SlideShare ist ein Scribd-Unternehmen logo
1 von 34
Proximal Femur Fractures
Jeffrey Shyu, MD
Learning Objectives
Provide an intuitive understanding of the
morphologic types, injury mechanisms, and
classification systems of adult proximal femur
fractures, using multimodality imaging
examples, 3-D models, and animations.
Review the potential complications and
management.
Disclosures
Learning
Objectives
Organization
Anatomy
Imaging
Osteochondral
Subchondral
Femoral Neck
Intertrochanteric
Greater Troch.
Lesser Troch.
Subtrochanteric
Conclusion
References
Proximal Femur Fractures:
Organization Tree
* Basicervical fractures, although intracapsular, are managed like intertrochanteric fractures.
Proximal Femur Fractures
Femoral Head
Osteochondral
Subchondral
Extracapsular
Intertrochanteric
Greater Trochanter
Lesser Trochanter
Subtrochanteric
Intracapsular
Basicervical*
Transcervical
Subcapital
Proximal femur fractures may be divided into femoral head, intracapsular femoral neck, and
extracapsular fractures. Accurately categorizing the anatomic location and subtype of the
fracture has significant implications for surgical management.
Disclosures
Learning
Objectives
Organization
Anatomy
Imaging
Osteochondral
Subchondral
Femoral Neck
Intertrochanteric
Greater Troch.
Lesser Troch.
Subtrochanteric
Conclusion
References
osteochondral fracturesubchondral fracturesubcapital fracturetranscervical fracturebasicervical fractureintertrochanteric fracturegreater trochanter fracturelesser trochanter fracturesubtrochanteric fracture
Proximal Femur Fractures
Disclosures
Learning
Objectives
Organization
Anatomy
Imaging
Osteochondral
Subchondral
Femoral Neck
Intertrochanteric
Greater Troch.
Lesser Troch.
Subtrochanteric
Conclusion
References
Anatomy
MOVIE: Computer generated tour of the relevant muscular, ligamentous, labral, and bony
anatomy of the hip.
Disclosures
Learning
Objectives
Organization
Anatomy
Imaging
Osteochondral
Subchondral
Femoral Neck
Intertrochanteric
Greater Troch.
Lesser Troch.
Subtrochanteric
Conclusion
References
Anatomy
The hip is a synovial joint with wide range of rotational motion and stability
Stability is conferred by its ball and deep socket configuration, acetabular labrum, a strong joint capsule,
articular cartilage, and surrounding muscle
One of the few inherently stable joints because of its bony anatomy
Iliofemoral and pubofemoral ligaments cover hip joint anteriorly. Ischiofemoral ligament covers hip joint
posteriorly
Byrne DP et al. The Open Sports Medicine Journal 2010
Disclosures
Learning
Objectives
Organization
Anatomy
Imaging
Osteochondral
Subchondral
Femoral Neck
Intertrochanteric
Greater Troch.
Lesser Troch.
Subtrochanteric
Conclusion
References
Anatomy: Arterial Supply
Medial femoral circumflex artery
• Largest, most important contributor
• Posterior portion of vascular ring
• Supplies superolateral femoral head
Lateral femoral circumflex artery
• Anterior portion of vascular ring
• Supplies inferoanterior femoral head
Obdurator artery
• Via ligamentum teres
• Little supply to femoral head, inadequate in
setting of displaced head/heck fractures
Ascending cervical arteries
• Feeder vessels arising from extracapsular ring
• Penetrate capsule
• Run parallel to femoral neck towards the head
• Lateral vessels provide greatest supply
A major concern of femoral head and
neck fractures is disruption of the
arterial supply, which results in
avascular necrosis. In fractures, the
intraosseous cervical vessels are
disrupted.
Trueta J et al. J Bone Joint Surg BR 1953; Ly TV et al. J Boint Joint Surg Am 2008.
Disclosures
Learning
Objectives
Organization
Anatomy
Imaging
Osteochondral
Subchondral
Femoral Neck
Intertrochanteric
Greater Troch.
Lesser Troch.
Subtrochanteric
Conclusion
References
Lat. fem
circumflex
Med. fem
circumflex
Deep femoral
art.
Obdurator art.
Hip experiences combined
mechanical loads
• Axial load along shaft, compressive stress
• Bending load along neck, tensile stress applied
at upper neck and compressive stress at lower
neck
Cancellous bone arranged along
principal lines of stress
• Primary medial trabeculae resist compression
• Primary lateral trabeculae resist tension
Stress lines explain patterns of injury
Ward’s Triangle: Weakest point of
femoral neck
Tensile groupCompressive group
Ward’s Triangle
Anatomy: Stress Lines
Byrne DP et al. The Open Sports Medicine Journal 2010; Bowman KF Arthroscopy 2010.
Disclosures
Learning
Objectives
Organization
Anatomy
Imaging
Osteochondral
Subchondral
Femoral Neck
Intertrochanteric
Greater Troch.
Lesser Troch.
Subtrochanteric
Conclusion
References
Imaging Modalities
Dominguez S et al. Acad Emerg Med 2005; Frihagen F et al. Acta Orthop 2005; Kirby MW et al. AJR Am J Roentgenol 2010; Khurana B et al. AJR 2012
Plain Film Radiography
• First line study
• 90% sensitive, however 2-11% of ED patients
have radiologically occult fractures
• AP and lateral radiographs of the hip
• AP radiograph of the pelvis, to assess for
pelvic injury and compare with contralateral
hip
CT
• More readily accessible than MRI in acute ED
settings
• Useful in trauma for detecting intra-articular
extension, acetabular fracture, pelvic ring, and
sacral fractures
• However, second-line compared to MRI
because of concerns for missing fracture lines
• May be useful for preoperative evaluation
Disclosures
Learning
Objectives
Organization
Anatomy
Imaging
Osteochondral
Subchondral
Femoral Neck
Intertrochanteric
Greater Troch.
Lesser Troch.
Subtrochanteric
Conclusion
References
Coronal CT demonstrates a valgus impacted
femoral neck fracture
Imaging Modalities
Dominguez S et al. Acad Emerg Med 2005; Frihagen F et al. Acta Orthop 2005; Kirby MW et al. AJR Am J Roentgenol 2010 Khurana B et al. AJR 2012
MRI
• Obtain if radiographs are negative/equivocal and clinical suspicion is high
• More sensitive than CT for evaluating occult fractures
• Best for evaluating bone marrow, joint space, osteochondral injuries, early diagnosis
and staging of AVN
• May be limited in access in an acute ED setting
• Technique: Useful MR sequences include the following: coronal STIR, coronal T1, axial
dual-echo, axial T2 fat-saturated FSE, axial fat-saturated FSE proton density, sagittal
T1, axial T1.
• Most useful sequences are coronal STIR (for edema) and coronal T1 (for fracture line)
Bone Scan
• Indicated for suspected fracture or AVN not demonstrated on plain film, and where MRI
unavailable
• High sensitivity, but poor specificity
• Minimum of 4 hours to perform, and may take up to 24-48 hours
• Relatively less useful in osteoporotic patients
• Poor spatial localization of fracture lines
Disclosures
Learning
Objectives
Organization
Anatomy
Imaging
Osteochondral
Subchondral
Femoral Neck
Intertrochanteric
Greater Troch.
Lesser Troch.
Subtrochanteric
Conclusion
References
Occult Femoral Neck Fracture
Seen Only on MRI
Dominguez S et al. Acad Emerg Med 2005
AP radiograph of the hip demonstrates no
evidence of fracture.
On coronal T1 MRI, a hypointense fracture
line is present.
Up to 11% of ED patients have radiologically occult hip fractures
Disclosures
Learning
Objectives
Organization
Anatomy
Imaging
Osteochondral
Subchondral
Femoral Neck
Intertrochanteric
Greater Troch.
Lesser Troch.
Subtrochanteric
Conclusion
References
Traumatic Femoral Head
(Osteochondral) Fractures
Traumatic femoral head fractures typically result from high energy impact, and are often
associated with hip dislocations
Posterior dislocations 9x more common than anterior
Partial flexion, internal rotation typically leads to a posterior fracture-dislocation pattern
Ross JR et al. Curr Rev Musculosk Med. 2012
Disclosures
Learning
Objectives
Organization
Anatomy
Imaging
Osteochondral
Subchondral
Femoral Neck
Intertrochanteric
Greater Troch.
Lesser Troch.
Subtrochanteric
Conclusion
References
Femoral Head Fractures:
Pipkin Classification
Posterior dislocation
Fracture below fovea, non-weight-bearing
Posterior dislocation
Fracture above fovea, weight-bearing
Associated femoral neck fracture Type I, II, or III, associated acetabular fracture
Rockwood and Green’s Fractures in Adults 2010; Ross JR et al. Curr Rev Musculosk Med 2012
Most commonly used classification for femoral head fractures, and used to guide
operative versus nonoperative managementDisclosures
Learning
Objectives
Organization
Anatomy
Imaging
Osteochondral
Subchondral
Femoral Neck
Intertrochanteric
Greater Troch.
Lesser Troch.
Subtrochanteric
Conclusion
References
Traumatic Femoral
Head Fractures
Disclosures
Learning
Objectives
Organization
Anatomy
Imaging
Osteochondral
Subchondral
Femoral Neck
Intertrochanteric
Greater Troch.
Lesser Troch.
Subtrochanteric
Conclusion
References
Femoral head fracture with posterior dislocationFemoral head fracture with subfoveal
