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REFLEX
CONTENTS:
 DEFINITION
 REFLEX ARC
 TYPES/CLASSIFICATION OF
REFLEXES
 STRETCH REFLEX
 MUSCLE SPINDLE
 PROPERTIES OF REFLEXES26-Jan-16 1Dr. Ashok Solanki
26-Jan-16 Dr. Ashok Solanki 2
26-Jan-16 Dr. Ashok Solanki 3
Nerve pathways
Ascending Tracts
Tract Signal function
Dorsal columns
Vibration, tactile sensation, conscious
proprioception
Spinocerebeller Proprioception
Spinothalamic (lateral and
anterior)
Pain, temperature, itch (lateral), crude
touch (anterior)
Spinoreticular Pain
Spinomesencephalic Pain
Spino-cervico-thalamic Pain (touch?)
Spinohypothalamic Pain
Structure of spinal cord
26-Jan-16 Dr. Ashok Solanki 5
 Fetal 3rd month: ends at
coccyx
 Birth: ends at L3
 Adult position at approx L1-2
during childhood
 End: conus medullaris
 This tapers into filum terminale
of connective tissue, tethered
to coccyx
 Spinal cord segments are
superior to where their
corresponding spinal nerves
emerge through intervetebral
foramina (see also fig 17.5, p
288)
 Denticulate ligaments: lateral
shelves of pia mater anchoring
to dura (meninges: more later)
Spinal cord
http://www.apparelyzed.com/spinalcord.html
Spinal nerves continued
 Divided based on vertebral locations
 8 cervical
 12 thoracic
 5 lumbar
 5 sacral
 1 coccygeal
 Cauda equina (“horse’s tail”): collection of nerve
roots at inferior end of vertebral canal
Classified as
According to centre IN THE SPINAL CORD-
seg, inter, supra.
According to function-
flexor, extensor, postural R.
Clinically-
supreficial, deep, visceral
No. of synapse involved.
Mono and polysynaptic
According to origin–
spinal cord, brain stem, cortical etc.
Conditional and unconditional – since birth
 Rapid, stereotyped, invountary response to a sensory stimuli consciouslly or unconsciouslly.
826-Jan-16 Dr. Ashok Solanki
CLASSIFICATION
 CONDITIONED (ACQUIRED)/
UNCONDITIONED(SINCE BIRTH)
 CEREBELLER, CORTICAL, MIDBRAIN,
SPINAL
 SOMATIC:FLEXOR , EXTENSOR
VISCERAL: AUTONOMIC
 MONOSYNAPTIC , POLYSYNAPTIC
 SUPERFICIAL, DEEP, VISCERAL,
PATHOLOGICAL
 SEGMENTAL, INTERSEGMENTAL,
SUPRASEGMENTAL
26-Jan-16 9Dr. Ashok Solanki
26-Jan-16 Dr. Ashok Solanki 10
Dr. Ashok Solanki
Functions or reflex action
 Maintain the homeostasis- b.p regulation,
heart rate, digestive , autonomic reflexes
 Automatic actions
 Balance and posture
 Reflex maintining the movements -eyes
1226-Jan-16 Dr. Ashok Solanki
REFLEX ARC
 ANATOMICAL NERVOUS PATHWAY OF
REFLEX IS CALLED REFLEX ARC.
RECEPTOR
SENSORY / AFFERENT NERVE
CENTER
EFFERENT / MOTOR NERVE
EFFECTOR ORGAN
* BELL-MAGENDIE LAW: DORSAL ROOTS ARE
SENSORY & VENTRAL ROOTS ARE MOTOR.
