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Cranial nerve
examination
Cranial nerves
I.
II.
III.
IV.
V.
VI.
VII.
VIII.
IX.
X.
XI.
XII.

Olfactory
Optic
Occulomotor
Trochlear
Trigeminal
Abducent
Facial
Auditory
Glossopharyngeal
Vagus
Spinal accessory
Hypoglosseal
Summary of funCtion of Cranial
nerveS
FUNCTIONAL TYPES
Pure sensory




Pure motor

Olfactory
Optic



Auditory







Trochlear
Abducent
Accessory
Hypoglosseal

Mixed nerves






Trigeminal
Facial
Glossopharyngeal
Vagus
Occulomotor
Cranial Nerve I: Olfactory
Function
 Carries

the sensation of smell from nasal
mucosa to olfactory bulb
Purpose of the test
 To

determine any impairment of smell is
unilateral or bilateral
 Whether impairment is due to any local nasal
disease or neural lesion
Method of testing
 Small

bottles containing
essences of very familiar
odour are required
• Coffee
• Lemon
• Chocolate
• Asafetida etc
PROCEDURE
Compress 1 nostril & sniff the taste odour twice

Ask whether he can smell or identify odour

Repeat test on other nostril & ask if smell
is similar in both nostril
Allow odour to disperse & repeat test with other
2 test odour, ask he can distinguish smell
Interpretation of result




Who can recognize & name odours quickly (females)
Who can recognize but difficult in naming (males)
Who can smell & know difference but neither recognize
nor naming

•





The above 3 should be accepted as normal

Who feel each odour is similar but is distorted &
unpleasant (parosmia)
Those who cant smell anything or is much reduced
compared to the other (anosmia)
Those whose responses are vague & variable
Common causes of anosmia
 Acute/chronic

inflammatory nasal disease
 Heavy smoking
 Head injury
 Intra cranial tumour compressing the
olfactory bulb
 Atrophy of olfactory bulb
 Chronic meningeal inflammation
 Parkinson’s disease
Cranial Nerve II: Optic
Function
 Carries

the visual impulses from the retina to
the optic chiasma & in the optic tract to the
lateral geniculate body
 The impulse acts as an afferent pathway for
the pupillary light reflex
Purpose of the test
 To

measure aquity of vision & determine if
any disease is due to local occular disease or
neural impairment
 To chart the visual field
Method of testing
 Visual

acuity

• The standard snellen’s

chart can be used for vision
& the Jaegar type card can
be used for near vision
[the commonest causes of
visual error lies in the eye only]
Visual field
 Purpose:

• To chart periphery of visual field
• To detect position, size & shape of the blind spot
Confrontation test
Pt & examiner sit face to face

Pt covers left eye & examiner right

PT moves the test object from outside the
visual field towards midline
Instruct Pt to indicate appearance of
the object
Common causes
 Total

unilateral loss of vision: optic nerve
lesion
 Homonymous hemianopia: lesion between
optic tract to occipital cortex
 Bitemporal hemianopia: lesion of optic
chiasma
Occulomotor, Trochlear, Abducent
Function
 Controls

the external occular muscles &
elevators of the lids
 Also regulates the pupillary muscles
Purpose of the test
 Inspect

pupils to rule out a local disease,
peripheral lesion or a nuclear involvement
 Examine eye movement & determine if
defects is muscular origin or neural
involvement
 To detect nystagmus
Method of testing
 Observation

• Presence & absence of ptosis & squint
• Whether unilateral or bilateral
• Constant or variable
• Size, shape, equality & regularity of the pupils
Reaction to light
 Reduce

illumination of room & vision
should focus on a far object
 A bright beam of light is shone from the side
of one eye
 Repeat on the other side
[the pupil should constrict briskly]
 Shield one eye & perform test on the other
& see for consensual reaction
Reaction to convergence &
accommodation for near vision
 Fix

vision on a distant object & instruct to
look in a near object
 Place finger tip in front of the bridge of the
nose (22 cm)
 Then return to the far object
 Observe pupillary reaction in both
Examination of occular movement
 Observe

lagging of one
or both eye

• Observe nystagmus
Analysis of diplopia
 Shield

one eye with a transparent red shield
 Object is moved from left to right, up & down
 Ask if -

