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Borderline
     Personality
      Disorder
                Prof. Amany Haroun El Rasheed
                        Ain Shams Univ., Cairo, Egypt
                             M.N.P., D.P.P., M.D.
               Master in Mental Hygiene (Johns Hopkins Univ.)
Fellowship in Substance Abuse Treatment & Prevention (Johns Hopkins Univ.)
                              APA Membership
                             ISAM Membership
                              WPA Fellowship
                                 FRC Psych
What is a healthy personality?
 SHORT    FORMULA:
 ability to enjoy, to relate and to work.

 Psychologically healthy with a positive
 development is a person who is able
 to utilize eight aspects or polarities –
 depending on life context or
 requirement – in a way that is
 situational or functional. (Fiedler)
Eight Modalities of Personal Functioning

  Individuality, Independence.
  Relationship, Attachment, Security.
  Spontaneity, Desire for New Experiences.
  Stability, Self control.
  Wellbeing, Pleasure.
  Allowing and accepting pain, Melancholy
  Actively structuring life − Manipulation.
  Passive Receiving, letting things happen.
Common Themes in Normality
 strength of character    ability to experience
 ability to learn from     pleasure without
  experience                conflict
 ability to work          flexibility/ability to

 ability to achieve        adjust
  insight                  ability to laugh

 absence of               ability to love another
  symptoms/conflict        degree of
                            acculturation
Where is the line?
 It’s all a matter of degree and which
  traits:
e.g. To be a successful pilot, a person
  must have a degree of narcissism
  (healthy sense of self-confidence) and
  obsessive compulsive (attention to
  detail, conscientious).
See the whole person
 Therefore,don’t rely on a single, “slice-
 in-time” conclusion when considering
 traits

 The   most normal person can
 look pretty disordered at times when
 stressed
Characteristics of Personality
                Disorders
   An enduring pattern of inner experience
    and behavior that deviates markedly from the
    expectations of the individual’s culture,
   is pervasive and inflexible,
   has an onset in adolescence or early
    adulthood,
   is stable over time,
   and leads to distress or impairment.
Personality Disorders: Facts and Statistics

   Prevalence of Personality Disorders
       About 0.5% to 2.5% of the general population
       Rates are higher in inpatient and outpatient settings


   Gender Distribution and Gender Bias in
    Diagnosis
       Gender bias exists in the diagnosis of personality
        disorders
       Such bias may be a result of criterion or
        assessment gender bias
Personality Disorders:
             Facts and Statistics
 Originsand Course of Personality
 Disorders
     Thought to begin in childhood
     Tend to run a chronic course if untreated



 Co-Morbidity    Rates                           are   High
 (depression, anxiety)
Personality Disorders: Facts and
                 Statistics

   Rates of personality disorder in the general
    population (Coid et al 2006) - 4-5%

    Rates of personality disorder in young adults,
    24-25 years old (Moran et al 2006) – 18.6%

   Rates of personality disorder among self-
    harm patients (Haw et al 2001) – 47%
What is Personality?
 Personality lies along a continuum from
  healthy to pathological

 Itis founded on particular adaptations
  or arrests at various stages along the
  developmental path
Character structures/personality
             traits
   Result in distinct clusters of defenses,
    character structures, or personality traits

   These persist over time, become internalised
    and repeat as scripts

   They serve to assist us in managing anxiety
    and self-esteem
Character structures/Personality Traits

Enduring patterns of:
 Perceiving
 Relating to
 Thinking    about oneself and the
  environment
 In a wide range of social and personal
  contexts
Not accounted for by:
 Culture
 Religious beliefs
 Immigration
 Stressful events
 Axis I disorders
 Medical condition
 Communication, autistic or developmental
  disorder
Effects
Two or more of the following:
 Cognition
 Affectivity
 Interpersonal functioning
 Impulse control
Functional Assessment
 Motivation - What is wished for, feared,
  valued?
 Cognitive functioning - functioning, style,
  coherence, belief systems
 Affective functioning - intensity, lability,
  experience of affect, capacity for ambivalence
 Affect regulation - coping strategies,
  defenses, repertoire
Functional Assessment
 Experience of self - continuity, coherence,
  agent, self-esteem, ideals, self presentation,
  identity
 Experience of others - wishes, fears,
  schemas
 Capacity for relatedness
 Management of aggression
 Emotional developmental history
When is personality pathological?
 Where    defenses become so rigid and
  inflexible that they are not adaptive

 Reality   is distorted

 Psychological    growth is prevented

 NB   These were adaptive in early life
Personality Disorder Clusters
 Personality  disorders               fall    into     three
 general clusters:
   Persons         in cluster A seem odd or
    eccentric
        Paranoid, schizoid, schizotypal
   Persons  in cluster B seem dramatic,
    emotional or erratic
        Antisocial, borderline, histrionic, narcissistic
   Persons       in cluster C appear as anxious or
    fearful
        Avoidant, dependent, obsessive-compulsive
Dimensions
                Dsm-iv:
    Emotional   Cluster A – Odd or eccentric cluster (e.g.,
    Dramatic    paranoid, schizoid)
                Cluster B – Dramatic, emotional, erratic
                cluster (e.g., antisocial, borderline)
                Cluster C – Fearful or anxious cluster (e.g.,
                avoidant, obsessive-compulsive)




                   oDD
                   ExcEntric

                                                 anxious
                                                 FEarFul
                                                 avoiDant
Three Major Brain Systems Influencing
   Stimulus – Response Characteristics
   Brain System           Principal       Relevant Stimuli        Behavioral
(Related Personality     Monoamine                                Response
    Dimension)         Neuromodulator