involvement (Pipkin I)
Traumatic Femoral Head Fractures:
Surgical Considerations
Intra-capsular fracture, concern for avascular necrosis
• Emergent closed reduction as soon as feasible, preferably within 6 hours
• If irreducible, or with femoral neck fracture, then ORIF
Above or below fovea?
• Above fovea, weight bearing
• Below fovea, non-weight bearing, could potentially be treated conservatively
Is traction indicated?
• If fracture flipped, then traction indicated
Congruent?
• If incongruent, then operative management
Management Strategies
• Conservative management: Pipkin I
• ORIF: Pipkin II, Pipkin III, IV, irreducible fracture-dislocation
• Core decompression for osteonecrosis is controversial
Rockwood and Green’s Fractures in Adults 2010; Ross JR et al. Curr Rev Musculosk Med. 2012
Disclosures
Learning
Objectives
Organization
Anatomy
Imaging
Osteochondral
Subchondral
Femoral Neck
Intertrochanteric
Greater Troch.
Lesser Troch.
Subtrochanteric
Conclusion
References
Subchondral Insufficiency
Versus Osteonecrosis
Osteonecrosis
• Typically 30s-40s in age
• Associated with steroid/alcohol use
• 50-70 percent bilateral
MRI
• T1: Smooth band that is concave to the articular surface,
and circumscribes necrotic segments
Treatment
• No femoral head collapse: conservative treatment
• Femoral head collapse: THA or hemiarthroplasty
Yamamoto T Clin Orthop Surg 2012; Ikemura S et al. AJR 2010
Subchondral insufficiency fractures are a recently recognized entity that may mimic osteonecrosis of the
femoral head. However, certain clinical and imaging features will favor one diagnosis over the other.
Osteonecrosis: coronal T1: bilateral decreased T1 signal in the femoral
heads, and serpiginous bands concave to articular surface
Disclosures
Learning
Objectives
Organization
Anatomy
Imaging
Osteochondral
Subchondral
Femoral Neck
Intertrochanteric
Greater Troch.
Lesser Troch.
Subtrochanteric
Conclusion
References
A B
Subchondral Insufficiency
• Biphasic pattern: elderly females and young active individuals
• Typically unilateral
MRI
• Irregular, hypointense disconnected band that runs almost
parallel to femoral head
• High signal proximal segment on C+ images
Treatment
• No femoral head collapse
• Young: Trochanteric rotational osteotomy
• Elderly: THA or hemiarthroplasty
Subchondral Insufficiency: coronal STIR (A) demonstrates
irregular band parallel to the femoral head. Post-contrast T1
image (B) in a different patient demonstrates femoral head
enhancement
Femoral Neck Fracture:
Mechanism
Caused by fall with applied force to the greater trochanter
High energy impact in younger patients, and low energy impact in elderly patients
Weakest site just below articular surface
Disclosures
Learning
Objectives
Organization
Anatomy
Imaging
Osteochondral
Subchondral
Femoral Neck
Intertrochanteric
Greater Troch.
Lesser Troch.
Subtrochanteric
Conclusion
References
Subcapital, Transcervical,
Basicervical Fractures
Transcervical
Treated as intracapsular fx
Basicervical
Treated as extracapsular fx
e.g. like intertrochanteric fx
Subcapital
Treated as intracapsular fx
Disclosures
Learning
Objectives
Organization
Anatomy
Imaging
Osteochondral
Subchondral
Femoral Neck
Intertrochanteric
Greater Troch.
Lesser Troch.
Subtrochanteric
Conclusion
References
Incomplete
Valgus impaction + retroversion
Complete, non-displaced
Marked angulation
Minimal/no proximal translation
Complete displacement
Proximal translation
Commonly used classification for
surgical management of femoral
neck fractures
Valgus impacted fractures are
often missed
Good interobserver agreement
between I-II and III-IV, but poor
between all groups
Better to distinguish I-II and III-IV,
as types III and IV typically treated
with arthroplasty
IVIII
I II
Garden Classification
Frandsen PA et al. Acta Orthop Scand 1984; Kreder HJ J Bone Joint Surg AM 2002
Disclosures
Learning
Objectives
Organization
Anatomy
Imaging
Osteochondral
Subchondral
Femoral Neck
Intertrochanteric
Greater Troch.
Lesser Troch.
Subtrochanteric
Conclusion
References
Pauwel Classification
Type I
More stable
Type III
More unstable, higher energy injury
Determined by angle of fracture from horizontal plane
Increased shear forces with increased angles worsens prognosis
Better categorizes stability than the Garden Classification
Better predicts difficulty of obtaining stable fixation
More vertically oriented fractures may also require plate fixation
Type III fractures complicated by nonunion may require intertrochanteric osteotomy to reorient the fracture
line to a more Type 1 (stable) angle
Ly TV et al. J Bone Joint Surg Am 2008
Disclosures
Learning
Objectives
Organization
Anatomy
Imaging
Osteochondral
Subchondral
Femoral Neck
Intertrochanteric
Greater Troch.
Lesser Troch.
Subtrochanteric
Conclusion
References
Type II
Most common
Types of Stress Fractures
Tensile
Unstable, fracture can
propagate
Compressive
More stable
Displaced
Unstable
Worse prognosis and risk for
avascular necrosis
Emergent operation and reduction
Disclosures
Learning
Objectives
Organization
Anatomy
Imaging
Osteochondral
Subchondral
Femoral Neck
Intertrochanteric
Greater Troch.
Lesser Troch.
Subtrochanteric
Conclusion
References
Femoral neck stress fractures are often related to increased activity. The
pattern of the stress fracture relates to the lines of stress within the
proximal femur and has significant management implications
Tensile Stress Fracture
Superior, lateral aspect of the femoral neck
Bimodal distribution: Elderly individuals and young runners
Potentially unstable, obtain MRI to assess fracture extent
Warrants internal fixation (nail fixation in young athletes)
Femoral Neck:
Tensile Stress Fracture
Disclosures
Learning
Objectives
Organization
Anatomy
Imaging
Osteochondral
Subchondral
Femoral Neck
Intertrochanteric
Greater Troch.
Lesser Troch.
Subtrochanteric
Conclusion
References
Femoral Neck:
Tensile Stress Fracture
Tensile stress fracture in the superolateral
femoral neck in an elderly patient. Note
osteoarthritis of the hip.
Tensile stress fracture (Garden III) in the
superolateral femoral neck in a young, active,
patient. Note the normal bone mineral density.
Bimodal distribution: elderly individuals and young runners
Disclosures
Learning
Objectives
Organization
Anatomy
Imaging
Osteochondral
Subchondral
Femoral Neck
Intertrochanteric
Greater Troch.
Lesser Troch.
Subtrochanteric
Conclusion
References
Femoral Neck:
Fatigue Compression Fracture
Fatigue Compression Fracture
Inferior aspect of femoral neck
Active individuals
May potentially be treated non-operatively
Coronal STIR image demonstrates edema at the
inferomedial femoral neck.
Coronal T1 image demonstrates a hypointense
region and a subtle fracture line.
Disclosures
Learning
Objectives
Organization
Anatomy
Imaging
Osteochondral
Subchondral
Femoral Neck
Intertrochanteric
Greater Troch.
Lesser Troch.
Subtrochanteric
Conclusion
References
Femoral Neck Fractures: Surgical
Considerations
AVN, nonunion may result from delayed diagnosis
• Risk for AVN is greater for femoral neck fractures than for pertrochanteric fractures
Young ( < 65) and/or active
• Goal: preserve femoral head, avoid osteonecrosis, achieve union
Old ( > 75) and/or immobile
• Goal: restore mobility and minimize complications
Fracture pattern determines treatment
• Basicervical fracture treated like intertrochanteric fracture
• Nonoperative management associated with higher complication and increased risk of
displacement
• If nondisplaced, internal fixation preferred
• If displaced fracture, elderly, arthroplasty preferred
• Most studies find improved function with THA compared to hemiarthroplasty
Miler BJ et al. J Bone Joint Surg Am 2013; Goh SK et al. J Arthroplasty 2009; Cserhati P et al. Injury 1996
Disclosures
Learning
Objectives
Organization
Anatomy
Imaging
Osteochondral
Subchondral
Femoral Neck
Intertrochanteric
Greater Troch.
Lesser Troch.
Subtrochanteric
Conclusion
References
Femoral Neck Fracture:
Treatment Algorithm
Nondisplaced
Displaced
Total Hip Arthroplasty
Hemiarthroplasty
OldYoung
PC Screw or ArthroplastyPercutaneous Cancellous (PC) Screw
Miler BJ et al. J Bone Joint Surg Am 2013
Open Reduction Internal Fixation
Disclosures
Learning
Objectives
Organization
Anatomy
Imaging
Osteochondral
Subchondral
Femoral Neck
Intertrochanteric
Greater Troch.
Lesser Troch.
Subtrochanteric
Conclusion
References
Intertrochanteric Fracture
Koval KJ et al. J Am Acad Orthop Surg 1994
Nondisplaced Intertrochanteric fracture (Evans I)
Disclosures
Learning
Objectives
Organization
Anatomy
Imaging
Osteochondral
Subchondral
Femoral Neck
Intertrochanteric
Greater Troch.
Lesser Troch.
Subtrochanteric
Conclusion
References
Anatomy
• Intertrochanteric line: anterior ridge between greater and lesser trochanters
• Extracapsular, transition between femoral neck and shaft
• Iliofemoral ligament attaches above, vastus medialis attaches below
Mechanism
• Resulting from fall
Unstable features
• Loss of medial buttress
• 4-part fractures, and 3-part fractures with
lesser trochanter involvement
• Reverse obliquity
• Comminution
Stable features
• Near anatomic reduction achievable
• Lesser trochanter nondisplaced
• Medial cortices in alignment
• No comminution
Evans Classification
Trafton PG. Orthop Clin North Am 1987; Koval KJ et al. J Am Acad Orthop Surg 1994
Disclosures
Learning
Objectives
Organization
Anatomy
Imaging
Osteochondral
Subchondral
Femoral Neck
Intertrochanteric
Greater Troch.
Lesser Troch.
Subtrochanteric
Conclusion
References
I II III
Two part, undisplaced
Stable
Two part, displaced
Stable
Three part, posterolateral comminution
Unstable
Three part, posteromedial comminution
Unstable
Four Part
Unstable
Useful for deciding stability and treatment of intertrochanteric fractures. Also, reverse obliquity
fractures are unstable and treated like subtrochanteric fractures
IV V
Intertrochanteric Fracture:
Management
Incomplete
• Obtain MRI to ensure fracture not complete
• If incomplete and <50% fracture width,
potentially can treat conservatively
• Risk of fracture completion
Complete
• Stable: Dynamic plate and screw
• Unstable or reverse obliquity:
Intramedullary device
Management depends on completeness and stability
Risk of AVN and nonunion less than in femoral neck fractures
Again, basicervical fractures treated like intertrochanteric fractures
Su BW, Orthopedics 2006; Forte ML et al. J Bone Jint Surg Am 2008
Disclosures
Learning
Objectives
Organization
Anatomy
Imaging
Osteochondral
Subchondral
Femoral Neck
Intertrochanteric
Greater Troch.
Lesser Troch.
Subtrochanteric
Conclusion
References
Greater Trochanter Fracture
Anatomy
• Greater trochanter is the insertion site for hip
abductors (gluteus medius and minimus) and
external rotators (piriformis, gemelli, obdurators)
Mechanism
• Isolated greater trochanter fracture may be related
to impaction from fall, versus avulsion
Imaging
• If incomplete, obtain MRI to assess extent of
fracture
Management
• Most heal well with nonoperative management
• If significant displacement, then ORIF
Disclosures
Learning
Objectives
Organization
Anatomy
Imaging
Osteochondral
Subchondral
Femoral Neck
Intertrochanteric
Greater Troch.
Lesser Troch.
Subtrochanteric
Conclusion
References
Lesser Trochanter Fracture
Anatomy
• Lesser trochanter is attachment site for iliopsoas
Mechanism
• Fracture may be due to avulsion
• In the absence of injury, isolated lesser
trochanter fracture is highly suspicious for an
underlying malignancy
Imaging
• Obtain MRI to assess extent of fracture
• Evaluate for underlying malignancy
Management
• Nondisplaced fractures heal well with
nonoperative management
• If significantly displaced, then ORIF
James SL et al. Eur Radiol 2006
Mildly displaced lateral trochanter fracture
in a patient with prostate cancer and
diffuse blastic metastases. Also note the
extensive periosteal reaction.
Disclosures
Learning
Objectives
Organization
Anatomy
Imaging
Osteochondral
Subchondral
Femoral Neck
Intertrochanteric
Greater Troch.
Lesser Troch.
Subtrochanteric
Conclusion
References
Subtrochanteric and Proximal Femoral Shaft:
Traumatic Versus Atypical Fractures
Shane E et al. J Bone Miner Res 2010. Park-Wyllie LY et al. JAMA 2011
Atypical Fractures
Long-term bisphosphonate usage, o/minimal trauma
Imaging
Typically subtrochanteric or femoral shaft
Transverse or short oblique orientation
Lateral beaking (arrow)
Normal bone mineral density
Management
Evaluate contralateral femur
Treat with ORIF, intramedullary nail and screw0
It is important for the radiologist to recognize the different patterns of traumatic and
atypical subtrochanteric and proximal shaft fractures
Disclosures
Learning
Objectives
Organization
Anatomy
Imaging
Osteochondral
Subchondral
Femoral Neck
Intertrochanteric
Greater Troch.
Lesser Troch.
Subtrochanteric
Conclusion
References Typical Fractures
Often traumatic, high impact
Imaging
Radiographs generally diagnostic
Oblique or spiral in orientation
Proximal piece is flexed, abducted, and externally rotated
MR/CT if concern for pathologic fracture
Management
ORIF
Higher rates of failure due to high stress anatomy
Conclusion
• Proximal femoral fractures can be classified as
femoral head, intracapsular, and extracapsular
• Increased concern for AVN and nonunion for
intracapsular fractures due to vascular compromise
• Important to understand how imaging features reflect
underlying mechanical forces and mechanisms of
injury, and how these in turn guide management
• If a patient has hip pain and negative x-rays, strongly
consider further imaging with MRI
Disclosures
Learning
Objectives
Organization
Anatomy
Imaging
Osteochondral
Subchondral
Femoral Neck
Intertrochanteric
Greater Troch.
Lesser Troch.
Subtrochanteric
Conclusion
References
References
• Trueta J, Harrison MH. The normal vascular anatomy of the femoral head in adult man. J Bone Joint Surg Br. 1953;35:442-61
• Ly TV, Swiontkowski MF. Treatment of femoral neck fractures in young adults. J Bone Joint Surg Am. 2008;90:2. 254-66
• Byrne DP et al. The Open Sports Medicine Journal 2010;4;51-7.
• Bowman KF Jr, Fox J, Sekiya JK. A clinically relevant review of hip biomechanics. Arthroscopy 2010;26(8):1118-29.
• Dominguez S, Liu P, Roberts C et al. Prevalence of traumatic hip and pelvic fractures in patients with suspected hip fracture and negative initial
standard radiographs—a study of emergency department patients. Acad Emerg Med 2005;12(4):366-9.
• Frihagen F, Nordsletten L, Tariq R, et al. MRI diagnosis of occult hip fractures. Acta Orthop 2005;76(4):524-30.
• Kirby MW, Spritzer C. Radiographic detection of hip and pelvic fractures in the emergency department. AJR Am J Roentgenol 2010;194(4):1054-60.
• Khurana B, Okanobo H, Ossiani M, et al. Abbreviated MRI for patients presenting to the emergency department with hip pain. AJR Am J Roentgenol
2012;198(6):581-8.
• Ross JR, Gardner MJ. Femoral head fractures. Curr Rev Musculoskelet Med 2012;5(3):199-205.
• Rockwood and Green’s Fractures in Adults, 7th Edition. Wolters Kluwer/Lippincott Williams & Wiilkins, New York, 2010.
• Yamamoto T. Subchondral insufficiency fractures of the femoral head. Clin Orthop Surg. 2012:4(3):173-80.
• Ikemura S, Yamamoto T, Motomura G, et al. MRI evaluation of collapsed femoral heads in patients 60 years old or older: differentiation of subchondral
insufficiency fracture from osteonecrosis of the femoral head. AJR Am J Roentgenol 2010;195:W63-W68.
• Frandsen PA, Andersen PE Jr, Christoffersen H et al. Osteosynthesis of femoral neck fracture. The sliding-screw-plate with or without compression.
Acta Orthop Scand 1984;55(6):620-3.
• Kreder HJ. Arthroscopy led to fewer failures and more complications than did internal fixation for displaced fractures of the femoral neck. J Bone Joint
Surg Am 2002;84:2108.
• Miller BJ, Lu X, Cram P. The Trends in Treatment of Femoral Neck Fractures in the Medicare Population from 1991 to 2008. J Bone Joint Surg Am
2013:95(18):1-8.
• Goh SK, Samuel M, Su DHC et al. Meta-analysis comparing total hip arthroplasty with hemiarthroplasty in the treatment of displaced neck of femur
fracture. J Arthroplasty. 2009:24(13):400-6.
• Koval KJ, Zuckerman JD. Hip fractures, II: evaluation and treatment of intertrochanteric fractures. J Am Acad Orthop Surg 1994;2(3):150-6.
• Trafton PG. Subtrochanteric-intertrochanteric femoral fractures. Orthop Clin North Am 1987;18(1):59-71.
• Su BW, Heyworth BE, Protopsaltis TS et al. Basicervical versus intertrochanteric fractures: an analysis of radiographic and functional outcomes.
Orthopedics 2006;29(10):919-25.
• Forte ML, Vimig BA, Kane RL. Geographic variation in device use for intertrochanteriic hif fractures. J Bone Joint Surg Am 2008;90(4):691-9.
• James Sl, Davies Am. Atraumatic avulsion of the lesser trochanter as an indicator of tumour infiltration. Eur Radiol. 2006;16(2):512-4
• Shane E, Burr D, Ebeling PR et al. Atypical subtrochanteric and diaphyseal femoral fractures: report of a task force of the American Society of Bone
and Mineral Research 2010; 25(11):2267-94
• Park-Wyllie LY, Mamdani MM, Juurlink DN. Bisphosphonate use and the risk of subtrochanteric or femoral shaft fractures in older women. JAMA
2011;305(8):783-9.
• Tornetta P III. Subtrochanteric femur fracture. J Orthop Trauma 2002;16(4);280-3
Thank You For Viewing Our Exhibit – Jeffrey Shyu (jshyu@partners.org)
Disclosures
Learning
Objectives
Organization
Anatomy
Imaging
Osteochondral
Subchondral
Femoral Neck
Intertrochanteric
Greater Troch.
Lesser Troch.
Subtrochanteric
Conclusion
References

Weitere ähnliche Inhalte

Was ist angesagt?

Presentation1.pptx, radiological imaging of anteversion angle.
Presentation1.pptx, radiological imaging of anteversion angle.Presentation1.pptx, radiological imaging of anteversion angle.
Presentation1.pptx, radiological imaging of anteversion angle.
Abdellah Nazeer
 
Presentation1.pptx, interpretation of x ray on bone tumour.
Presentation1.pptx, interpretation of x ray on bone tumour.Presentation1.pptx, interpretation of x ray on bone tumour.
Presentation1.pptx, interpretation of x ray on bone tumour.
Abdellah Nazeer
 
Calcaneus fractures by dr sidhu
Calcaneus fractures by dr sidhuCalcaneus fractures by dr sidhu
Calcaneus fractures by dr sidhu
Harsimran Sidhu
 
Fractures Of The Distal Radius
Fractures Of The Distal RadiusFractures Of The Distal Radius
Fractures Of The Distal Radius
navigator13
 

Was ist angesagt? (20)

Unipolar vs bipolar
Unipolar vs bipolarUnipolar vs bipolar
Unipolar vs bipolar
 
Fracture of Distal End Humerus.
Fracture of Distal End Humerus.Fracture of Distal End Humerus.
Fracture of Distal End Humerus.
 
Inter trochanteric femoral fractures
Inter trochanteric femoral fracturesInter trochanteric femoral fractures
Inter trochanteric femoral fractures
 
Presentation1.pptx, radiological imaging of anteversion angle.
Presentation1.pptx, radiological imaging of anteversion angle.Presentation1.pptx, radiological imaging of anteversion angle.
Presentation1.pptx, radiological imaging of anteversion angle.
 
Patellar Instability
Patellar InstabilityPatellar Instability
Patellar Instability
 
Spinal fractures classification - Core Surgical Trainees' teaching
Spinal fractures classification - Core Surgical Trainees' teachingSpinal fractures classification - Core Surgical Trainees' teaching
Spinal fractures classification - Core Surgical Trainees' teaching
 
Femoral notching in total knee arthroplasty
Femoral notching in total knee arthroplastyFemoral notching in total knee arthroplasty
Femoral notching in total knee arthroplasty
 
CORA (center of rotation of angulation)
CORA (center of rotation of angulation)CORA (center of rotation of angulation)
CORA (center of rotation of angulation)
 
Aseptic loosening total hip arthroplasty
Aseptic loosening total hip arthroplastyAseptic loosening total hip arthroplasty
Aseptic loosening total hip arthroplasty
 
Proximal femur fractures
Proximal femur fracturesProximal femur fractures
Proximal femur fractures
 
Intertrochanteric & subtrochanteric fracture classification
Intertrochanteric & subtrochanteric fracture classificationIntertrochanteric & subtrochanteric fracture classification
Intertrochanteric & subtrochanteric fracture classification
 
Intertrochanteric fractures and its management with DHS or PFN or Arthroplast...
Intertrochanteric fractures and its management with DHS or PFN or Arthroplast...Intertrochanteric fractures and its management with DHS or PFN or Arthroplast...
Intertrochanteric fractures and its management with DHS or PFN or Arthroplast...
 
Thoraco Lumbar Spine Injury
Thoraco Lumbar Spine InjuryThoraco Lumbar Spine Injury
Thoraco Lumbar Spine Injury
 
Presentation1.pptx, interpretation of x ray on bone tumour.
Presentation1.pptx, interpretation of x ray on bone tumour.Presentation1.pptx, interpretation of x ray on bone tumour.
Presentation1.pptx, interpretation of x ray on bone tumour.
 
Calcaneus fractures by dr sidhu
Calcaneus fractures by dr sidhuCalcaneus fractures by dr sidhu
Calcaneus fractures by dr sidhu
 
Thoracolumbar fractures classification
Thoracolumbar fractures classificationThoracolumbar fractures classification
Thoracolumbar fractures classification
 
Subtrochanteric fracture
Subtrochanteric fractureSubtrochanteric fracture
Subtrochanteric fracture
 
Growth plate & Various disorders affecting growth plate by Dr.Vinay
Growth plate & Various disorders affecting growth plate by Dr.VinayGrowth plate & Various disorders affecting growth plate by Dr.Vinay
Growth plate & Various disorders affecting growth plate by Dr.Vinay
 
Fractures Of The Distal Radius
Fractures Of The Distal RadiusFractures Of The Distal Radius
Fractures Of The Distal Radius
 
26. acetabular fractures anatomy, evaluation and classification - muhammad...
26. acetabular fractures   anatomy, evaluation and classification  - muhammad...26. acetabular fractures   anatomy, evaluation and classification  - muhammad...
26. acetabular fractures anatomy, evaluation and classification - muhammad...
 

Ähnlich wie Proximal Femur Fractures - by Jeffrey Shyu, MD

Spine injury -halim.pptx
Spine injury -halim.pptxSpine injury -halim.pptx
Spine injury -halim.pptx
ezrys54ety5
 
L01_Hip-dislocatinos-femoral-head.ppt
L01_Hip-dislocatinos-femoral-head.pptL01_Hip-dislocatinos-femoral-head.ppt
L01_Hip-dislocatinos-femoral-head.ppt
toto798365
 
Intertrochanteric fractures / hip fracture
Intertrochanteric fractures / hip fractureIntertrochanteric fractures / hip fracture
Intertrochanteric fractures / hip fracture
Mannan Ahmed
 

Ähnlich wie Proximal Femur Fractures - by Jeffrey Shyu, MD (20)

Neck of Femur, IT and Subtrochanteric fracture- Dr Sundar Ortho.pptx
Neck of Femur, IT and Subtrochanteric fracture- Dr Sundar Ortho.pptxNeck of Femur, IT and Subtrochanteric fracture- Dr Sundar Ortho.pptx
Neck of Femur, IT and Subtrochanteric fracture- Dr Sundar Ortho.pptx
 
Fracture of neck of femur
Fracture of neck of femurFracture of neck of femur
Fracture of neck of femur
 
Spine injury -halim.pptx
Spine injury -halim.pptxSpine injury -halim.pptx
Spine injury -halim.pptx
 
fracture of neck of femur
fracture of neck of femurfracture of neck of femur
fracture of neck of femur
 
Non union neck of femur
Non union neck of femurNon union neck of femur
Non union neck of femur
 
Capitellum fractures
Capitellum fracturesCapitellum fractures
Capitellum fractures
 
Orthopedics 5th year, 5th lecture (Dr. Ali A.Nabi)
Orthopedics 5th year, 5th lecture (Dr. Ali A.Nabi)Orthopedics 5th year, 5th lecture (Dr. Ali A.Nabi)
Orthopedics 5th year, 5th lecture (Dr. Ali A.Nabi)
 
Traumatic spinal injury
Traumatic spinal injuryTraumatic spinal injury
Traumatic spinal injury
 
Terrible triad of the elbow
Terrible triad of the elbowTerrible triad of the elbow
Terrible triad of the elbow
 
Humerus fracture
Humerus fractureHumerus fracture
Humerus fracture
 
Nof fracture
Nof fractureNof fracture
Nof fracture
 
Clavicle fractures
Clavicle fractures Clavicle fractures
Clavicle fractures
 
Intracapsular femoral neck fractures anatomy and biomechanics
Intracapsular femoral neck fractures anatomy and biomechanicsIntracapsular femoral neck fractures anatomy and biomechanics
Intracapsular femoral neck fractures anatomy and biomechanics
 
Proximal humerus fractures
Proximal humerus fracturesProximal humerus fractures
Proximal humerus fractures
 
L01_Hip-dislocatinos-femoral-head.ppt
L01_Hip-dislocatinos-femoral-head.pptL01_Hip-dislocatinos-femoral-head.ppt
L01_Hip-dislocatinos-femoral-head.ppt
 
Intertrochanteric fracture femur
Intertrochanteric fracture femurIntertrochanteric fracture femur
Intertrochanteric fracture femur
 
Condyle Fractures.pptx
Condyle Fractures.pptxCondyle Fractures.pptx
Condyle Fractures.pptx
 
Cervical Hybrid Arthroplasty by Pablo Pazmino MD
Cervical Hybrid Arthroplasty by Pablo Pazmino MDCervical Hybrid Arthroplasty by Pablo Pazmino MD
Cervical Hybrid Arthroplasty by Pablo Pazmino MD
 
Intertrochentric femur fracture by DR.NAVEEN RATHOR
Intertrochentric femur fracture by DR.NAVEEN RATHORIntertrochentric femur fracture by DR.NAVEEN RATHOR
Intertrochentric femur fracture by DR.NAVEEN RATHOR
 
Intertrochanteric fractures / hip fracture
Intertrochanteric fractures / hip fractureIntertrochanteric fractures / hip fracture
Intertrochanteric fractures / hip fracture
 

KĂźrzlich hochgeladen

Call Girl In Pune 👉 Just CALL ME: 9352988975 💋 Call Out Call Both With High p...
Call Girl In Pune 👉 Just CALL ME: 9352988975 💋 Call Out Call Both With High p...Call Girl In Pune 👉 Just CALL ME: 9352988975 💋 Call Out Call Both With High p...
Call Girl In Pune 👉 Just CALL ME: 9352988975 💋 Call Out Call Both With High p...
chetankumar9855
 
Russian Call Girls Lucknow Just Call 👉👉7877925207 Top Class Call Girl Service...
Russian Call Girls Lucknow Just Call 👉👉7877925207 Top Class Call Girl Service...Russian Call Girls Lucknow Just Call 👉👉7877925207 Top Class Call Girl Service...
Russian Call Girls Lucknow Just Call 👉👉7877925207 Top Class Call Girl Service...
adilkhan87451
 
🌹Attapur⬅️ Vip Call Girls Hyderabad 📱9352852248 Book Well Trand Call Girls In...
🌹Attapur⬅️ Vip Call Girls Hyderabad 📱9352852248 Book Well Trand Call Girls In...🌹Attapur⬅️ Vip Call Girls Hyderabad 📱9352852248 Book Well Trand Call Girls In...
🌹Attapur⬅️ Vip Call Girls Hyderabad 📱9352852248 Book Well Trand Call Girls In...
Call Girls In Delhi Whatsup 9873940964 Enjoy Unlimited Pleasure
 

KĂźrzlich hochgeladen (20)

Andheri East ) Call Girls in Mumbai Phone No 9004268417 Elite Escort Service ...
Andheri East ) Call Girls in Mumbai Phone No 9004268417 Elite Escort Service ...Andheri East ) Call Girls in Mumbai Phone No 9004268417 Elite Escort Service ...
Andheri East ) Call Girls in Mumbai Phone No 9004268417 Elite Escort Service ...
 
The Most Attractive Hyderabad Call Girls Kothapet 𖠋 9332606886 𖠋 Will You Mis...
The Most Attractive Hyderabad Call Girls Kothapet 𖠋 9332606886 𖠋 Will You Mis...The Most Attractive Hyderabad Call Girls Kothapet 𖠋 9332606886 𖠋 Will You Mis...
The Most Attractive Hyderabad Call Girls Kothapet 𖠋 9332606886 𖠋 Will You Mis...
 
Coimbatore Call Girls in Thudiyalur : 7427069034 High Profile Model Escorts |...
Coimbatore Call Girls in Thudiyalur : 7427069034 High Profile Model Escorts |...Coimbatore Call Girls in Thudiyalur : 7427069034 High Profile Model Escorts |...
Coimbatore Call Girls in Thudiyalur : 7427069034 High Profile Model Escorts |...
 
Night 7k to 12k Chennai City Center Call Girls 👉👉 7427069034⭐⭐ 100% Genuine E...
Night 7k to 12k Chennai City Center Call Girls 👉👉 7427069034⭐⭐ 100% Genuine E...Night 7k to 12k Chennai City Center Call Girls 👉👉 7427069034⭐⭐ 100% Genuine E...
Night 7k to 12k Chennai City Center Call Girls 👉👉 7427069034⭐⭐ 100% Genuine E...
 
Independent Call Girls In Jaipur { 8445551418 } ✔ ANIKA MEHTA ✔ Get High Prof...
Independent Call Girls In Jaipur { 8445551418 } ✔ ANIKA MEHTA ✔ Get High Prof...Independent Call Girls In Jaipur { 8445551418 } ✔ ANIKA MEHTA ✔ Get High Prof...
Independent Call Girls In Jaipur { 8445551418 } ✔ ANIKA MEHTA ✔ Get High Prof...
 
Manyata Tech Park ( Call Girls ) Bangalore ✔ 6297143586 ✔ Hot Model With Sexy...
Manyata Tech Park ( Call Girls ) Bangalore ✔ 6297143586 ✔ Hot Model With Sexy...Manyata Tech Park ( Call Girls ) Bangalore ✔ 6297143586 ✔ Hot Model With Sexy...
Manyata Tech Park ( Call Girls ) Bangalore ✔ 6297143586 ✔ Hot Model With Sexy...
 
Call Girl In Pune 👉 Just CALL ME: 9352988975 💋 Call Out Call Both With High p...
Call Girl In Pune 👉 Just CALL ME: 9352988975 💋 Call Out Call Both With High p...Call Girl In Pune 👉 Just CALL ME: 9352988975 💋 Call Out Call Both With High p...
Call Girl In Pune 👉 Just CALL ME: 9352988975 💋 Call Out Call Both With High p...
 
Top Rated Hyderabad Call Girls Erragadda ⟟ 9332606886 ⟟ Call Me For Genuine ...
Top Rated  Hyderabad Call Girls Erragadda ⟟ 9332606886 ⟟ Call Me For Genuine ...Top Rated  Hyderabad Call Girls Erragadda ⟟ 9332606886 ⟟ Call Me For Genuine ...
Top Rated Hyderabad Call Girls Erragadda ⟟ 9332606886 ⟟ Call Me For Genuine ...
 
Call Girls Hosur Just Call 9630942363 Top Class Call Girl Service Available
Call Girls Hosur Just Call 9630942363 Top Class Call Girl Service AvailableCall Girls Hosur Just Call 9630942363 Top Class Call Girl Service Available
Call Girls Hosur Just Call 9630942363 Top Class Call Girl Service Available
 
Russian Call Girls Service Jaipur {8445551418} ❤️PALLAVI VIP Jaipur Call Gir...
Russian Call Girls Service  Jaipur {8445551418} ❤️PALLAVI VIP Jaipur Call Gir...Russian Call Girls Service  Jaipur {8445551418} ❤️PALLAVI VIP Jaipur Call Gir...
Russian Call Girls Service Jaipur {8445551418} ❤️PALLAVI VIP Jaipur Call Gir...
 
Premium Bangalore Call Girls Jigani Dail 6378878445 Escort Service For Hot Ma...
Premium Bangalore Call Girls Jigani Dail 6378878445 Escort Service For Hot Ma...Premium Bangalore Call Girls Jigani Dail 6378878445 Escort Service For Hot Ma...
Premium Bangalore Call Girls Jigani Dail 6378878445 Escort Service For Hot Ma...
 
Call Girls Hyderabad Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Hyderabad Just Call 8250077686 Top Class Call Girl Service AvailableCall Girls Hyderabad Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Hyderabad Just Call 8250077686 Top Class Call Girl Service Available
 
Russian Call Girls Lucknow Just Call 👉👉7877925207 Top Class Call Girl Service...
Russian Call Girls Lucknow Just Call 👉👉7877925207 Top Class Call Girl Service...Russian Call Girls Lucknow Just Call 👉👉7877925207 Top Class Call Girl Service...
Russian Call Girls Lucknow Just Call 👉👉7877925207 Top Class Call Girl Service...
 
Premium Call Girls In Jaipur {8445551418} ❤️VVIP SEEMA Call Girl in Jaipur Ra...
Premium Call Girls In Jaipur {8445551418} ❤️VVIP SEEMA Call Girl in Jaipur Ra...Premium Call Girls In Jaipur {8445551418} ❤️VVIP SEEMA Call Girl in Jaipur Ra...
Premium Call Girls In Jaipur {8445551418} ❤️VVIP SEEMA Call Girl in Jaipur Ra...
 
Call Girls Rishikesh Just Call 9667172968 Top Class Call Girl Service Available
Call Girls Rishikesh Just Call 9667172968 Top Class Call Girl Service AvailableCall Girls Rishikesh Just Call 9667172968 Top Class Call Girl Service Available
Call Girls Rishikesh Just Call 9667172968 Top Class Call Girl Service Available
 
Jogeshwari ! Call Girls Service Mumbai - 450+ Call Girl Cash Payment 90042684...
Jogeshwari ! Call Girls Service Mumbai - 450+ Call Girl Cash Payment 90042684...Jogeshwari ! Call Girls Service Mumbai - 450+ Call Girl Cash Payment 90042684...
Jogeshwari ! Call Girls Service Mumbai - 450+ Call Girl Cash Payment 90042684...
 
🌹Attapur⬅️ Vip Call Girls Hyderabad 📱9352852248 Book Well Trand Call Girls In...
🌹Attapur⬅️ Vip Call Girls Hyderabad 📱9352852248 Book Well Trand Call Girls In...🌹Attapur⬅️ Vip Call Girls Hyderabad 📱9352852248 Book Well Trand Call Girls In...
🌹Attapur⬅️ Vip Call Girls Hyderabad 📱9352852248 Book Well Trand Call Girls In...
 
Best Rate (Guwahati ) Call Girls Guwahati ⟟ 8617370543 ⟟ High Class Call Girl...
Best Rate (Guwahati ) Call Girls Guwahati ⟟ 8617370543 ⟟ High Class Call Girl...Best Rate (Guwahati ) Call Girls Guwahati ⟟ 8617370543 ⟟ High Class Call Girl...
Best Rate (Guwahati ) Call Girls Guwahati ⟟ 8617370543 ⟟ High Class Call Girl...
 
Best Rate (Patna ) Call Girls Patna ⟟ 8617370543 ⟟ High Class Call Girl In 5 ...
Best Rate (Patna ) Call Girls Patna ⟟ 8617370543 ⟟ High Class Call Girl In 5 ...Best Rate (Patna ) Call Girls Patna ⟟ 8617370543 ⟟ High Class Call Girl In 5 ...
Best Rate (Patna ) Call Girls Patna ⟟ 8617370543 ⟟ High Class Call Girl In 5 ...
 
Call Girls Rishikesh Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Rishikesh Just Call 8250077686 Top Class Call Girl Service AvailableCall Girls Rishikesh Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Rishikesh Just Call 8250077686 Top Class Call Girl Service Available
 

Proximal Femur Fractures - by Jeffrey Shyu, MD

  • 2. Learning Objectives Provide an intuitive understanding of the morphologic types, injury mechanisms, and classification systems of adult proximal femur fractures, using multimodality imaging examples, 3-D models, and animations. Review the potential complications and management. Disclosures Learning Objectives Organization Anatomy Imaging Osteochondral Subchondral Femoral Neck Intertrochanteric Greater Troch. Lesser Troch. Subtrochanteric Conclusion References
  • 3. Proximal Femur Fractures: Organization Tree * Basicervical fractures, although intracapsular, are managed like intertrochanteric fractures. Proximal Femur Fractures Femoral Head Osteochondral Subchondral Extracapsular Intertrochanteric Greater Trochanter Lesser Trochanter Subtrochanteric Intracapsular Basicervical* Transcervical Subcapital Proximal femur fractures may be divided into femoral head, intracapsular femoral neck, and extracapsular fractures. Accurately categorizing the anatomic location and subtype of the fracture has significant implications for surgical management. Disclosures Learning Objectives Organization Anatomy Imaging Osteochondral Subchondral Femoral Neck Intertrochanteric Greater Troch. Lesser Troch. Subtrochanteric Conclusion References
  • 4. osteochondral fracturesubchondral fracturesubcapital fracturetranscervical fracturebasicervical fractureintertrochanteric fracturegreater trochanter fracturelesser trochanter fracturesubtrochanteric fracture Proximal Femur Fractures Disclosures Learning Objectives Organization Anatomy Imaging Osteochondral Subchondral Femoral Neck Intertrochanteric Greater Troch. Lesser Troch. Subtrochanteric Conclusion References
  • 5. Anatomy MOVIE: Computer generated tour of the relevant muscular, ligamentous, labral, and bony anatomy of the hip. Disclosures Learning Objectives Organization Anatomy Imaging Osteochondral Subchondral Femoral Neck Intertrochanteric Greater Troch. Lesser Troch. Subtrochanteric Conclusion References
  • 6. Anatomy The hip is a synovial joint with wide range of rotational motion and stability Stability is conferred by its ball and deep socket configuration, acetabular labrum, a strong joint capsule, articular cartilage, and surrounding muscle One of the few inherently stable joints because of its bony anatomy Iliofemoral and pubofemoral ligaments cover hip joint anteriorly. Ischiofemoral ligament covers hip joint posteriorly Byrne DP et al. The Open Sports Medicine Journal 2010 Disclosures Learning Objectives Organization Anatomy Imaging Osteochondral Subchondral Femoral Neck Intertrochanteric Greater Troch. Lesser Troch. Subtrochanteric Conclusion References
  • 7. Anatomy: Arterial Supply Medial femoral circumflex artery • Largest, most important contributor • Posterior portion of vascular ring • Supplies superolateral femoral head Lateral femoral circumflex artery • Anterior portion of vascular ring • Supplies inferoanterior femoral head Obdurator artery • Via ligamentum teres • Little supply to femoral head, inadequate in setting of displaced head/heck fractures Ascending cervical arteries • Feeder vessels arising from extracapsular ring • Penetrate capsule • Run parallel to femoral neck towards the head • Lateral vessels provide greatest supply A major concern of femoral head and neck fractures is disruption of the arterial supply, which results in avascular necrosis. In fractures, the intraosseous cervical vessels are disrupted. Trueta J et al. J Bone Joint Surg BR 1953; Ly TV et al. J Boint Joint Surg Am 2008. Disclosures Learning Objectives Organization Anatomy Imaging Osteochondral Subchondral Femoral Neck Intertrochanteric Greater Troch. Lesser Troch. Subtrochanteric Conclusion References Lat. fem circumflex Med. fem circumflex Deep femoral art. Obdurator art.
  • 8. Hip experiences combined mechanical loads • Axial load along shaft, compressive stress • Bending load along neck, tensile stress applied at upper neck and compressive stress at lower neck Cancellous bone arranged along principal lines of stress • Primary medial trabeculae resist compression • Primary lateral trabeculae resist tension Stress lines explain patterns of injury Ward’s Triangle: Weakest point of femoral neck Tensile groupCompressive group Ward’s Triangle Anatomy: Stress Lines Byrne DP et al. The Open Sports Medicine Journal 2010; Bowman KF Arthroscopy 2010. Disclosures Learning Objectives Organization Anatomy Imaging Osteochondral Subchondral Femoral Neck Intertrochanteric Greater Troch. Lesser Troch. Subtrochanteric Conclusion References
  • 9. Imaging Modalities Dominguez S et al. Acad Emerg Med 2005; Frihagen F et al. Acta Orthop 2005; Kirby MW et al. AJR Am J Roentgenol 2010; Khurana B et al. AJR 2012 Plain Film Radiography • First line study • 90% sensitive, however 2-11% of ED patients have radiologically occult fractures • AP and lateral radiographs of the hip • AP radiograph of the pelvis, to assess for pelvic injury and compare with contralateral hip CT • More readily accessible than MRI in acute ED settings • Useful in trauma for detecting intra-articular extension, acetabular fracture, pelvic ring, and sacral fractures • However, second-line compared to MRI because of concerns for missing fracture lines • May be useful for preoperative evaluation Disclosures Learning Objectives Organization Anatomy Imaging Osteochondral Subchondral Femoral Neck Intertrochanteric Greater Troch. Lesser Troch. Subtrochanteric Conclusion References Coronal CT demonstrates a valgus impacted femoral neck fracture
  • 10. Imaging Modalities Dominguez S et al. Acad Emerg Med 2005; Frihagen F et al. Acta Orthop 2005; Kirby MW et al. AJR Am J Roentgenol 2010 Khurana B et al. AJR 2012 MRI • Obtain if radiographs are negative/equivocal and clinical suspicion is high • More sensitive than CT for evaluating occult fractures • Best for evaluating bone marrow, joint space, osteochondral injuries, early diagnosis and staging of AVN • May be limited in access in an acute ED setting • Technique: Useful MR sequences include the following: coronal STIR, coronal T1, axial dual-echo, axial T2 fat-saturated FSE, axial fat-saturated FSE proton density, sagittal T1, axial T1. • Most useful sequences are coronal STIR (for edema) and coronal T1 (for fracture line) Bone Scan • Indicated for suspected fracture or AVN not demonstrated on plain film, and where MRI unavailable • High sensitivity, but poor specificity • Minimum of 4 hours to perform, and may take up to 24-48 hours • Relatively less useful in osteoporotic patients • Poor spatial localization of fracture lines Disclosures Learning Objectives Organization Anatomy Imaging Osteochondral Subchondral Femoral Neck Intertrochanteric Greater Troch. Lesser Troch. Subtrochanteric Conclusion References
  • 11. Occult Femoral Neck Fracture Seen Only on MRI Dominguez S et al. Acad Emerg Med 2005 AP radiograph of the hip demonstrates no evidence of fracture. On coronal T1 MRI, a hypointense fracture line is present. Up to 11% of ED patients have radiologically occult hip fractures Disclosures Learning Objectives Organization Anatomy Imaging Osteochondral Subchondral Femoral Neck Intertrochanteric Greater Troch. Lesser Troch. Subtrochanteric Conclusion References
  • 12. Traumatic Femoral Head (Osteochondral) Fractures Traumatic femoral head fractures typically result from high energy impact, and are often associated with hip dislocations Posterior dislocations 9x more common than anterior Partial flexion, internal rotation typically leads to a posterior fracture-dislocation pattern Ross JR et al. Curr Rev Musculosk Med. 2012 Disclosures Learning Objectives Organization Anatomy Imaging Osteochondral Subchondral Femoral Neck Intertrochanteric Greater Troch. Lesser Troch. Subtrochanteric Conclusion References
  • 13. Femoral Head Fractures: Pipkin Classification Posterior dislocation Fracture below fovea, non-weight-bearing Posterior dislocation Fracture above fovea, weight-bearing Associated femoral neck fracture Type I, II, or III, associated acetabular fracture Rockwood and Green’s Fractures in Adults 2010; Ross JR et al. Curr Rev Musculosk Med 2012 Most commonly used classification for femoral head fractures, and used to guide operative versus nonoperative managementDisclosures Learning Objectives Organization Anatomy Imaging Osteochondral Subchondral Femoral Neck Intertrochanteric Greater Troch. Lesser Troch. Subtrochanteric Conclusion References
  • 14. Traumatic Femoral Head Fractures Disclosures Learning Objectives Organization Anatomy Imaging Osteochondral Subchondral Femoral Neck Intertrochanteric Greater Troch. Lesser Troch. Subtrochanteric Conclusion References Femoral head fracture with posterior dislocationFemoral head fracture with subfoveal involvement (Pipkin I)
  • 15. Traumatic Femoral Head Fractures: Surgical Considerations Intra-capsular fracture, concern for avascular necrosis • Emergent closed reduction as soon as feasible, preferably within 6 hours • If irreducible, or with femoral neck fracture, then ORIF Above or below fovea? • Above fovea, weight bearing • Below fovea, non-weight bearing, could potentially be treated conservatively Is traction indicated? • If fracture flipped, then traction indicated Congruent? • If incongruent, then operative management Management Strategies • Conservative management: Pipkin I • ORIF: Pipkin II, Pipkin III, IV, irreducible fracture-dislocation • Core decompression for osteonecrosis is controversial Rockwood and Green’s Fractures in Adults 2010; Ross JR et al. Curr Rev Musculosk Med. 2012 Disclosures Learning Objectives Organization Anatomy Imaging Osteochondral Subchondral Femoral Neck Intertrochanteric Greater Troch. Lesser Troch. Subtrochanteric Conclusion References
  • 16. Subchondral Insufficiency Versus Osteonecrosis Osteonecrosis • Typically 30s-40s in age • Associated with steroid/alcohol use • 50-70 percent bilateral MRI • T1: Smooth band that is concave to the articular surface, and circumscribes necrotic segments Treatment • No femoral head collapse: conservative treatment • Femoral head collapse: THA or hemiarthroplasty Yamamoto T Clin Orthop Surg 2012; Ikemura S et al. AJR 2010 Subchondral insufficiency fractures are a recently recognized entity that may mimic osteonecrosis of the femoral head. However, certain clinical and imaging features will favor one diagnosis over the other. Osteonecrosis: coronal T1: bilateral decreased T1 signal in the femoral heads, and serpiginous bands concave to articular surface Disclosures Learning Objectives Organization Anatomy Imaging Osteochondral Subchondral Femoral Neck Intertrochanteric Greater Troch. Lesser Troch. Subtrochanteric Conclusion References A B Subchondral Insufficiency • Biphasic pattern: elderly females and young active individuals • Typically unilateral MRI • Irregular, hypointense disconnected band that runs almost parallel to femoral head • High signal proximal segment on C+ images Treatment • No femoral head collapse • Young: Trochanteric rotational osteotomy • Elderly: THA or hemiarthroplasty Subchondral Insufficiency: coronal STIR (A) demonstrates irregular band parallel to the femoral head. Post-contrast T1 image (B) in a different patient demonstrates femoral head enhancement
  • 17. Femoral Neck Fracture: Mechanism Caused by fall with applied force to the greater trochanter High energy impact in younger patients, and low energy impact in elderly patients Weakest site just below articular surface Disclosures Learning Objectives Organization Anatomy Imaging Osteochondral Subchondral Femoral Neck Intertrochanteric Greater Troch. Lesser Troch. Subtrochanteric Conclusion References
  • 18. Subcapital, Transcervical, Basicervical Fractures Transcervical Treated as intracapsular fx Basicervical Treated as extracapsular fx e.g. like intertrochanteric fx Subcapital Treated as intracapsular fx Disclosures Learning Objectives Organization Anatomy Imaging Osteochondral Subchondral Femoral Neck Intertrochanteric Greater Troch. Lesser Troch. Subtrochanteric Conclusion References
  • 19. Incomplete Valgus impaction + retroversion Complete, non-displaced Marked angulation Minimal/no proximal translation Complete displacement Proximal translation Commonly used classification for surgical management of femoral neck fractures Valgus impacted fractures are often missed Good interobserver agreement between I-II and III-IV, but poor between all groups Better to distinguish I-II and III-IV, as types III and IV typically treated with arthroplasty IVIII I II Garden Classification Frandsen PA et al. Acta Orthop Scand 1984; Kreder HJ J Bone Joint Surg AM 2002 Disclosures Learning Objectives Organization Anatomy Imaging Osteochondral Subchondral Femoral Neck Intertrochanteric Greater Troch. Lesser Troch. Subtrochanteric Conclusion References
  • 20. Pauwel Classification Type I More stable Type III More unstable, higher energy injury Determined by angle of fracture from horizontal plane Increased shear forces with increased angles worsens prognosis Better categorizes stability than the Garden Classification Better predicts difficulty of obtaining stable fixation More vertically oriented fractures may also require plate fixation Type III fractures complicated by nonunion may require intertrochanteric osteotomy to reorient the fracture line to a more Type 1 (stable) angle Ly TV et al. J Bone Joint Surg Am 2008 Disclosures Learning Objectives Organization Anatomy Imaging Osteochondral Subchondral Femoral Neck Intertrochanteric Greater Troch. Lesser Troch. Subtrochanteric Conclusion References Type II Most common
  • 21. Types of Stress Fractures Tensile Unstable, fracture can propagate Compressive More stable Displaced Unstable Worse prognosis and risk for avascular necrosis Emergent operation and reduction Disclosures Learning Objectives Organization Anatomy Imaging Osteochondral Subchondral Femoral Neck Intertrochanteric Greater Troch. Lesser Troch. Subtrochanteric Conclusion References Femoral neck stress fractures are often related to increased activity. The pattern of the stress fracture relates to the lines of stress within the proximal femur and has significant management implications
  • 22. Tensile Stress Fracture Superior, lateral aspect of the femoral neck Bimodal distribution: Elderly individuals and young runners Potentially unstable, obtain MRI to assess fracture extent Warrants internal fixation (nail fixation in young athletes) Femoral Neck: Tensile Stress Fracture Disclosures Learning Objectives Organization Anatomy Imaging Osteochondral Subchondral Femoral Neck Intertrochanteric Greater Troch. Lesser Troch. Subtrochanteric Conclusion References
  • 23. Femoral Neck: Tensile Stress Fracture Tensile stress fracture in the superolateral femoral neck in an elderly patient. Note osteoarthritis of the hip. Tensile stress fracture (Garden III) in the superolateral femoral neck in a young, active, patient. Note the normal bone mineral density. Bimodal distribution: elderly individuals and young runners Disclosures Learning Objectives Organization Anatomy Imaging Osteochondral Subchondral Femoral Neck Intertrochanteric Greater Troch. Lesser Troch. Subtrochanteric Conclusion References
  • 24. Femoral Neck: Fatigue Compression Fracture Fatigue Compression Fracture Inferior aspect of femoral neck Active individuals May potentially be treated non-operatively Coronal STIR image demonstrates edema at the inferomedial femoral neck. Coronal T1 image demonstrates a hypointense region and a subtle fracture line. Disclosures Learning Objectives Organization Anatomy Imaging Osteochondral Subchondral Femoral Neck Intertrochanteric Greater Troch. Lesser Troch. Subtrochanteric Conclusion References
  • 25. Femoral Neck Fractures: Surgical Considerations AVN, nonunion may result from delayed diagnosis • Risk for AVN is greater for femoral neck fractures than for pertrochanteric fractures Young ( < 65) and/or active • Goal: preserve femoral head, avoid osteonecrosis, achieve union Old ( > 75) and/or immobile • Goal: restore mobility and minimize complications Fracture pattern determines treatment • Basicervical fracture treated like intertrochanteric fracture • Nonoperative management associated with higher complication and increased risk of displacement • If nondisplaced, internal fixation preferred • If displaced fracture, elderly, arthroplasty preferred • Most studies find improved function with THA compared to hemiarthroplasty Miler BJ et al. J Bone Joint Surg Am 2013; Goh SK et al. J Arthroplasty 2009; Cserhati P et al. Injury 1996 Disclosures Learning Objectives Organization Anatomy Imaging Osteochondral Subchondral Femoral Neck Intertrochanteric Greater Troch. Lesser Troch. Subtrochanteric Conclusion References
  • 26. Femoral Neck Fracture: Treatment Algorithm Nondisplaced Displaced Total Hip Arthroplasty Hemiarthroplasty OldYoung PC Screw or ArthroplastyPercutaneous Cancellous (PC) Screw Miler BJ et al. J Bone Joint Surg Am 2013 Open Reduction Internal Fixation Disclosures Learning Objectives Organization Anatomy Imaging Osteochondral Subchondral Femoral Neck Intertrochanteric Greater Troch. Lesser Troch. Subtrochanteric Conclusion References
  • 27. Intertrochanteric Fracture Koval KJ et al. J Am Acad Orthop Surg 1994 Nondisplaced Intertrochanteric fracture (Evans I) Disclosures Learning Objectives Organization Anatomy Imaging Osteochondral Subchondral Femoral Neck Intertrochanteric Greater Troch. Lesser Troch. Subtrochanteric Conclusion References Anatomy • Intertrochanteric line: anterior ridge between greater and lesser trochanters • Extracapsular, transition between femoral neck and shaft • Iliofemoral ligament attaches above, vastus medialis attaches below Mechanism • Resulting from fall Unstable features • Loss of medial buttress • 4-part fractures, and 3-part fractures with lesser trochanter involvement • Reverse obliquity • Comminution Stable features • Near anatomic reduction achievable • Lesser trochanter nondisplaced • Medial cortices in alignment • No comminution
  • 28. Evans Classification Trafton PG. Orthop Clin North Am 1987; Koval KJ et al. J Am Acad Orthop Surg 1994 Disclosures Learning Objectives Organization Anatomy Imaging Osteochondral Subchondral Femoral Neck Intertrochanteric Greater Troch. Lesser Troch. Subtrochanteric Conclusion References I II III Two part, undisplaced Stable Two part, displaced Stable Three part, posterolateral comminution Unstable Three part, posteromedial comminution Unstable Four Part Unstable Useful for deciding stability and treatment of intertrochanteric fractures. Also, reverse obliquity fractures are unstable and treated like subtrochanteric fractures IV V
  • 29. Intertrochanteric Fracture: Management Incomplete • Obtain MRI to ensure fracture not complete • If incomplete and <50% fracture width, potentially can treat conservatively • Risk of fracture completion Complete • Stable: Dynamic plate and screw • Unstable or reverse obliquity: Intramedullary device Management depends on completeness and stability Risk of AVN and nonunion less than in femoral neck fractures Again, basicervical fractures treated like intertrochanteric fractures Su BW, Orthopedics 2006; Forte ML et al. J Bone Jint Surg Am 2008 Disclosures Learning Objectives Organization Anatomy Imaging Osteochondral Subchondral Femoral Neck Intertrochanteric Greater Troch. Lesser Troch. Subtrochanteric Conclusion References
  • 30. Greater Trochanter Fracture Anatomy • Greater trochanter is the insertion site for hip abductors (gluteus medius and minimus) and external rotators (piriformis, gemelli, obdurators) Mechanism • Isolated greater trochanter fracture may be related to impaction from fall, versus avulsion Imaging • If incomplete, obtain MRI to assess extent of fracture Management • Most heal well with nonoperative management • If significant displacement, then ORIF Disclosures Learning Objectives Organization Anatomy Imaging Osteochondral Subchondral Femoral Neck Intertrochanteric Greater Troch. Lesser Troch. Subtrochanteric Conclusion References
  • 31. Lesser Trochanter Fracture Anatomy • Lesser trochanter is attachment site for iliopsoas Mechanism • Fracture may be due to avulsion • In the absence of injury, isolated lesser trochanter fracture is highly suspicious for an underlying malignancy Imaging • Obtain MRI to assess extent of fracture • Evaluate for underlying malignancy Management • Nondisplaced fractures heal well with nonoperative management • If significantly displaced, then ORIF James SL et al. Eur Radiol 2006 Mildly displaced lateral trochanter fracture in a patient with prostate cancer and diffuse blastic metastases. Also note the extensive periosteal reaction. Disclosures Learning Objectives Organization Anatomy Imaging Osteochondral Subchondral Femoral Neck Intertrochanteric Greater Troch. Lesser Troch. Subtrochanteric Conclusion References
  • 32. Subtrochanteric and Proximal Femoral Shaft: Traumatic Versus Atypical Fractures Shane E et al. J Bone Miner Res 2010. Park-Wyllie LY et al. JAMA 2011 Atypical Fractures Long-term bisphosphonate usage, o/minimal trauma Imaging Typically subtrochanteric or femoral shaft Transverse or short oblique orientation Lateral beaking (arrow) Normal bone mineral density Management Evaluate contralateral femur Treat with ORIF, intramedullary nail and screw0 It is important for the radiologist to recognize the different patterns of traumatic and atypical subtrochanteric and proximal shaft fractures Disclosures Learning Objectives Organization Anatomy Imaging Osteochondral Subchondral Femoral Neck Intertrochanteric Greater Troch. Lesser Troch. Subtrochanteric Conclusion References Typical Fractures Often traumatic, high impact Imaging Radiographs generally diagnostic Oblique or spiral in orientation Proximal piece is flexed, abducted, and externally rotated MR/CT if concern for pathologic fracture Management ORIF Higher rates of failure due to high stress anatomy
  • 33. Conclusion • Proximal femoral fractures can be classified as femoral head, intracapsular, and extracapsular • Increased concern for AVN and nonunion for intracapsular fractures due to vascular compromise • Important to understand how imaging features reflect underlying mechanical forces and mechanisms of injury, and how these in turn guide management • If a patient has hip pain and negative x-rays, strongly consider further imaging with MRI Disclosures Learning Objectives Organization Anatomy Imaging Osteochondral Subchondral Femoral Neck Intertrochanteric Greater Troch. Lesser Troch. Subtrochanteric Conclusion References
  • 34. References • Trueta J, Harrison MH. The normal vascular anatomy of the femoral head in adult man. J Bone Joint Surg Br. 1953;35:442-61 • Ly TV, Swiontkowski MF. Treatment of femoral neck fractures in young adults. J Bone Joint Surg Am. 2008;90:2. 254-66 • Byrne DP et al. The Open Sports Medicine Journal 2010;4;51-7. • Bowman KF Jr, Fox J, Sekiya JK. A clinically relevant review of hip biomechanics. Arthroscopy 2010;26(8):1118-29. • Dominguez S, Liu P, Roberts C et al. Prevalence of traumatic hip and pelvic fractures in patients with suspected hip fracture and negative initial standard radiographs—a study of emergency department patients. Acad Emerg Med 2005;12(4):366-9. • Frihagen F, Nordsletten L, Tariq R, et al. MRI diagnosis of occult hip fractures. Acta Orthop 2005;76(4):524-30. • Kirby MW, Spritzer C. Radiographic detection of hip and pelvic fractures in the emergency department. AJR Am J Roentgenol 2010;194(4):1054-60. • Khurana B, Okanobo H, Ossiani M, et al. Abbreviated MRI for patients presenting to the emergency department with hip pain. AJR Am J Roentgenol 2012;198(6):581-8. • Ross JR, Gardner MJ. Femoral head fractures. Curr Rev Musculoskelet Med 2012;5(3):199-205. • Rockwood and Green’s Fractures in Adults, 7th Edition. Wolters Kluwer/Lippincott Williams & Wiilkins, New York, 2010. • Yamamoto T. Subchondral insufficiency fractures of the femoral head. Clin Orthop Surg. 2012:4(3):173-80. • Ikemura S, Yamamoto T, Motomura G, et al. MRI evaluation of collapsed femoral heads in patients 60 years old or older: differentiation of subchondral insufficiency fracture from osteonecrosis of the femoral head. AJR Am J Roentgenol 2010;195:W63-W68. • Frandsen PA, Andersen PE Jr, Christoffersen H et al. Osteosynthesis of femoral neck fracture. The sliding-screw-plate with or without compression. Acta Orthop Scand 1984;55(6):620-3. • Kreder HJ. Arthroscopy led to fewer failures and more complications than did internal fixation for displaced fractures of the femoral neck. J Bone Joint Surg Am 2002;84:2108. • Miller BJ, Lu X, Cram P. The Trends in Treatment of Femoral Neck Fractures in the Medicare Population from 1991 to 2008. J Bone Joint Surg Am 2013:95(18):1-8. • Goh SK, Samuel M, Su DHC et al. Meta-analysis comparing total hip arthroplasty with hemiarthroplasty in the treatment of displaced neck of femur fracture. J Arthroplasty. 2009:24(13):400-6. • Koval KJ, Zuckerman JD. Hip fractures, II: evaluation and treatment of intertrochanteric fractures. J Am Acad Orthop Surg 1994;2(3):150-6. • Trafton PG. Subtrochanteric-intertrochanteric femoral fractures. Orthop Clin North Am 1987;18(1):59-71. • Su BW, Heyworth BE, Protopsaltis TS et al. Basicervical versus intertrochanteric fractures: an analysis of radiographic and functional outcomes. Orthopedics 2006;29(10):919-25. • Forte ML, Vimig BA, Kane RL. Geographic variation in device use for intertrochanteriic hif fractures. J Bone Joint Surg Am 2008;90(4):691-9. • James Sl, Davies Am. Atraumatic avulsion of the lesser trochanter as an indicator of tumour infiltration. Eur Radiol. 2006;16(2):512-4 • Shane E, Burr D, Ebeling PR et al. Atypical subtrochanteric and diaphyseal femoral fractures: report of a task force of the American Society of Bone and Mineral Research 2010; 25(11):2267-94 • Park-Wyllie LY, Mamdani MM, Juurlink DN. Bisphosphonate use and the risk of subtrochanteric or femoral shaft fractures in older women. JAMA 2011;305(8):783-9. • Tornetta P III. Subtrochanteric femur fracture. J Orthop Trauma 2002;16(4);280-3 Thank You For Viewing Our Exhibit – Jeffrey Shyu (jshyu@partners.org) Disclosures Learning Objectives Organization Anatomy Imaging Osteochondral Subchondral Femoral Neck Intertrochanteric Greater Troch. Lesser Troch. Subtrochanteric Conclusion References

Hinweis der Redaktion

  1. Trueta J, Harrison MH. The normal vascular anatomy of the femoral head in adult man. J Bone Joint Surg Br. 1953;35-442-61 Ly TV, Swiontkowski MF. Treatment of femoral neck fractures in young adults. J Bone Joint Surg Am. 2008;90:2. 254-66
  2. 24877631 F01136644 03233905 20025920
  3. 24877631 F01136644 03233905 20025920
  4. chart Miller BJ, Lu X, Cram P. The Trends in Treatment of Femoral Neck Fractures in the Medicare Population from 1991 to 2008. J Bone Joint Surg Am 2013:95(18):1-8. Goh SK, Samuel M, Su DHC et al. Meta-analysis comparing total hip arthroplasty with hemiarthroplasty in the treatment of displaced neck of femur fracture. J Arthroplasty. 2009:24(13):400-6. Cserhati P, Kazar G, Manninger J, Fekete k, Frenyo S. Non-operative or operative treatment for undisplaced femoral neck fractures: a comparative study of 122 non-operative and 125 operatively treated cases. Injury 1996;27;8:583-8.
  5. Miller BJ, Lu X, Cram P. The Trends in Treatment of Femoral Neck Fractures in the Medicare Population from 1991 to 2008. J Bone Joint Surg Am 2013:95(18):1-8. Sliding hip screw for nondisplaced fx
  6. F00495342 Su BW, Heyworth BE, Protopsaltis TS et al. Basicervical versus intertrochanteric fractures: an analysis of radiographic and functional outcomes. Orthopedics 2006;29;10:919-25.
  7. James Sl, Davies Am. Atraumatic avulsion of the lesser trochanter as an indicator of tumour infiltration. Eur Radiol. 2006 16(2):512-4
  8. Park-Wyllie LY, Mamdani MM, Juurlink DN. Bisphosphonate use and the risk of subtrochanteric or femoral shaft fractures in older women. JAMA 2011;305(8):783-9.