30. REFER TO LIVER CENTER
INR >3.0 at 48h or >4.5 any time
oliguria or Cr >200 μmol/L
persistent acidosis (pH < 7.3) or arterial
lactate >3 mmol/L
SBP <80 mmHg, despite resus
hypoglycaemia
severe thrombocytopenia
encephalopathy
31. Role of liver transplantation
for paracetamol toxicity is
controversial
32. OTHER SCENARIOS:
Unknown time of ingestion!
Staggered ingestions!
Repeated supra-therapeutic
ingestion (RSI)!
Modified release tablets!
Liquid and IV formulations!