommendations
• A population salt intake of less than 5 grams or
approximately 2,000 milligrams of sodium, per person per
day is recommended to reach national targets or in their
absence. This level was recommended for the prevention
of cardiovascular diseases.
• Actual Intake
• Latest global estimates show that average sodium intake
varies from 2,000 to 7,200 milligrams of sodium per
person per day.
3.DIABETES MELLITUS
Diabetes : keadaan di mana paras
gula dalam darah adalah tinggi dari
normal.
Bila paras gula dalam badan
meningkat:
 Merosakkan sel yang memerlukan
glukosa untuk bahan bakar dan
Diabetes: Burden of Disease
1. http://www.who.int/mediacentre/factsheets/en/
2.http://www.idf.org/regions
• 347 million people worldwide have diabetes.
• In 2004, an estimated 3.4 million people died from consequences of
high blood sugar.
• Healthy diet, regular physical activity, maintaining a normal body
weight and avoiding tobacco use can prevent or delay the onset of
type 2 diabetes.
GOLONGAN RISIKO TINGGI UNTUK
MENDAPAT DIABETES
Berat badan berlebihan atau
obesiti.
Semakin berat >> semakin
tinggi risiko diabetes.
Faktor pemakanan
Lebih makanan bergoreng/lemak
tinggi dan kurang pengambilan
makanan berserat
11.6
15.2
17.5
7.2
8.3
47.50
8.0
9.2
4.2
4.9 4.7
20.0
18.0
16.0
14.0
12.0
10.0
8.0
6.0
4.0
2.0
0.0
NHMS 2011
Prevalence(%)
NHMS III (2006)
Total diabetes Known Undiagnosed
NHMS 2015
IFG
MALAYSIA : PREVALENCE OF DIABETES,
≥18 YEARS
(2006, 2011, 2015)
NHMS II
(1996)
NHMS III
(2006)
NHMS 2011 NHMS 2015
Age group S30 years S18 years S18 years Est. Population ≥18 years
Prevalence 8.3% 11.6% 15.2% 2,622,284 17.5%
Known diabetes 6.5% 7.0% 7.2% 1,247,366 8.3%
Undiagnosed 1.8% 4.5% 8.0% 1,374,918 9.2%
IGT* / IFG** 4.3% * 4.2% ** 4.9% ** 481,477
19.8
25.4
18.5
16.7
19.3
14.8
18.1
19.4
20.6
15.5
18.6
14.2
14.8
17.4
19.2
0.0
5.0
10.0
15.0
20.0
25.0
30.0
Prevalence(%)
PREVALENCE OF DIABETES, ≥18
YEARS,
BY STATES (2006, 2011 & 2015)
NHMS 2015NHMS III (2006) NHMS 2011
Berita baik
adalah jika
seorang DM
dapat
mengawal
diabetes
dengan baik,
ia membantu
mengelakkan
atau
melambatkan
komplikasi
22.8% (5 m) currently smoked tobacco (
NHMS 2015)
Pencegahan COPD
Berhenti Merokok - Terapi
gentian nikotin/pengurangan
keinginan merokok.
NCD BOLEH DICEGAH
Hampir 80% penyakit jantung, stroke dan diabetes
jenis II boleh di cegah daripada berlaku
Dengan menyingkirkan faktor risiko NCD
Penggunaan tembakau, pemakanan tidak sihat, tidak
aktif fizikal dan pengambilan alcohol.
Penyakit NCD di Malaysia
Penyakit NCD di Malaysia

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Penyakit NCD di Malaysia

  • 2.
  • 3. Types of NCDs • Cardiovascular disease (e.g., Coronary heart disease, Stroke) Diabetes Cancer Chronic respiratory disease • • •
  • 4. Risk Factor: Definition “An aspect of personal behavior or lifestyle, an environmental exposure, or a hereditary characteristic that is associated with an increase in the occurrence of a particular disease, injury or other health condition.” Principles of Epidemiology, CDC, 2006
  • 5. Modifiable Risk Factor • A behavioral risk factor that can be reduced or controlled by intervention, thereby reducing the probability of disease. • WHO has prioritized the following four: I. Physical inactivity, II. Tobacco use, III.Alcohol use, and IV.Unhealthy diets (increased fat and sodium, with low fruit and vegetable intake).
  • 6. Non-Modifiable Risk Factor A risk factor that cannot be reduced or controlled by intervention; for example: • • • • Age, Gender, Race, and Family history (genetics).
  • 8.
