1. Bioinformatics

2.  3D structure of Collagen alpha 1
 Alignment
 Guid tree
 Jalview
 Fasta
 Protein blast
 Phylogenetic tree
 Map viewer
 Conclusion
 Application

3. SUB-TOPIC:- Comparative study of collagen
alpha 1 between homo sapiens and macaca
mulatta

6.  >tr|D3DSM7|D3DSM7_HUMAN Collagen, type VI, alpha 1, isoform CRA_a OS=Homo
sapiens GN=COL6A1 PE=4 SV=1
MRAARALLPLLLQACWTAAQDEPETPRAVAFQDCPVDLFFVLDTSESVALRLKPYGALVD
KVKSFTKRFIDNLRDRYYRCDRNLVWNAGALHYSDEVEIIQGLTRMPGGRDALKSSVDAV
KYFGKGTYTDCAIKKGLEQLLVGGSHLKENKYLIVVTDGHPLEGYKEPCGGLEDAVNEAK
HLGVKVFSVAITPDHLEPRLSIIATDHTYRRNFTAADWGQSRDAEEAISQTIDTIVDMIK
NNVEQVCCSFECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGY
QGM
KGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGP
PGP
KGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPG
PDGA
PGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKG
YRGD
EGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGIN
GTK
GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPDECEILD
II
MKMCCEMQVRPHRPPVRAGQLREHWPAELRDCQGLRRQGHRPAEPGRAGQVRARAV
VRGC
GAVQPQPDAGAREPAQPQHPERAGAQGSHQEPAVDGGRHLHGGGPAVHAGPAAAAQ
PEQP HRPGHH

7.  >tr|I0FP93|I0FP93_MACMU Collagen alpha-1(VI) chain OS=Macaca mulatta GN=COL6A1 PE=2
SV=1 MRAARALLPLLLQACWTAGQDEPETPRAVAFQDCPVDLFFVLDTSESVALRLKPYGALVD
KVKSFTKRFIDNLRDRYYRCDRNLVWNAGALHYSDDVEIIQGLTRMPGDRDTLKSRVDAI
KYFGKGTYTDCAIKKGLEQLLVGGSHLKENKYLIVVTDGHPLEGYKEPCGGLEDAVNEAK
HLGVKVFSVAITPDHLEPRLSIIATDHTYRRNFTAADWGQSRDAEEVISQTIDTIVDMIK
NNVEQVCCSFECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGM
KGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGP
KGDPGAFGLKGEKGEPGADGEAGRPGSSGPPGDEGEPGEPGPPGEKGEAGDEGNPGPDGA
PGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD
EGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPPGNGTEGFPGFPGYPGNRGPPGINGTK
GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHPGPPGPDECEILDII
MKMCSCCECKCGPIDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYA
GVVQYSHSQMQEHVSLRSPSIRNVQELKEAIKNLQWMAGGTFTGEALQYTRDQLLPPSPN
NRIALVITDGRSDTQRDTTPLNVLCSPGVQVVSVGIKDVFDFVPGSDQLNVISCQGLAPS
QGRAGLSLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPIPFSSPADITILLDSSASV
GSHNFDTTKRFAKRLAERFLMAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTAL
ASAVDAMDFINDATDVNDALGYVTRFYREASSGAAKKRLLLFSDGNSQGATPAAIEKAVQ
EAQRAGIEIFVVVVGRQVNEPHIRVLVTGKTAEYDVAYGERHLFRVPSYQALLRGVFHQT
VSRKVALG

14.  The rhesus(macaca mulatta) genome shares
about 93 percent of its sequence with the
human genome.

16.  The rhesus is widely recognized as the best
animal model for human immunodeficiency
virus (HIV) infection.
 It also serves as a valuable model for
studying other human infectious diseases and
for vaccine research.
 The rhesus macaque genome sequence
enhances essential research in neuroscience,
behavioral biology, reproductive physiology,
endocrinology and cardiovascular studies.

17.  https://www.google.co.in
 http://www.ncbi.nlm.nih.gov
 http://www.ncbi.nlm.nih.gov/Structure/MMD
B/mmdb.shtml
 http://www.uniprot.org/
 http://blast.ncbi.nlm.nih.gov/Blast.cgi