Behavioral             Dopamine         Novelty                Exploratory
activation                                                     pursuit
(novelty seeking)                       Potential reward       Appetitive
                                                               approach
                                        Potential relief of    Active avoidance,
                                        monotony or            escape
                                        punishment
Behavioral inhibition Serotonin         Conditioned signals    Passive
(harm avoidance)                        for punishment,        avoidance,
                                        novelty, or            extinction
                                        frustrative
                                        nonreward
Behavioral             Norepinephrine   Conditioned signals    Resistance to
maintenance                             for reward or relief   extinction
(reward                                 of punishment
dependence)
Cloninger’s Seven-Factor Model
    Temperament Domains (Moderately heritable,
     not greatly influenced by family environment)
      a. Novelty Seeking

      b. Harm Avoidance

      c. Reward Dependence

      d. Persistence


2.      Character Domains (Moderately influenced
     by family environment, only weakly heritable)
      a. Self-transcendence

      b. Cooperativeness

      c. Self-directedness
DSM-IV Definition of Personality
                  Disorder
   An enduring pattern of inner experience and
    behavior that deviates markedly from the expectations
    of the individual’s culture. This pattern is manifested in
    two (or more) of the following areas:
         Cognition (i.e., ways of perceiving             and
          interpreting self, other people, and events)
         Affectivity (i.e., the range, intensity, ability,
          appropriateness of emotional response)
         Interpersonal functioning
         Impulse control
   The Enduring pattern is inflexible and pervasive
    across a broad range of personal and social situations.
DSM-IV Definition of Personality Disorder

C.    The enduring pattern leads to clinically significant
      distress or impairment in social, occupational, or
      other important areas of functioning.
     The pattern is stable and of long duration and its
      onset can be traced back at least to adolescence or
      early adulthood.
     The enduring pattern is not better accounted for as
      a manifestation or consequence of another mental
      disorder.
     The enduring pattern is not due to the direct
      physiological effects of a substance (e.g., a drug of
      abuse, a medication) or a general medical condition
      (e.g., head trauma).
Impulsive Disorders

Axis II
 Borderline Personality Disorder
 Antisocial Personality Disorder


Axis I
 Psychoactive Substance Use Disorder
 Bulimia
 Paraphilias
 Impulsive Control Disorder NEC
Levels of personality functioning
 Neurotic - stable, continuous, integrated
 identity, with mature and flexible defenses,
 good reality testing

 Borderline      -    unstable, inconsistent,
 discontinuous identity, primitive defenses,
 adequate reality testing

 Psychotic      -    fragmented,      confused,
 disorganised identity, primitive defenses, poor
 reality testing
Concepts of Borderline Disorders
BorDErlinE
schizophrEnia
(KEty)                        aFFEctivE
                                          atypical
(schizotypal schizophrEnia    DisorDErs
                                          aFFEctivE
pD - raDo,
                                          DisorDErs
mEEhl)
                                          (D.KlEin)


      BorDErlinE        BorDErlinE
     pErsonality       pErsonality
    organization         DisorDEr
     (KErnBErg)
                                              BorDErlinE
                                               synDromE
                                               (grinKEr)
                        nEurosE
                           s
Aspects of Levels of Personality Organization
                  Borderline             Neurotic             Normal
                  Organization           Orgaization          Orgaization
Identity          Incoherent sense       Coherent sense       Integrated sense
                  of self and            of self and          of self and
                  others; poor           others;              others;
                  investment in          investment in        investment in
                  work, leisure          work, leisure        work, leisure

Defenses          Use of primitive       Use of more        Use of more
                  defenses               advanced           advanced
                                         defenses; rigidity defenses;
                                                            flexibility
Reality testing   Variable empathy       Accurate             Accurate
                  with social            perception of        perception of
                  criteria of reality;   self vs, non-self    self vs, non-self
                  lack of subtle         internal vs          internal vs
                  tactfulness            external;            external;
                                         empathy with         empathy with
                                         social criteria of   social criteria of
                                         reality.             reality.
Aspects of Levels of Personality Organization

               Borderline       Neurotic        Normal
               Organization     Orgaization     Orgaization
Aggression     Self-directed    Inhibited       Anger
               aggression;      aggression;     modulated;
               some with        angry           appropriate
               aggression       outbursts       self-assertion
               toward others;   followed by
               hatred in        guilt
               severe cases
Internalized   Contradictory    Excessive        Stable,
values         value system;    guilt feelings; independent,
               incapacity to    some             individualized.
               live up to own   inflexibility in
               values,          dealing with
               significant      self
               absence of
               certain values
Aspects of Levels of Personality Organization