26-Jan-16 13Dr. Ashok Solanki
SUPERFICIAL REFLEXES
 CORNEAL AND CONJUNCTIVAL
REFLEX
 PHARYNGEAL REFLEX
 PALATAL REFLEX
 ABDOMINAL RELEX
 PLANTAR REFLEX: Scratch over the
outer edge of sole cause plantar flexion
and adduction of all toes and dorsiflexion
and inversion of foot.( L5,S1)
 ANAL REFLEX26-Jan-16 14Dr. Ashok Solanki
DEEP REFLEXES
 JAW JERK: 5TH CRANIAL NV NUCLEI
 BICEPS JERK: C5,6
 TRICEPS JERK: C6,7
 SUPINATOR JERK: C5,6
 KNEE JERK: L2,3,4
 ANKLE JERK: S1,2
26-Jan-16 15Dr. Ashok Solanki
Reflex Arc
 Specific nerve impulse pathway
 5 components of reflex arc
 receptor
 sensory neuron
 integrating center
 motor neuron
 effector
Dr. Ashok Solanki 1626-Jan-16
PROPERTIES
 ONE WAY CONDUCTION
 SUMMATION: SPATIAL, TEMPORAL
 OCCLUSION
 SUBLIMINAL FRINGE
 RECRUITMENT
 AFTERDISCHARGE
 REBOUND PHENOMENON
 FATIGUE
 RECIPROCAL INNERVATION AND
RECIPROCAL INHIBITION
26-Jan-16 17Dr. Ashok Solanki
Flexor (withdrawal) Reflex
 Step on tack (pain fibers send
signal to spinal cord
 Interneurons branch to different
spinal cord segments
 Motor fibers in several
segments are activated
 More than one muscle group
activated to lift foot off of tack
Dr. Ashok Solanki 1826-Jan-16
Crossed Extensor Reflex
 Lifting left foot requires
extension of right leg to
maintain one’s balance
 Pain signals cross to opposite
spinal cord
 Contralateral extensor muscles
are stimulated by interneurons
to hold up the body weight
 Reciprocal innervation - when
extensors contract flexors
relax, etc
Dr. Ashok Solanki 1926-Jan-16
Clinical Considerations
 Checking a patient’s reflexes may help
to detect disorders/injury
 Plantar flexion reflex -- stroke the lateral
margin of the sole
 normal response is curling under the toes
 abnormal response or response of children
under 18 months is called Babinski sign
(upward fanning of toes due to incomplete
myelination in child)
Dr. Ashok Solanki 2026-Jan-16
Inverse stretch reflex
 Golgi tendon organ- 2 to 15 in each
muscle.
 Responds to tension and not the length
 The Golgi tendon reflex is a protective
reflex
 rise in tension is sensed by the Golgi
tendon a which stimulates the I-
b stimulates the I-b afferents
 stimulate the inhibitory interneurons
 inhibit the α-motoneuron discharge to 2126-Jan-16 Dr. Ashok Solanki
INVERSE STRETCH REFLEX/
AUTOGENIC INHIBITION
 WHEN A MUSCLE IS STRETCHED, IT
CONTRACTS BUT IF THE STRETCH IS
MAINTAINED (CONTINUED), THE
MUSCLE RELAXES.
26-Jan-16 22Dr. Ashok Solanki
UMN lesions
•weakness, paralysis
•spasticity
• tendon reflexes
•+ Babinski sign
•little,if any,muscle
atrophy
•no fasiculation
LMN lesions
•weakness, paralysis
•flaccidity, hypotonia
•Hypo- /no tendon
reflex
• - Babinski sign
•muscle atrophy
•fasiculation of
involved muscle
26-Jan-16 23Dr. Ashok Solanki
VISCERAL REFLEXES
 PUPILLARY REFLEXES:
DIRECT LIGHT REFLEX
INDIRECT OR CONSENSUAL LIGHT REFLEX
 ACCOMODATION REFLEX: CONSTRICTION
OF PUPIL, CONVERGENCE OF EYE BALLS,
INCREASE IN ANTERIOR CURVATURE OF
LENS
 CILIOSPINAL REFLEX: STIMULATION OF
SKIN IN NECK –DILATATION OF PUPILS
 OCULOCARDIAC REFLEX: PRESSURE OVER
EYEBALLS - BRADYCARDIA
26-Jan-16 24Dr. Ashok Solanki
PATHOLOGICAL REFLEXES
 BABINSKI’S SIGN +
Dorsiflexion of great toe and fanning of
other toes.