• He sees 1 or 2 object
• Object lies one above the other or side by side
Rules governing analysis of diplopia
 Separation

of image is greatest in the
direction in which the weak muscle has its
purest action
 False image is displaced farthest in the
direction in which the weak muscle should
move the eye
Analyzing nystagmus
 Watch

the patients eye while talking
 Ask to look at a definite point & move the
point from left to right & up to down
 Hold each end position for 5 sec & assess
nystagmus (direction, rate amplitude)
Common causes of paralysis
Pontine lesions
 Neoplasms
 Vascular accidents
 Demyelinating disease
 Meningeal inflammation
 Tumour of base of skull
 Increased intra cranial pressure
 Head injury
[Total paralysis of III, IV & VI nerve indicates a lesion in
cavernous sinus (carotid aneurism)]

Cranial Nerve V: Trigeminal
Function
 Carries

all forms of sensation from the face,
anterior scalp,eye & the anterior 3rd of the
tongue
 Also supplies the muscles of mastication
Purpose of the test
 To

determine any sensory impairment
 To determine unilateral or bilateral motor
weakness & determine UMN from LMN
Method of examination
 Superficial

sensory asst from mainly 6 areas
(mainly light touch & pain)

• Forehead & upper part of the side of nose

(ophthalmic)
• Malar & upper lip region (maxillary)
• Chin & anterior part of tongue (mandibular)
Interpretation
 Total

loss of sensation: lesion of ganglion or
sensory root
 Total sensory loss over 1 division: partial
lesion of ganglion or root
 Touch only lost: pontine lesion affecting
sensory nucleus
 Pain & temp lost: dissociate anesthesia
(seringobulbia)
Corneal reflex
 Using

a cotton piece the
cornea is teased
 Normal response is a
bilateral blink
(facial nerve forms the
efferent loop of the reflex arc)
Interpretation
 No

closure: ophthalmic division of the facial
nerve
 No response in either lid when abn. is tested
& bilateral blink when normal is tested: V
nerve lesion
 No response of the affected side whichever
side is tested: VII nerve lesion
Motor assessment
Muscles of mastication
 Have Pt bite against resistance
 Have Pt protrude mandible
against resistance
 Have Pt go into lateral
excursive movts against
resistance
 Jaw jerk

Common causes
 Tumours

of base of skull
 Chronic meningeal lesion
 Trigeminal sensory neuropathy
 Acoustic neuroma
 Syringomyelia
 Multiple sclerosis
Cranial Nerve VII: Facial
Function
 Supplies

the muscles of facial expression
including platysma & stapedius muscle
 Secretomotor fibers to the lacrimal gland &
the salivary gland
 Carries sensation of taste from anterior 2/3
of tongue & general sensation from external
acoustic meatus
Purpose of the test
 To

detect any unilateral or bilateral
weakness of facial muscles (UMN or LMN)
 Detect impairment of taste
Method of testing
 Observation

• Symmetry and asymmetry of
•

face
Nasolabial fold & wrinkle on
forehead

 Ask

the Pt to close the
eyes, raise the eyebrows,
blow out the cheek,
whistle etc
Examination of taste
 The

four primary taste (sweet, salt, sour,
bitter) can be carried out by using sugar,
salt, vinegar & quinine
 The side of the tongue is moistened by the
test substance
 Ask the Pt to indicate taste by pointing
Secretomotor function
 The

flow of tears of two side can be
compared by giving ammonia to inhale
which will result in tearing of eye
 The flow of saliva can be tasted by keeping a
spicy substance in the tongue & the tip is
raised to observe the sub maxillary salivary
flow
Reflexes
 Corneal

reflex
 Nasopalpebral reflex: tap on the
nasopalpebral ridge will produce
closure of both eyes. In bells palsy
there is failure to close on the
affected side
Common causes of facial paralysis
 Neoplasm

affecting thalamus: unilateral
emotional paralysis
 Parkinsonism : bilateral emotional paralysis
 CVA neoplasm, MND: bilateral UMN palsy
 Bell’s palsy
 GBS
Cranial Nerve VIII: Vestibulocochlear
Function
 Carries

the impulses of sound from the hair
cell of organ of corti to cochlear nucleus in
pons
 Control balance through vestibular nerve
Purpose of the test
 To