            Borderline          Neurotic          Normal
            Organization        Orgaization       Orgaization
Object      Troubled            Some degree       Lasting and
relations   interpersonal;      of sexual         deep relations
            absence of or       inhibition, or    with others;
            chaotic sexual      difficulties in   sexual
            relationships;      integrating sex   intimacy
            confused            with love; deep   combined
            internal working    relations with    with
            models of           other, with       tenderness;
            relationships;      specific          coherent
            severe              focused           working
            interference with   conflicts with    models of
            love relations      selected others   relationskips
stpD
                          mDD
                                Bip-ii
                  ptsD
 sEvErity   spD
 oF social
                                      aspD
DysFunction              BpD



             avpD               npD
                         hpD
Basic Beliefs and Strategies Associated with
         Traditional Personality Disorders
Personality    Basic                     Strategy (overt
Disorder       Beliefs/Attitudes         behavior)
Dependent      “I am helpless”           Attachment
Avoidant       “I may get hurt”          Avoidance
Passive-       “I could be controlled”   Resistance
Aggressive
Paranoid       “People are dangerous” Wariness
Narcissistic   “I am special”            Self-aggrandizement
Histrionic     “I need to impress”       Dramatics
Obsessive-     “I must not err”          Perfectionism
Compulsive
Antisocial     “Others are to be         Attack
Schizoid       taken” a plenty of
               “I need                   Isolation
               space”
Typical Overdeveloped and Underdeveloped Strategies
Personality        Overdeveloped                   Underdeveloped
Disorder
Obsessive-    Control- responsibility-           Spontaneity- playfulness
compulsive    systematization
Dependent     Help-seeking – clinging            Self-sufficiency
Passive-      Autonomy- resistance-              Intimacy- assertiveness-
aggressive    passivity- sabotage                activity- cooperativeness
Paranoid      Vigilance- mistrust-               Serenity- trust- acceptance
              suspiciousness
Narcissistic Self-aggrandizement-                Sharing- group identification
             competitiveness
Antisocial    Combativeness-                     Empathy- reciprocity- social
              exploitativeness- predation        sensitivity
Schizoid      Autonomy- isolation                Intimacy- reciprocity
Avoidant      Social vulnerability- avoidance-   Self-assertion
              inhibition
Histrionic    Exhibitionism- expressiveness-     Reflectionism- control-
              impressionism                      systematization
Borderline Personality Disorder
Epidemiology
 2 % of the general population
 Females 4 times the rate of males
 11 % of psychiatry outpatients
 25 % of acute psychiatry inpatients
 50 % of long term psychiatry inpatients
 60 % with co-existing Major Depressive
  Disorder
 7% complete suicide. ( 7 X General population)
 up to 75% attempt suicide
 69-80% self-mutilate
Interface with Health Care System
   Inpatient Psychiatric Units
       Top diagnosis for re-admissions to psych hospitals

   Emergency Rooms
       Cutting, burning, suicidal threats

   Intensive Care Units and medical inpatient units
       Overdoses and other sequelae of suicidal or parasuicidal
        behavior

   Outpatient primary care setting
       Psychosomatic complaints
       Doctor shopping
Borderline: On the “borderline” between
“neurosis” and “psychosis”
Not  an accurate term though – and not relevant
to current nosology
Current    trend is to call it “Emotional Intensity
Disorder”
Better   accepted by patients – more meaningful
Four Categories for Borderline
             Symptoms
   Poorly regulated emotions
       Mood swings and unstable emotions
       Anxiety
       Inappropriately intense anger
       Difficulty controlling anger
       Chronic feelings of emptiness

   Impulsivity
       Reckless behavior
       Suicidal behavior and self harm
       Munchausen’s Syndrome and by Proxy
       Suicide
Four Categories for Borderline
             Symptoms
   Impaired perception or reasoning
       Paranoid thinking
       Dissociative episodes
       Depersonalization
       Unstable self image or sense of self

   Markedly disturbed relationships
       Intense and unstable interpersonal relationships
       Black and white thinking
       Frantic efforts to avoid real or imagined
        abandonment
Can look like…..
   Schizophrenia
       hallucinations, illusions, paranoia

   Bipolar Affective Disorder
       mood lability and anger

   Major Depressive Disorder
       suicidal, depressed

   Antisocial Personality Disorder
       legal problems
Constituent Elements of Borderline
     Personality Organization (BPO)
   Patients with BPO are characterized by diffuse
    identity, the use of primitive defenses, generally
    intact yet fragile reality testing, impairments in
    affect regulation and in sexual and aggressive
    expression, inconsistent internalized values, and
    poor quality of relation with others.
   Clinically, the lack of integration of these internal
    representations of self and others becomes evident
    in the patient’s non-reflective, contradictory, or chaotic
    descriptions of self and others and in the inability to
    integrate or even to become aware of these
    contradictions.
   This lack of integration has a fundamental impact on
    the individual’s experience in the world.
Cluster B Personality Disorders and Development


                                           Development of
  Typical     Development of Borderline/   Antisocial/Narcissistic
Development      Histrionic Personality    Personality Disorders
                       Disorders




   self                  self                      self




                                                world and
 world and            world and
                                                 others
  others               others
Cluster B Personality Disorders and
               Development

  Development of             Development of
Borderline/Histrionic     Antisocial/Narcissistic
Personality Disorders     Personality Disorders




         self                       self




     world and                   world and
      others                      others
Constituent Elements of Borderline
     Personality Organization (BPO)
   Behavioral correlates of this borderline
    psychic structure include emotional lability,
    anger, interpersonal chaos, impulsive self-
    destructive behaviors, and proneness to
    lapses in reality testing.

   A typical specific manifestation in this diffuse
    and fragmented identity is the oscillation
    between helplessness and a rageful,
    tyrannical aggression directed toward oneself
    or others.
Constituent Elements of Borderline
     Personality Organization (BPO)
   Primitive defenses are organized around
    splitting, the radical separation of good and
    bad affects and of good and bad objects.
   These defense mechanisms represent
    attempts to protect an idealized segment of
    the individual psyche, or internal world, from
    an aggressive segment.
   This separation is maintained at the
    expense of integration of the images in the
    psyche.
Constituent Elements of Borderline
   Personality Organization (BPO)


                                 S+S-
                  S+S-
        O+O-

                         O+O-             O+O-



       O+O-       S+S-           S+S-


NORMAL ORGANIZATION
Consciousness of integration/complexity
Constituent Elements of Borderline
   Personality Organization (BPO)


                                 S-     S-
    S+          S+




                                O-
    O+                                 O-
                O+



SPLIT ORGANIZATION
Consciousness of all-good or all-bad
Constituent Elements of Borderline
   Personality Organization (BPO)

Reality Testing
 Individuals with BPO may lack subtle
  tactfulness in social interactions,
  particularly      under       stress.

 For example, under stress, those with
 BPO more easily regress to paranoid
 thinking.
Borderline Personality Disorder

            Etiology
Etiology
Multiple risk factors:
 Biological
       Temperament abnormalities (heritable)
       Decreased serotonin activity
   Psychological
       Trauma
       Emotional neglect
   Social
       Lack of support/emotional security
   Linehan’s theory – emotional invalidation
       Invalidating environment
Etiology of BPD
Type 1: Affective (Akiskal, Klein)
 **A    moderately heritable “subaffective”
  vulnerability, precipitated by environmental
  stress

Prototypic Criteria:
 #6: affective instability due to marked
  reactivity of mood (dysphoria or anxiety);
 #5: recurrent suicidal behavior, gestures or
  threats, or self-mutilating behavior
Etiology of BPD
Type 2: Impulsive (Zanarini, Hollander,
  Siever)
 **A moderately heritable impulse spectrum
  disorder, precipitated by environmental stress

Prototypic Criteria:
 #4: impulsivity in at least two areas that are
  potentially self-damaging;
 #5: recurrent suicidal behavior, gestures or
  threats, or self-mutilating behavior
Etiology of BPD
Type 3: Aggressive (Kernberg)
 **A primary moderately heritable aggressive
  temperament, or a secondary reaction to
  early trauma and/or abuse

Prototypic Criteria:
 #8: inappropriate, intense anger or difficulty
  controlling anger;
 #6: affective instability due to marked
  reactivity of mood (irritability)
Etiology of BPD
Type 4: Dependent (Masterson and Rinsley;
  Gunderson)
 **intolerance of aloneness, and impaired
  autonomy, possibly secondary to parental
  separation-resistance

Prototypic Criteria:
 #1: frantic efforts to avoid real or imagined
  abandonment;
 #6: affective instability due to marked
  reactivity of mood (anxiety)
Etiology of BPD

Type 5: Empty (Mahler; Adler and Buie)
 **failure to develop an evocative memory
  secondary to lack of empathy and
  inconsistency in early parenting

Prototypic Criteria:
 #7: chronic feelings of emptiness;
 #3: identity disturbance: markedly and
  persistently unstable self-image or sense of
  self
Genetic and Biological Factors
   Genetics a modest contributor of BPD Diagnosis but
    may be more salient for specific symptoms of BPD

   Reduced serotenergic activity in 5-HT system inhibits
    ability to modulate or control impulsive and aggressive
    behavior
      Differences b/w BPD and nonBPD patients in
       serotenergic functioning
      Repeated exposure to stress may blunt serotenergic
       activity (frequent increases in cortisol)
      Stress  frequent increases in cortisol  blunting of
       serotenergic activity  emotion dysregulation
      Limitations
          Lack of specificity for serotonin (i.e., MDD w/out
           impulsivity)
          Pharmacology targeting serotonin has limited
           efficacy in treating BPD
Neurobiology
Risk factors:
 Diminished serotonergic function in the
  prefrontal cortex
   Potential     biological risk factor for
    disinhibition,    impulsivity, and  affect
    dysregulation.

 Dysfunction   in the cortical-striatal-
 thalamic-frontal network
   behavioral   control
Frontolimbic Circuitry
 Prefrontal
           and limbic systems mediate
 the processing of and responses to
 emotional stimuli
Trauma
   Childhood Sexual Abuse (CSA)
       Historically considered a significant risk factor for
        BPD
       75% of patients with BPD have a hx of CSA but…
        only 90% of CSA victims have BPD

   Limitations
       Current evidence suggests that emotion
        dysregulation mediates the relationship between
        CSA and BPD
       Role of physical and emotional abuse which co-
        occurs with CSA?
Link with Childhood Trauma
 Many people with personality disorder report a
  history of childhood abuse or neglect
 Children who are physically abused, sexually
  abused, or neglected are significantly more
  likely to develop a PD as a young person
 Sexual abuse [usually with emotional
  abuse and neglect] is most strongly
  associated with BPD in particular
 In BPD, childhood trauma may still be affecting
  the individual as an adult, to an extent that
  impairs daily functioning
                Johnson JG et al. Arch General Psychiatry 1999
Family Interactions
 Neglect
 Emotional  uninvolvement
 Invalidation
Emotion Regulation
 “processby which individuals influence
 which emotions they have, when they
 have them, and how they experience
 and express these emotions.”
Emotion Dysregulation
   Vulnerability to negative emotion
       High sensitivity, reactivity, and slow return to
        baseline
       Influences emotional arousal
   Poor coping skills
       Inability to: manage social interactions, awareness
        of relevant stimuli, identify and label emotional
        experiences, manage arousal
   Maladaptive    responses               to     others
    expressions of emotion
       Wants, thoughts, goals. Others responses often
        trigger emotional arousal
Emotion Vulnerability
 Heightened  emotional sensitivity
 Emotion reactivity
 Slow return to baseline
Invalidation
 Validation
   Convey  legitimacy and acceptance of the
   other’s experience or behavior