 CLONUS
 PENDULAR MOVEMENTS
26-Jan-16 25Dr. Ashok Solanki
26-Jan-16 26Dr. Ashok Solanki
26-Jan-16 27Dr. Ashok Solanki
26-Jan-16 28Dr. Ashok Solanki
Flexor reflex (Withdrawal, "hot stove")1. receptors sense
pain
2. sensory impulse to
spinal cord
3. synapse to
association neuron,
synapse to motor
neurons
 polysynaptic
4. motor neurons to
flexor muscles to
5. withdraw offended
body part from
stimulus
26-Jan-16 Dr. Ashok Solanki 29
26-Jan-16 30Dr. Ashok Solanki
Spinal reflexes
Static stretch reflex- maintain the tone
Maintain constant degree of muscle
contraction (Tone)
Continuous static receptor signal →
transmitted via both primary and
secondary neurons → S.C → continuous
command by static gamma motor
neurons → Tone.
Normal tone is due to continuous dischrge
26-Jan-16 31Dr. Ashok Solanki
Stretch reflex 2 types
-Response that is transmitted:
Dynemic:
-when there is change in the length of the spindle
receptor (stretching of the sensory receptor area of the
muscle spindle by stretching of the muscle spindle or the
whole muscle). Detect Change in length.
-transmitted by the primary fiber Aα type
Static
continuous information about the length of the muscle
(not the change in length).
transmitted by both the primary Aα and secondary (Aβ
and Aγ)
26-Jan-16 32Dr. Ashok Solanki
APPLIED:
Decreased (hypoactive) stretch reflex:
Destruction of sensory or motor nerve to the
muscle
Stimulation of inhibitory areas in brain
Inhibition of facilitatory areas in the brain
Hypothyroidism
26-Jan-16 33Dr. Ashok Solanki
Importance or use of stretch
reflex:
 1. Tone maintenance
 2. Maintenance of posture
 3. Control of voluntary movements
26-Jan-16 34Dr. Ashok Solanki
What are the components of reflex
action?
 Components of reflex
forms
reflex arc involving
1. receptor- sensory organ
2. afferent neuron-
3. centre
4. efferent neuron
5. effector organ
3526-Jan-16 Dr. Ashok Solanki
Reflex arc
 Diagram showing complete reflex arc
3626-Jan-16 Dr. Ashok Solanki
Dr. Ashok Solanki 3726-Jan-16
Dr. Ashok Solanki 3826-Jan-16
2. 5 Essential Components
of the Reflex Arc
39
Dr. Ashok Solanki
Stimulus at distal
end of neuron
Skin Spinal cord
(in cross section)
Interneuron
Receptor
Effector
Sensory neuron
Motor neuron
Integration
center
(a)
26-Jan-16 Dr. Ashok Solanki
26-Jan-16 40Dr. Ashok Solanki
26-Jan-16 41Dr. Ashok Solanki

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reflexes, clasifications, and functions.

  • 1. REFLEX CONTENTS:  DEFINITION  REFLEX ARC  TYPES/CLASSIFICATION OF REFLEXES  STRETCH REFLEX  MUSCLE SPINDLE  PROPERTIES OF REFLEXES26-Jan-16 1Dr. Ashok Solanki
  • 4. Nerve pathways Ascending Tracts Tract Signal function Dorsal columns Vibration, tactile sensation, conscious proprioception Spinocerebeller Proprioception Spinothalamic (lateral and anterior) Pain, temperature, itch (lateral), crude touch (anterior) Spinoreticular Pain Spinomesencephalic Pain Spino-cervico-thalamic Pain (touch?) Spinohypothalamic Pain
  • 5. Structure of spinal cord 26-Jan-16 Dr. Ashok Solanki 5
  • 6.  Fetal 3rd month: ends at coccyx  Birth: ends at L3  Adult position at approx L1-2 during childhood  End: conus medullaris  This tapers into filum terminale of connective tissue, tethered to coccyx  Spinal cord segments are superior to where their corresponding spinal nerves emerge through intervetebral foramina (see also fig 17.5, p 288)  Denticulate ligaments: lateral shelves of pia mater anchoring to dura (meninges: more later) Spinal cord http://www.apparelyzed.com/spinalcord.html
  • 7. Spinal nerves continued  Divided based on vertebral locations  8 cervical  12 thoracic  5 lumbar  5 sacral  1 coccygeal  Cauda equina (“horse’s tail”): collection of nerve roots at inferior end of vertebral canal
  • 8. Classified as According to centre IN THE SPINAL CORD- seg, inter, supra. According to function- flexor, extensor, postural R. Clinically- supreficial, deep, visceral No. of synapse involved. Mono and polysynaptic According to origin– spinal cord, brain stem, cortical etc. Conditional and unconditional – since birth  Rapid, stereotyped, invountary response to a sensory stimuli consciouslly or unconsciouslly. 826-Jan-16 Dr. Ashok Solanki
  • 9. CLASSIFICATION  CONDITIONED (ACQUIRED)/ UNCONDITIONED(SINCE BIRTH)  CEREBELLER, CORTICAL, MIDBRAIN, SPINAL  SOMATIC:FLEXOR , EXTENSOR VISCERAL: AUTONOMIC  MONOSYNAPTIC , POLYSYNAPTIC  SUPERFICIAL, DEEP, VISCERAL, PATHOLOGICAL  SEGMENTAL, INTERSEGMENTAL, SUPRASEGMENTAL 26-Jan-16 9Dr. Ashok Solanki
  • 10. 26-Jan-16 Dr. Ashok Solanki 10
  • 12. Functions or reflex action  Maintain the homeostasis- b.p regulation, heart rate, digestive , autonomic reflexes  Automatic actions  Balance and posture  Reflex maintining the movements -eyes 1226-Jan-16 Dr. Ashok Solanki
  • 13. REFLEX ARC  ANATOMICAL NERVOUS PATHWAY OF REFLEX IS CALLED REFLEX ARC. RECEPTOR SENSORY / AFFERENT NERVE CENTER EFFERENT / MOTOR NERVE EFFECTOR ORGAN * BELL-MAGENDIE LAW: DORSAL ROOTS ARE SENSORY & VENTRAL ROOTS ARE MOTOR. 26-Jan-16 13Dr. Ashok Solanki
  • 14. SUPERFICIAL REFLEXES  CORNEAL AND CONJUNCTIVAL REFLEX  PHARYNGEAL REFLEX  PALATAL REFLEX  ABDOMINAL RELEX  PLANTAR REFLEX: Scratch over the outer edge of sole cause plantar flexion and adduction of all toes and dorsiflexion and inversion of foot.( L5,S1)  ANAL REFLEX26-Jan-16 14Dr. Ashok Solanki
  • 15. DEEP REFLEXES  JAW JERK: 5TH CRANIAL NV NUCLEI  BICEPS JERK: C5,6  TRICEPS JERK: C6,7  SUPINATOR JERK: C5,6  KNEE JERK: L2,3,4  ANKLE JERK: S1,2 26-Jan-16 15Dr. Ashok Solanki
  • 16. Reflex Arc  Specific nerve impulse pathway  5 components of reflex arc  receptor  sensory neuron  integrating center  motor neuron  effector Dr. Ashok Solanki 1626-Jan-16
  • 17. PROPERTIES  ONE WAY CONDUCTION  SUMMATION: SPATIAL, TEMPORAL  OCCLUSION  SUBLIMINAL FRINGE  RECRUITMENT  AFTERDISCHARGE  REBOUND PHENOMENON  FATIGUE  RECIPROCAL INNERVATION AND RECIPROCAL INHIBITION 26-Jan-16 17Dr. Ashok Solanki
  • 18. Flexor (withdrawal) Reflex  Step on tack (pain fibers send signal to spinal cord  Interneurons branch to different spinal cord segments  Motor fibers in several segments are activated  More than one muscle group activated to lift foot off of tack Dr. Ashok Solanki 1826-Jan-16
  • 19. Crossed Extensor Reflex  Lifting left foot requires extension of right leg to maintain one’s balance  Pain signals cross to opposite spinal cord  Contralateral extensor muscles are stimulated by interneurons to hold up the body weight  Reciprocal innervation - when extensors contract flexors relax, etc Dr. Ashok Solanki 1926-Jan-16
  • 20. Clinical Considerations  Checking a patient’s reflexes may help to detect disorders/injury  Plantar flexion reflex -- stroke the lateral margin of the sole  normal response is curling under the toes  abnormal response or response of children under 18 months is called Babinski sign (upward fanning of toes due to incomplete myelination in child) Dr. Ashok Solanki 2026-Jan-16
  • 21. Inverse stretch reflex  Golgi tendon organ- 2 to 15 in each muscle.  Responds to tension and not the length  The Golgi tendon reflex is a protective reflex  rise in tension is sensed by the Golgi tendon a which stimulates the I- b stimulates the I-b afferents  stimulate the inhibitory interneurons  inhibit the α-motoneuron discharge to 2126-Jan-16 Dr. Ashok Solanki
  • 22. INVERSE STRETCH REFLEX/ AUTOGENIC INHIBITION  WHEN A MUSCLE IS STRETCHED, IT CONTRACTS BUT IF THE STRETCH IS MAINTAINED (CONTINUED), THE MUSCLE RELAXES. 26-Jan-16 22Dr. Ashok Solanki
  • 23. UMN lesions •weakness, paralysis •spasticity • tendon reflexes •+ Babinski sign •little,if any,muscle atrophy •no fasiculation LMN lesions •weakness, paralysis •flaccidity, hypotonia •Hypo- /no tendon reflex • - Babinski sign •muscle atrophy •fasiculation of involved muscle 26-Jan-16 23Dr. Ashok Solanki
  • 24. VISCERAL REFLEXES  PUPILLARY REFLEXES: DIRECT LIGHT REFLEX INDIRECT OR CONSENSUAL LIGHT REFLEX  ACCOMODATION REFLEX: CONSTRICTION OF PUPIL, CONVERGENCE OF EYE BALLS, INCREASE IN ANTERIOR CURVATURE OF LENS  CILIOSPINAL REFLEX: STIMULATION OF SKIN IN NECK –DILATATION OF PUPILS  OCULOCARDIAC REFLEX: PRESSURE OVER EYEBALLS - BRADYCARDIA 26-Jan-16 24Dr. Ashok Solanki
  • 25. PATHOLOGICAL REFLEXES  BABINSKI’S SIGN + Dorsiflexion of great toe and fanning of other toes.  CLONUS  PENDULAR MOVEMENTS 26-Jan-16 25Dr. Ashok Solanki
  • 29. Flexor reflex (Withdrawal, "hot stove")1. receptors sense pain 2. sensory impulse to spinal cord 3. synapse to association neuron, synapse to motor neurons  polysynaptic 4. motor neurons to flexor muscles to 5. withdraw offended body part from stimulus 26-Jan-16 Dr. Ashok Solanki 29
  • 31. Spinal reflexes Static stretch reflex- maintain the tone Maintain constant degree of muscle contraction (Tone) Continuous static receptor signal → transmitted via both primary and secondary neurons → S.C → continuous command by static gamma motor neurons → Tone. Normal tone is due to continuous dischrge 26-Jan-16 31Dr. Ashok Solanki
  • 32. Stretch reflex 2 types -Response that is transmitted: Dynemic: -when there is change in the length of the spindle receptor (stretching of the sensory receptor area of the muscle spindle by stretching of the muscle spindle or the whole muscle). Detect Change in length. -transmitted by the primary fiber Aα type Static continuous information about the length of the muscle (not the change in length). transmitted by both the primary Aα and secondary (Aβ and Aγ) 26-Jan-16 32Dr. Ashok Solanki
  • 33. APPLIED: Decreased (hypoactive) stretch reflex: Destruction of sensory or motor nerve to the muscle Stimulation of inhibitory areas in brain Inhibition of facilitatory areas in the brain Hypothyroidism 26-Jan-16 33Dr. Ashok Solanki
  • 34. Importance or use of stretch reflex:  1. Tone maintenance  2. Maintenance of posture  3. Control of voluntary movements 26-Jan-16 34Dr. Ashok Solanki
  • 35. What are the components of reflex action?  Components of reflex forms reflex arc involving 1. receptor- sensory organ 2. afferent neuron- 3. centre 4. efferent neuron 5. effector organ 3526-Jan-16 Dr. Ashok Solanki
  • 36. Reflex arc  Diagram showing complete reflex arc 3626-Jan-16 Dr. Ashok Solanki
  • 37. Dr. Ashok Solanki 3726-Jan-16
  • 38. Dr. Ashok Solanki 3826-Jan-16
  • 39. 2. 5 Essential Components of the Reflex Arc 39 Dr. Ashok Solanki Stimulus at distal end of neuron Skin Spinal cord (in cross section) Interneuron Receptor Effector Sensory neuron Motor neuron Integration center (a) 26-Jan-16 Dr. Ashok Solanki