  • 9. Global Trends Causes of Deaths Projected Deaths in 2015 and 2030 0 5 10 15 20 25 30 2004 2015 2030 2004 2015 2030 2004 2015 2030 Deaths(millions) High income Middle income Low income Other infectious HIV, TB, malaria Mat//peri/nutritional CVDT Cancers Other NCDs Intentional injuries Other unintentional Road traffic accidents http://www.who.int/healthinfo/global_burden_disease/GBD_report_2004update_part2.pdf
  • 10. NCD IN MALAYSIA  Ancaman kesihatan baru  Jumlah pesakit meningkat setiap tahun.  10 penyebab utama penyakit negara  60% ( ~ 35 juta) jumlah kematian di dunia disumbang oleh NCD (WHO) NHMS 2015 adults 18 years and above  17.5% (3.5 m) have diabetes  30.3% (6.1 m) have hypertension  47.7% (9.6 m) have hypercholesterolemia
  • 11. NCD RISK FACTORS  Common, preventable risk factors underlie most NCDs.  These risk factors are a leading cause of the death and disability burden in nearly all countries, regardless of economic development.
  • 12. 1.Tobacco Use • Tobacco kills nearly 6 million people each year. http://www.who.int/mediacentre/factsheets/fs339/en/index.html
  • 13. MALAYSIA : PREVALENCE OF SMOKING BY SEX (1996, 2006, 2011 & 2015) % • 1996 &2006 – adult 18 & above
  • 14. Malaysia : Prevalence of smoking by states, ≥ 15 years (2015) %
  • 15. Tobacco Use: Health Effects Mathers CD, Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Medicine, 2006, 3(11): e442.
  • 16. Tobacco Use: Health Effects (cont.) Among smokers: • • • • Cancer Coronary heart disease Diseases of the lungs Peripheral vascular disease Stroke Fetal complications and stillbirth • • • Second-hand smoke causes: • Heart disease, including heart attack • Lung cancer
  • 18. Global Changes in Diet http://www.pitt.edu/~super4/41011-42001/41171.pdf • Most countries have increased overall daily consumption of: • Daily calories, • Fat and meats, and • Energy dense and nutrient-poor foods such as: ‒ Starches ‒ Refined sugars ‒ Trans-fats
  • 19. Unhealthy Diet: Health Effects • • • • • • • Coronary heart disease Stroke Cancer Type 2 diabetes Hypertension Diseases of the liver and gallbladder Obesity
  • 21. Global Changes in Physical Activity • 31% of the world’s population does not get enough physical activity. • Many social and economic changes contribute to this trend: • • • Aging populations, Transportation, and Communication technology. 1. http://www.cdc.gov/physicalactivity/everyone/guidelines/adults.html 2. http://www.sciencedirect.com/science/article/pii/S0140673612608988
  • 22. Global Changes in Physical Activity (cont.) Lee IM, Shiroma EJ, Lobelo F, Puska P, Blair SN, Katzmarzyk PT; Lancet Physical Activity Series Working Group. Effect of physical inactivity on major non-communicable diseases worldwide: an analysis of burden of disease and life expectancy. Lancet. 2012 Jul 21;380(9838):219-29
  • 23. Physical Activity: Health Effects Reduces: •  High blood pressure • Adverse lipid profile • Arthritis pain Reduces risk of: • Type 2 diabetes • Certain cancers • Heart attacks • Stroke • Falls http://www.health.gov/paguidelines/factsheetprof.aspx
  • 24. 4.HARMFUL USE OF ALCOHOL
  • 25. Harmful Use of Alcohol: Effects Immediate effects: • Diminished brain function • • • Loss of body heat Fetal damage Risk for unintentional injuries • • Risk for violence Coma and death Long-term effects: • • • • Liver diseases Cancers Hypertension Gastrointestinal disorders • Neurological issues • Psychiatric issues
  • 26. Metabolic Risk Factors http://www.who.int/nmh/events/2012/discussion_paper3.pdf • “Metabolic" refers to the biochemical processes involved in the body's normal functioning Behaviors (modifiable risk factors) can lead to metabolic/physiologic changes. WHO has prioritized the following four metabolic risk factors: • • ‒ ‒ ‒ ‒ Raised blood pressure Raised total cholesterol Elevated glucose Overweight and obesity
  • 28. KADAR OBESITI DI SELURUH DUNIA 17.7% MALAYSIA
  • 29.
  • 30. 1.Puberty 2.Men above 30 3.Pregnancy 4.The freshman year of college 5.Injury 6.Depression 7.Menopause and peri-menopause (Women in their 50’s ) LIFE STAGE: CRITICAL PERIODS FOR WEIGHT GAIN
  • 32.
  • 33.
  • 35.
  • 36.
  • 37. 2.HIPERTENSI / TEKANAN DARAH TINGGI
  • 38. Overview of NCD’s and Risk Factors Raised Blood Pressure Measurement Normal Pre-Hypertensive Hypertensive Systolic mmHg Diastolic mmHg <120 120-139 140+ <80 80-89 90+
  • 39.
  • 42.
  • 43.
  • 44. Raised Blood Pressure: Health Effects • • • Leading risk factor for stroke Major risk factor for coronary heart disease Risk of CVD doubles for each increment of 20/10 mmHg of blood pressure Other complications of raised blood pressure:• ‒ Heart failure ‒ Peripheral vascular disease ‒ Renal impairment ‒ Retinal hemorrhage ‒ Visual impairment
  • 45. Hypertension and Excessive Sodium Intake • Sodium, through hypertension, is a major cause of cardiovascular disease deaths and disability. • About 10% of cardiovascular disease is caused by excess sodium intake. • 8.5 million deaths could be prevented over 10 years if sodium intake were reduced by 15%.
  • 46. Sources of Sodium • People are unaware of how much dietary sodium they are eating. • In the U.S. 75% of sodium consumed comes from processed and restaurant foods. • In China and Japan, 75% of sodium consumed comes from cooking with high sodium products.
  • 47. Recommendations and Actual Intakes WHO/PAHO • Recommendations • A population salt intake of less than 5 grams or approximately 2,000 milligrams of sodium, per person per day is recommended to reach national targets or in their absence. This level was recommended for the prevention of cardiovascular diseases. • Actual Intake • Latest global estimates show that average sodium intake varies from 2,000 to 7,200 milligrams of sodium per person per day.
  • 48.
  • 49.
  • 50.
  • 51.
  • 52. 3.DIABETES MELLITUS Diabetes : keadaan di mana paras gula dalam darah adalah tinggi dari normal. Bila paras gula dalam badan meningkat:  Merosakkan sel yang memerlukan glukosa untuk bahan bakar dan
  • 53.
  • 54.
  • 55. Diabetes: Burden of Disease 1. http://www.who.int/mediacentre/factsheets/en/ 2.http://www.idf.org/regions • 347 million people worldwide have diabetes. • In 2004, an estimated 3.4 million people died from consequences of high blood sugar. • Healthy diet, regular physical activity, maintaining a normal body weight and avoiding tobacco use can prevent or delay the onset of type 2 diabetes.
  • 56. GOLONGAN RISIKO TINGGI UNTUK MENDAPAT DIABETES Berat badan berlebihan atau obesiti. Semakin berat >> semakin tinggi risiko diabetes. Faktor pemakanan Lebih makanan bergoreng/lemak tinggi dan kurang pengambilan makanan berserat
  • 57. 11.6 15.2 17.5 7.2 8.3 47.50 8.0 9.2 4.2 4.9 4.7 20.0 18.0 16.0 14.0 12.0 10.0 8.0 6.0 4.0 2.0 0.0 NHMS 2011 Prevalence(%) NHMS III (2006) Total diabetes Known Undiagnosed NHMS 2015 IFG MALAYSIA : PREVALENCE OF DIABETES, ≥18 YEARS (2006, 2011, 2015) NHMS II (1996) NHMS III (2006) NHMS 2011 NHMS 2015 Age group S30 years S18 years S18 years Est. Population ≥18 years Prevalence 8.3% 11.6% 15.2% 2,622,284 17.5% Known diabetes 6.5% 7.0% 7.2% 1,247,366 8.3% Undiagnosed 1.8% 4.5% 8.0% 1,374,918 9.2% IGT* / IFG** 4.3% * 4.2% ** 4.9% ** 481,477
  • 59. Berita baik adalah jika seorang DM dapat mengawal diabetes dengan baik, ia membantu mengelakkan atau melambatkan komplikasi
  • 60.
  • 61.
  • 62.
  • 63. 22.8% (5 m) currently smoked tobacco ( NHMS 2015)
  • 64.
  • 65. Pencegahan COPD Berhenti Merokok - Terapi gentian nikotin/pengurangan keinginan merokok.
  • 66.
  • 67.
  • 68. NCD BOLEH DICEGAH Hampir 80% penyakit jantung, stroke dan diabetes jenis II boleh di cegah daripada berlaku Dengan menyingkirkan faktor risiko NCD Penggunaan tembakau, pemakanan tidak sihat, tidak aktif fizikal dan pengambilan alcohol.