 Invalidation
   Delegitimize
              valid experiences or fail to
   acknowledge their existence and/or
   legitimacy
Invalidating environment

Pervasively negates or dismisses
behavior independent of the actual
     validity of the behavior
Invalidating Family Environment
 Invalidation   of…
   Emotions,    thoughts, desires
   Over public behavior

   Difficult tasks, developmental milestones

   Sense of self and self initiated behavior
Risk Factors for Invalidation
 Unexpected  experience or behavior
 Behavior creates unwanted demands
 Caretaker has insufficient ability to help
  or understand
Invalidating responses -
          examples
- rejects self-description as inaccurate
- rejects response to events as incorrect or
     ineffective
- dismiss or disregard
- directly criticize or punish
- neglect
- pathologize normal responses
- reject response as attributable to socially
unacceptable characteristic
Linehan Biosocial Theory
Emotion Vulnerability                           Pervasive History of
                                                Invalidating Responses




                 Heightened Emotional Arousal



                    Inaccurate Expression
              (maladaptive behavioral responses)




                    Invalidating Responses

                                                   (Fruzzetti, Shenk, & Hoffman, 2005)
Linehan’s Diathesis-Stress theory: Etiology
       of borderline personality disorder




•Emotional dysregulation in child (diathesis) and a failure to
 validate the child’s feelings by the parents (stress) leads to a
 vicious cycle.
   –The emotional dysregulation may be inadvertently
     reinforced by parents if it becomes one of the only times the
     child receives parental attention.
Linehan’s Theory
 Emotional      invalidation:
   Emotionally     vulnerable  individual       +
   invalidating environment = BPD
   Limited opportunity to learn        to   label,
   understand or trust own feelings
   Looks   to others for how to cope
   Oscillatesbetween emotional inhibition to
   gain acceptance and emotional disinhibition
   to have feelings acknowledged
   Intermittent    reinforcement   =   emotional
   dysregulation
Consequences of Invalidation
 Heightened   emotional arousal
 Cognitive and attentional dysregulation
 Emotion skill deficits
 Secondary emotions
 Emotion dysregulation
 Passivity in problem solving
 Self-invalidation
 Social and interpersonal dysregulation
Borderline Personality
 Disorder Diagnosis – DSM-IV
A pervasive pattern of interpersonal
 relationships, self-image and affects,
 and marked impulsivity, beginning by
 early adulthood.

 Includesat least 5 of the following
 diagnostic criteria:
DSM IV - What is Borderline
            Personality Disorder ?
• 1. frantic efforts to avoid real or imagined
  abandonment.
•
Abandonment Issues
   The perception of impending separation or
    rejection, or the loss of external structure,
    can lead to profound changes in self-
    image, affect, cognition, and behavior.
    These individuals are very sensitive to
    environmental circumstances. They
    experience intense abandonment fears
    and inappropriate anger even when faced
    with a realistic time-limited separation or
    when there are unavoidable changes in
    plans, These abandonment fears are
    related to an intolerance of being alone
    and a need to have other people with
    them. Their frantic efforts to avoid
    abandonment may include impulsive
    actions such as self-mutilating or suicidal
    behaviors
Diagnostic Criteria - more
•   2. a pattern of unstable and intense
    interpersonal relationships
    characterized by alternating between
    extremes of idealization and
    devaluation
More……
3.. identity disturbance:
 markedly and persistently
 unstable self-image or sense of
 self
Identity Disturbance?
iDEntity DisturBancE – oFtEn DEscriBED as
“splitting”
From the book I Hate You, Don't Leave Me by Jerry Kreisman, M.D.
The world of a BP, like that of a child, is split into heroes and
villains. A child emotionally, the BP cannot tolerate human
inconsistencies and ambiguities; he cannot reconcile another’s
good and bad qualities into a constant coherent understanding
of another person. At any particular moment, one is either
Good or EVIL. There is no in-between; no gray area....people
are idolized one day; totally devalued and dismissed the next.
….Splitting is intended to shield the BP from a barrage of
contradictory feelings and images and from the anxiety of
trying to reconcile those images. But splitting often achieves
the opposite effect. The sense of his own identity and the
identity of others shifts even more dramatically and frequently
More DSM IV Criteria:

 4.   impulsivity in at least two areas
    that are potentially self-damaging
    (e.g., spending, sex, substance
    abuse, reckless driving, binge
    eating).


More DSM IV
5. recurrent suicidal behavior,
 gestures, or threats, or self-
 mutilating behavior
More…..
6. affective instability due to a marked
 reactivity of mood (e.g., intense
 episodic dysphoria, irritability, or anxiety
 usually lasting a few hours and only
 rarely more than a few days)
More DSM IV Criteria:
 7.   chronic feelings of emptiness
More…..
 8. inappropriate, intense anger or
  difficulty controlling anger (e.g.,
  frequent displays of temper, constant
  anger, recurrent physical fights)
 9. transient, stress-related paranoid
  ideation or severe dissociative
  symptoms
Miscellaneous attributes
 Bright,  funny, witty
 Problems with object constancy
 Difficulty in tolerating aloneness
 Chaotic lives
 Backgrounds of abuse
CAUTION!
   Everyone has all these traits to a certain
    extent. Especially teenagers. These traits
    must be long-standing (lasting years) and
    persistent. And they must be intense.

   Many people who have BPD also have other
    concerns, such as depression, eating
    disorders, substance abuse — even multiple
    personality disorder or attention deficit
    disorder. It can be difficult to isolate what is
    BPD and what might be something else.
BPD in Adolescents vs Adults
 Problems  with     diagnosing      BPD   in
 adolescents
   Pejorative
             label – stigmatizing
   May end up “growing out of it”

   Symptoms less stable in teens

   Can improve with treatment
The Course of BPD
 Usually  begins in adolescence
 80% women
 Severe, chronic
 1 in 10 suicide
 Impulsivity & emotional instability tend
  to decline over time
Co-Morbid Disorders
   Post traumatic stress disorder
   Mood disorders
   Panic/anxiety disorders
   Substance abuse (54% of BPs have a problem
    with substance abuse)
   Gender identity disorder
   Attention deficit disorder
   Eating disorders
   Multiple personality disorder
   Obsessive-compulsive disorder
Co-Morbid Disorders-               continued



   Highest incidence of co-morbid disorders:
    mood and anxiety disorders (including
    PTSD) *Gunderson (2001) study

   And… problems in managing mood and
    anxiety problems through dissociation,
    substance abuse, eating disorders.

   90-97% of BPD met criteria for other Axis II
    personality disorders (avoidant, paranoid
    and dependent were highest).
Borderline Personality Disorder
          Reorganized
 Emotional     dysregulation
  - affective instability
  - problems with anger
 Interpersonal     dysregulation
  - chaotic relationships
  - fears of abandonment
 Self   dysregulation
  - identity disturbance/difficulties
  - sense of emptiness
Borderline Personality Disorder
          Reorganized
 Behavioral    dysregulation
  - parasuicidal behavior
  - impulsivity
 Cognitive dysregulation
  - dissociative responses
  - paranoid ideation
“Living on the Edge”

Borderline Personality Disorder




        Dr. Bob Carey
        Regional Support Associates
The Inside Perspective –
Living on the Edge as a Borderline Personality

  Being a borderline feels like eternal hell. Nothing
  less. Pain, anger, confusion, hurt, never knowing
  how I'm gonna feel from one minute to the next.
  Hurting because I hurt those who I love. Feeling
  misunderstood. Analyzing everything. Nothing
  gives me pleasure. Once in a great while I will get
  "too happy" and then anxious because of that.
  Then I self-medicate with alcohol. Then I
  physically hurt myself. Then I feel guilty because
  of that. Shame. Wanting to die but not being able
  to kill myself because I'd feel too much guilt for
  those I'd hurt, and then feeling angry about that
  so I cut myself or O.D. to make all the feelings go
  away.”
Borderline PD in the Media
   Princess Diana?
Pharmacotherapy

B       Type 1     (Affective)
P       Type 2     (Impulsive)
D
        Type 3     (Aggressive)
T
y       Type 4     (Dependent)
p
e       Type 5     (Empty)


                 Psychotherapy
                                  96
Common Features of Recommended
     Psychotherapy for BPD
 Non-brief
 Strong therapeutic alliance
 Establishment of clear roles and
  responsibilities of patient and therapist

 Active therapist
 Hierarchy of priorities
Common Features of Recommended
     Psychotherapy for BPD

 Empathic validation + need for patient
  to control behavior

 Flexibility
 Concomitant individual and group
  approaches

 Boundary Setting
Common Features of Recommended
    Psychotherapy for BPD
   Monitor self-destructive & suicidal behaviours

   Manage own intense feelings

   Promote reflection rather than impulsive
    action

   Diminish splitting

   Set limits on individual’s self-destructive
    behaviour and, if necessary, convey the
    limitations of the therapists capacities
General tips for working with
people with BPD
 Regularly discuss person with your
 colleagues and supervisor

 Support   colleagues working with BPD
 clients

 Ensure    the person    gets    a
 comprehensive assessment; identify
 and manage co-morbid problems (eg.
 depression)
General tips for working with
people with BPD
 Focus on solving non-medical problems
 (eg. employment, budgeting, self care)
 Agree
      among colleagues on protocols for
 managing crises
 Become  familiar with guidelines      for
 managing anger or violent behaviour
 Recognise    your own limits for personal
 involvement
Boundaries
 Howdo these individuals push the
 boundaries?

 How   do you respond?
Splitting/boundaries
 Facilitate       communication      among
  providers
 Consider    altering treatment (e.g.,
  increasing        support,    seeking
  consultation)
 Be   explicit in establishing “boundaries”
 Maintain     consistency
 Avoid   boundary violations
Boundary Crossings
 Explore   the meaning of the boundary
 crossing
 Restate expectations about boundary
 and rationale
 Employ    limit-setting
 Making    exceptions to the usual
 boundaries may signal need for
 consultation or supervision
The Effectiveness of Psychodynamic Therapy
and Cognitive Behavior Therapy in the
Treatment of Personality Disorders: A Meta-
Analysis
   Both psychodynamic therapy and cognitive
    behavior therapy are effective treatments of
    personality disorders

   For psychodynamic therapy, the effect sizes
    indicate long-term rather than short-term
    change in personality disorders (mean follow-
    up period = 1.5 years [78 weeks] vs CBT
    mean follow-up = 13 weeks)
                        lEichsEnring F, lEiBing E, am J
                        psychiatry 2003; 160:1223-1232
Hierarchy of Priorities in Therapeutic Sessions
Dialectical Behavior Therapy    Psychoanalytic/Psychodynamic Therapies
       (Linehan 1993)            (Kernberg et al. 1989; Clarkin et al. 1999)

                                         Suicide or homicide threats
      Suicidal behaviors
                                     Overt threats to treatment continuity


     Therapy-interfering             Dishonesty or deliberate withholding
         behaviors
                                             Contract breaches

    Behaviors quality-of-life               In-session acting out
         interfering

                                         Between-session acting out


                                        Non-affective or trivial themes
thanK you

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New perspectives in borderline personality disorder

  • 1. Borderline Personality Disorder Prof. Amany Haroun El Rasheed Ain Shams Univ., Cairo, Egypt M.N.P., D.P.P., M.D. Master in Mental Hygiene (Johns Hopkins Univ.) Fellowship in Substance Abuse Treatment & Prevention (Johns Hopkins Univ.) APA Membership ISAM Membership WPA Fellowship FRC Psych
  • 2. What is a healthy personality?  SHORT FORMULA: ability to enjoy, to relate and to work.  Psychologically healthy with a positive development is a person who is able to utilize eight aspects or polarities – depending on life context or requirement – in a way that is situational or functional. (Fiedler)
  • 3. Eight Modalities of Personal Functioning  Individuality, Independence.  Relationship, Attachment, Security.  Spontaneity, Desire for New Experiences.  Stability, Self control.  Wellbeing, Pleasure.  Allowing and accepting pain, Melancholy  Actively structuring life − Manipulation.  Passive Receiving, letting things happen.
  • 4. Common Themes in Normality  strength of character  ability to experience  ability to learn from pleasure without experience conflict  ability to work  flexibility/ability to  ability to achieve adjust insight  ability to laugh  absence of  ability to love another symptoms/conflict  degree of acculturation
  • 5. Where is the line?  It’s all a matter of degree and which traits: e.g. To be a successful pilot, a person must have a degree of narcissism (healthy sense of self-confidence) and obsessive compulsive (attention to detail, conscientious).
  • 6. See the whole person  Therefore,don’t rely on a single, “slice- in-time” conclusion when considering traits  The most normal person can look pretty disordered at times when stressed
  • 7. Characteristics of Personality Disorders  An enduring pattern of inner experience and behavior that deviates markedly from the expectations of the individual’s culture,  is pervasive and inflexible,  has an onset in adolescence or early adulthood,  is stable over time,  and leads to distress or impairment.
  • 8. Personality Disorders: Facts and Statistics  Prevalence of Personality Disorders  About 0.5% to 2.5% of the general population  Rates are higher in inpatient and outpatient settings  Gender Distribution and Gender Bias in Diagnosis  Gender bias exists in the diagnosis of personality disorders  Such bias may be a result of criterion or assessment gender bias
  • 9. Personality Disorders: Facts and Statistics  Originsand Course of Personality Disorders  Thought to begin in childhood  Tend to run a chronic course if untreated  Co-Morbidity Rates are High (depression, anxiety)
  • 10. Personality Disorders: Facts and Statistics  Rates of personality disorder in the general population (Coid et al 2006) - 4-5% Rates of personality disorder in young adults, 24-25 years old (Moran et al 2006) – 18.6%  Rates of personality disorder among self- harm patients (Haw et al 2001) – 47%
  • 11. What is Personality?  Personality lies along a continuum from healthy to pathological  Itis founded on particular adaptations or arrests at various stages along the developmental path
  • 12. Character structures/personality traits  Result in distinct clusters of defenses, character structures, or personality traits  These persist over time, become internalised and repeat as scripts  They serve to assist us in managing anxiety and self-esteem
  • 13. Character structures/Personality Traits Enduring patterns of:  Perceiving  Relating to  Thinking about oneself and the environment  In a wide range of social and personal contexts
  • 14. Not accounted for by:  Culture  Religious beliefs  Immigration  Stressful events  Axis I disorders  Medical condition  Communication, autistic or developmental disorder
  • 15. Effects Two or more of the following:  Cognition  Affectivity  Interpersonal functioning  Impulse control
  • 16. Functional Assessment  Motivation - What is wished for, feared, valued?  Cognitive functioning - functioning, style, coherence, belief systems  Affective functioning - intensity, lability, experience of affect, capacity for ambivalence  Affect regulation - coping strategies, defenses, repertoire
  • 17. Functional Assessment  Experience of self - continuity, coherence, agent, self-esteem, ideals, self presentation, identity  Experience of others - wishes, fears, schemas  Capacity for relatedness  Management of aggression  Emotional developmental history
  • 18. When is personality pathological?  Where defenses become so rigid and inflexible that they are not adaptive  Reality is distorted  Psychological growth is prevented  NB These were adaptive in early life
  • 19. Personality Disorder Clusters  Personality disorders fall into three general clusters:  Persons in cluster A seem odd or eccentric  Paranoid, schizoid, schizotypal  Persons in cluster B seem dramatic, emotional or erratic  Antisocial, borderline, histrionic, narcissistic  Persons in cluster C appear as anxious or fearful  Avoidant, dependent, obsessive-compulsive
  • 20. Dimensions Dsm-iv: Emotional Cluster A – Odd or eccentric cluster (e.g., Dramatic paranoid, schizoid) Cluster B – Dramatic, emotional, erratic cluster (e.g., antisocial, borderline) Cluster C – Fearful or anxious cluster (e.g., avoidant, obsessive-compulsive) oDD ExcEntric anxious FEarFul avoiDant
  • 21. Three Major Brain Systems Influencing Stimulus – Response Characteristics Brain System Principal Relevant Stimuli Behavioral (Related Personality Monoamine Response Dimension) Neuromodulator Behavioral Dopamine Novelty Exploratory activation pursuit (novelty seeking) Potential reward Appetitive approach Potential relief of Active avoidance, monotony or escape punishment Behavioral inhibition Serotonin Conditioned signals Passive (harm avoidance) for punishment, avoidance, novelty, or extinction frustrative nonreward Behavioral Norepinephrine Conditioned signals Resistance to maintenance for reward or relief extinction (reward of punishment dependence)
  • 22. Cloninger’s Seven-Factor Model  Temperament Domains (Moderately heritable, not greatly influenced by family environment) a. Novelty Seeking b. Harm Avoidance c. Reward Dependence d. Persistence 2. Character Domains (Moderately influenced by family environment, only weakly heritable) a. Self-transcendence b. Cooperativeness c. Self-directedness
  • 23. DSM-IV Definition of Personality Disorder  An enduring pattern of inner experience and behavior that deviates markedly from the expectations of the individual’s culture. This pattern is manifested in two (or more) of the following areas:  Cognition (i.e., ways of perceiving and interpreting self, other people, and events)  Affectivity (i.e., the range, intensity, ability, appropriateness of emotional response)  Interpersonal functioning  Impulse control  The Enduring pattern is inflexible and pervasive across a broad range of personal and social situations.
  • 24. DSM-IV Definition of Personality Disorder C. The enduring pattern leads to clinically significant distress or impairment in social, occupational, or other important areas of functioning.  The pattern is stable and of long duration and its onset can be traced back at least to adolescence or early adulthood.  The enduring pattern is not better accounted for as a manifestation or consequence of another mental disorder.  The enduring pattern is not due to the direct physiological effects of a substance (e.g., a drug of abuse, a medication) or a general medical condition (e.g., head trauma).
  • 25. Impulsive Disorders Axis II  Borderline Personality Disorder  Antisocial Personality Disorder Axis I  Psychoactive Substance Use Disorder  Bulimia  Paraphilias  Impulsive Control Disorder NEC
  • 26. Levels of personality functioning  Neurotic - stable, continuous, integrated identity, with mature and flexible defenses, good reality testing  Borderline - unstable, inconsistent, discontinuous identity, primitive defenses, adequate reality testing  Psychotic - fragmented, confused, disorganised identity, primitive defenses, poor reality testing
  • 27. Concepts of Borderline Disorders BorDErlinE schizophrEnia (KEty) aFFEctivE atypical (schizotypal schizophrEnia DisorDErs aFFEctivE pD - raDo, DisorDErs mEEhl) (D.KlEin) BorDErlinE BorDErlinE pErsonality pErsonality organization DisorDEr (KErnBErg) BorDErlinE synDromE (grinKEr) nEurosE s
  • 28. Aspects of Levels of Personality Organization Borderline Neurotic Normal Organization Orgaization Orgaization Identity Incoherent sense Coherent sense Integrated sense of self and of self and of self and others; poor others; others; investment in investment in investment in work, leisure work, leisure work, leisure Defenses Use of primitive Use of more Use of more defenses advanced advanced defenses; rigidity defenses; flexibility Reality testing Variable empathy Accurate Accurate with social perception of perception of criteria of reality; self vs, non-self self vs, non-self lack of subtle internal vs internal vs tactfulness external; external; empathy with empathy with social criteria of social criteria of reality. reality.
  • 29. Aspects of Levels of Personality Organization Borderline Neurotic Normal Organization Orgaization Orgaization Aggression Self-directed Inhibited Anger aggression; aggression; modulated; some with angry appropriate aggression outbursts self-assertion toward others; followed by hatred in guilt severe cases Internalized Contradictory Excessive Stable, values value system; guilt feelings; independent, incapacity to some individualized. live up to own inflexibility in values, dealing with significant self absence of certain values
  • 30. Aspects of Levels of Personality Organization Borderline Neurotic Normal Organization Orgaization Orgaization Object Troubled Some degree Lasting and relations interpersonal; of sexual deep relations absence of or inhibition, or with others; chaotic sexual difficulties in sexual relationships; integrating sex intimacy confused with love; deep combined internal working relations with with models of other, with tenderness; relationships; specific coherent severe focused working interference with conflicts with models of love relations selected others relationskips
  • 31. stpD mDD Bip-ii ptsD sEvErity spD oF social aspD DysFunction BpD avpD npD hpD
  • 32. