1. By: Hamza AlGhamdi

2. NORMAL KIDNEY’S PHYSIOLOGY AND HISTOLOGY

3. Capillary Space Endothelium Urinary Space GBM Podocyte

4. NORMAL KIDNEY HISTOLOGY

5. Parietal Epithelium Visceral Epithelium Capillary Lumen Mesangial Cell Basement Membrane (GBM) Urinary Space RBC Endothelial Cell

6. NEPHROTIC SYNDROME IS NOT A DISEASE

8. Periorbital edema Pitting edema of lower limbs

18. Membranous GN Sub-epithelial immune Complex deposits Thickened GBM

19. Membranous GN H&E

20. Membranous GN IF

21. Capillary Lumen GBM GBM Membranous GN EM

24. MINIMAL CHANGE DISEASE Foot Process Fusion

29. FSGS H&E

32. Figure 8. Pathology of membranoproliferative glomerulonephritis type I. (a) Light microscopy shows a hypercellular glomerulus with accentuated lobular architecture and a small cellular crescent (methenamine silver).

35. THANK YOU Powerpoint presentation