determine any deafness is bilateral or
unilateral
 Whether deafness is due disease of middle
ear or cochlear nerve
 To determine the disturbance of vestibular
functions
Test of hearing
 Observe

if the patient turns
one ear towards you
 Evaluate hearing using a
ticking watch, rub fingers
together, whisper.
Rinne’s test
 Strike

a tuning fork gently, hold it near one
external meatus & ask the Pt if he can hear it
 Place it on the mastoid, ask if he can still
hear it & instruct him to say “NOW” when
sound ceases, & keep it on the external
meatus again (normally the note is still
audible)
Interpretation
 In

middle ear deafness – the note is not heard
 In nerve deafness – air & bone conduction
are reduced but air remains better
Weber’s test
 The

fork is place on the vertex
 Ask the Pt if he can hear the sound all over
the head, in both ears or in one ear
 In nerve deafness the sound appear to be
heard on the normal ear
 On chronic middle ear disease it is conducted
to the abnormal ear
Common causes of deafness
 Disease

of external & middle ear &
Eustachian tube
 Prolonged exposure to loud noise
 Old age
 Meningitis
 Demyelinating disease
 Deafness due to drugs
Test of vestibular function
 Observe

equilibrium as patient
walks or stands
 Observe abnormal eye movts
 Ask for -

• Dizziness
• Falling
• Nausea and vomiting
Cranial Nerve IX: Glossopharyngeal
Function
General Sensory: posterior 1/3
of tongue, tonsil, skin of
external ear, tympanic
membrane & pharynx

Visceral Sensory:
subconscious sensation
from carotid body & sinus

Visceral Motor:
parasympathetic stimulation of
parotid gland, & controls blood
vessels in carotid body

Special Sensory: carries
taste from posterior 1/3
of tongue

Branchial Motor:
Supplies styolopharyngeus
muscle
Cranial Nerve X: Vagus
Function
General Sensory: posterior meninges,
concha, skin at back of ear, external
tympanic membrane, pharynx &
larynx
Visceral Motor: parasympathetic
stimulation to smooth muscle &
glands of pharynx, larynx; thoracic
& abdominal viscera & cardiac
muscle

Visceral Sensory: from larynx,
trachea, esophagus, & thoracic &
abdominal viscera, stretch
receptors & chemoreceptors

Motor: superior, middle, inferior
constrictors; levator palati,
salpingopharyngeus,
palatopharyngeus, palatoglossus
Purpose of the test
 To

test the elevation of palate & contraction
of pharynx
 To examine the movts of vocal cords
[note: the IX & X nerve are tested together]
Method of testing
 Notice

the pitch & quality of voice, cough &
difficulty in swallowing saliva
 Ask the Pt to open his mouth wide after a few
movts ask to say “AH” while breathing out &
“UGH” while in
 The palate should move symmetrically upwards
& backwards, the uvula in mid line & two sides
of pharynx contract symmetrically
Common causes of lesion
 Poliomyelitis
 Syringobulbia
 Posterior

fossa tumor
 Advanced parkinsonism
 Myasthenia gravis
 Enlarged cervical glands
 Surgical operation of the neck
Cranial Nerve XI: Accessory
Function
Supplies
sternocleidomastoid
& trapezius muscles
Purpose of the test
 To

detect wasting & weakness, unilateral or
bilateral of the muscles
Method of testing
Common causes of paralysis
 MND
 Poliomyelitis
 Polyneuropathy
 Trauma

in the neck or base of skull
 Tumour at jugular foramen
 Syringomyelia
Cranial Nerve XII: Hypoglossal
Function
 Control

movts of the tongue, hyoid bone &
larynx during & after deglutition
Supplies 3 of 4 extrinsic
muscles of tongue &
all intrinsic muscles of
tongue
Purpose of the test
 To

inspect the surface of the tongue
 To detect wasting, weakness & involuntary
movts
 To examine voluntary muscle control
Method of testing
 Ask

the Pt to protrude the
tongue & observe for

• Reduction in size of affected side
• Excessive ridging & wrinkling
• Restricted protrusion
• Deviation towards one side
Common lesions
 Syringomyelia
 Poliomyelitis
 MND
 Profound
 ALS

hemiplegia
13th Cranial nerve
 Known

as cranial nerve zero or Terminal

Nerve
 It projects from nasal cavity, enters
brain just a little bit ahead of other
cranial nerves as a microscopic plexus of
unmyelinated peripheral nerve fascicles
FunCtion
 The

nerve is vestigial or related to
sensing of pheromones
 Regulates sexual behavior in mammals

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Cranial nerve examination

  • 3. Summary of funCtion of Cranial nerveS
  • 4. FUNCTIONAL TYPES Pure sensory    Pure motor Olfactory Optic  Auditory    Trochlear Abducent Accessory Hypoglosseal Mixed nerves      Trigeminal Facial Glossopharyngeal Vagus Occulomotor
  • 5. Cranial Nerve I: Olfactory
  • 6. Function  Carries the sensation of smell from nasal mucosa to olfactory bulb
  • 7. Purpose of the test  To determine any impairment of smell is unilateral or bilateral  Whether impairment is due to any local nasal disease or neural lesion
  • 8. Method of testing  Small bottles containing essences of very familiar odour are required • Coffee • Lemon • Chocolate • Asafetida etc
  • 9. PROCEDURE Compress 1 nostril & sniff the taste odour twice Ask whether he can smell or identify odour Repeat test on other nostril & ask if smell is similar in both nostril Allow odour to disperse & repeat test with other 2 test odour, ask he can distinguish smell
  • 10. Interpretation of result    Who can recognize & name odours quickly (females) Who can recognize but difficult in naming (males) Who can smell & know difference but neither recognize nor naming •    The above 3 should be accepted as normal Who feel each odour is similar but is distorted & unpleasant (parosmia) Those who cant smell anything or is much reduced compared to the other (anosmia) Those whose responses are vague & variable
  • 11. Common causes of anosmia  Acute/chronic inflammatory nasal disease  Heavy smoking  Head injury  Intra cranial tumour compressing the olfactory bulb  Atrophy of olfactory bulb  Chronic meningeal inflammation  Parkinson’s disease
  • 13. Function  Carries the visual impulses from the retina to the optic chiasma & in the optic tract to the lateral geniculate body  The impulse acts as an afferent pathway for the pupillary light reflex
  • 14. Purpose of the test  To measure aquity of vision & determine if any disease is due to local occular disease or neural impairment  To chart the visual field
  • 15. Method of testing  Visual acuity • The standard snellen’s chart can be used for vision & the Jaegar type card can be used for near vision [the commonest causes of visual error lies in the eye only]
  • 16. Visual field  Purpose: • To chart periphery of visual field • To detect position, size & shape of the blind spot
  • 17. Confrontation test Pt & examiner sit face to face Pt covers left eye & examiner right PT moves the test object from outside the visual field towards midline Instruct Pt to indicate appearance of the object
  • 18. Common causes  Total unilateral loss of vision: optic nerve lesion  Homonymous hemianopia: lesion between optic tract to occipital cortex  Bitemporal hemianopia: lesion of optic chiasma
  • 20. Function  Controls the external occular muscles & elevators of the lids  Also regulates the pupillary muscles
  • 21. Purpose of the test  Inspect pupils to rule out a local disease, peripheral lesion or a nuclear involvement  Examine eye movement & determine if defects is muscular origin or neural involvement  To detect nystagmus
  • 22. Method of testing  Observation • Presence & absence of ptosis & squint • Whether unilateral or bilateral • Constant or variable • Size, shape, equality & regularity of the pupils
  • 23. Reaction to light  Reduce illumination of room & vision should focus on a far object  A bright beam of light is shone from the side of one eye  Repeat on the other side [the pupil should constrict briskly]  Shield one eye & perform test on the other & see for consensual reaction
  • 24. Reaction to convergence & accommodation for near vision  Fix vision on a distant object & instruct to look in a near object  Place finger tip in front of the bridge of the nose (22 cm)  Then return to the far object  Observe pupillary reaction in both
  • 25. Examination of occular movement  Observe lagging of one or both eye • Observe nystagmus
  • 26. Analysis of diplopia  Shield one eye with a transparent red shield  Object is moved from left to right, up & down  Ask if - • He sees 1 or 2 object • Object lies one above the other or side by side
  • 27. Rules governing analysis of diplopia  Separation of image is greatest in the direction in which the weak muscle has its purest action  False image is displaced farthest in the direction in which the weak muscle should move the eye
  • 28. Analyzing nystagmus  Watch the patients eye while talking  Ask to look at a definite point & move the point from left to right & up to down  Hold each end position for 5 sec & assess nystagmus (direction, rate amplitude)
  • 29. Common causes of paralysis Pontine lesions  Neoplasms  Vascular accidents  Demyelinating disease  Meningeal inflammation  Tumour of base of skull  Increased intra cranial pressure  Head injury [Total paralysis of III, IV & VI nerve indicates a lesion in cavernous sinus (carotid aneurism)] 
  • 30. Cranial Nerve V: Trigeminal
  • 31. Function  Carries all forms of sensation from the face, anterior scalp,eye & the anterior 3rd of the tongue  Also supplies the muscles of mastication
  • 32. Purpose of the test  To determine any sensory impairment  To determine unilateral or bilateral motor weakness & determine UMN from LMN
  • 33. Method of examination  Superficial sensory asst from mainly 6 areas (mainly light touch & pain) • Forehead & upper part of the side of nose (ophthalmic) • Malar & upper lip region (maxillary) • Chin & anterior part of tongue (mandibular)
  • 34. Interpretation  Total loss of sensation: lesion of ganglion or sensory root  Total sensory loss over 1 division: partial lesion of ganglion or root  Touch only lost: pontine lesion affecting sensory nucleus  Pain & temp lost: dissociate anesthesia (seringobulbia)
  • 35. Corneal reflex  Using a cotton piece the cornea is teased  Normal response is a bilateral blink (facial nerve forms the efferent loop of the reflex arc)
  • 36. Interpretation  No closure: ophthalmic division of the facial nerve  No response in either lid when abn. is tested & bilateral blink when normal is tested: V nerve lesion  No response of the affected side whichever side is tested: VII nerve lesion
  • 37. Motor assessment Muscles of mastication  Have Pt bite against resistance  Have Pt protrude mandible against resistance  Have Pt go into lateral excursive movts against resistance  Jaw jerk 
  • 38. Common causes  Tumours of base of skull  Chronic meningeal lesion  Trigeminal sensory neuropathy  Acoustic neuroma  Syringomyelia  Multiple sclerosis
  • 40. Function  Supplies the muscles of facial expression including platysma & stapedius muscle  Secretomotor fibers to the lacrimal gland & the salivary gland  Carries sensation of taste from anterior 2/3 of tongue & general sensation from external acoustic meatus
  • 41. Purpose of the test  To detect any unilateral or bilateral weakness of facial muscles (UMN or LMN)  Detect impairment of taste
  • 42. Method of testing  Observation • Symmetry and asymmetry of • face Nasolabial fold & wrinkle on forehead  Ask the Pt to close the eyes, raise the eyebrows, blow out the cheek, whistle etc
  • 43. Examination of taste  The four primary taste (sweet, salt, sour, bitter) can be carried out by using sugar, salt, vinegar & quinine  The side of the tongue is moistened by the test substance  Ask the Pt to indicate taste by pointing
  • 44. Secretomotor function  The flow of tears of two side can be compared by giving ammonia to inhale which will result in tearing of eye  The flow of saliva can be tasted by keeping a spicy substance in the tongue & the tip is raised to observe the sub maxillary salivary flow
  • 45. Reflexes  Corneal reflex  Nasopalpebral reflex: tap on the nasopalpebral ridge will produce closure of both eyes. In bells palsy there is failure to close on the affected side
  • 46. Common causes of facial paralysis  Neoplasm affecting thalamus: unilateral emotional paralysis  Parkinsonism : bilateral emotional paralysis  CVA neoplasm, MND: bilateral UMN palsy  Bell’s palsy  GBS
  • 47. Cranial Nerve VIII: Vestibulocochlear
  • 48. Function  Carries the impulses of sound from the hair cell of organ of corti to cochlear nucleus in pons  Control balance through vestibular nerve
  • 49. Purpose of the test  To determine any deafness is bilateral or unilateral  Whether deafness is due disease of middle ear or cochlear nerve  To determine the disturbance of vestibular functions
  • 50. Test of hearing  Observe if the patient turns one ear towards you  Evaluate hearing using a ticking watch, rub fingers together, whisper.
  • 51. Rinne’s test  Strike a tuning fork gently, hold it near one external meatus & ask the Pt if he can hear it  Place it on the mastoid, ask if he can still hear it & instruct him to say “NOW” when sound ceases, & keep it on the external meatus again (normally the note is still audible)
  • 52. Interpretation  In middle ear deafness – the note is not heard  In nerve deafness – air & bone conduction are reduced but air remains better
  • 53. Weber’s test  The fork is place on the vertex  Ask the Pt if he can hear the sound all over the head, in both ears or in one ear  In nerve deafness the sound appear to be heard on the normal ear  On chronic middle ear disease it is conducted to the abnormal ear
  • 54. Common causes of deafness  Disease of external & middle ear & Eustachian tube  Prolonged exposure to loud noise  Old age  Meningitis  Demyelinating disease  Deafness due to drugs
  • 55. Test of vestibular function  Observe equilibrium as patient walks or stands  Observe abnormal eye movts  Ask for - • Dizziness • Falling • Nausea and vomiting
  • 56. Cranial Nerve IX: Glossopharyngeal
  • 57. Function General Sensory: posterior 1/3 of tongue, tonsil, skin of external ear, tympanic membrane & pharynx Visceral Sensory: subconscious sensation from carotid body & sinus Visceral Motor: parasympathetic stimulation of parotid gland, & controls blood vessels in carotid body Special Sensory: carries taste from posterior 1/3 of tongue Branchial Motor: Supplies styolopharyngeus muscle
  • 59. Function General Sensory: posterior meninges, concha, skin at back of ear, external tympanic membrane, pharynx & larynx Visceral Motor: parasympathetic stimulation to smooth muscle & glands of pharynx, larynx; thoracic & abdominal viscera & cardiac muscle Visceral Sensory: from larynx, trachea, esophagus, & thoracic & abdominal viscera, stretch receptors & chemoreceptors Motor: superior, middle, inferior constrictors; levator palati, salpingopharyngeus, palatopharyngeus, palatoglossus
  • 60. Purpose of the test  To test the elevation of palate & contraction of pharynx  To examine the movts of vocal cords [note: the IX & X nerve are tested together]
  • 61. Method of testing  Notice the pitch & quality of voice, cough & difficulty in swallowing saliva  Ask the Pt to open his mouth wide after a few movts ask to say “AH” while breathing out & “UGH” while in  The palate should move symmetrically upwards & backwards, the uvula in mid line & two sides of pharynx contract symmetrically
  • 62. Common causes of lesion  Poliomyelitis  Syringobulbia  Posterior fossa tumor  Advanced parkinsonism  Myasthenia gravis  Enlarged cervical glands  Surgical operation of the neck
  • 63. Cranial Nerve XI: Accessory
  • 65. Purpose of the test  To detect wasting & weakness, unilateral or bilateral of the muscles
  • 67. Common causes of paralysis  MND  Poliomyelitis  Polyneuropathy  Trauma in the neck or base of skull  Tumour at jugular foramen  Syringomyelia
  • 68. Cranial Nerve XII: Hypoglossal
  • 69. Function  Control movts of the tongue, hyoid bone & larynx during & after deglutition Supplies 3 of 4 extrinsic muscles of tongue & all intrinsic muscles of tongue
  • 70. Purpose of the test  To inspect the surface of the tongue  To detect wasting, weakness & involuntary movts  To examine voluntary muscle control
  • 71. Method of testing  Ask the Pt to protrude the tongue & observe for • Reduction in size of affected side • Excessive ridging & wrinkling • Restricted protrusion • Deviation towards one side
  • 72. Common lesions  Syringomyelia  Poliomyelitis  MND  Profound  ALS hemiplegia
  • 73. 13th Cranial nerve  Known as cranial nerve zero or Terminal Nerve  It projects from nasal cavity, enters brain just a little bit ahead of other cranial nerves as a microscopic plexus of unmyelinated peripheral nerve fascicles
  • 74. FunCtion  The nerve is vestigial or related to sensing of pheromones  Regulates sexual behavior in mammals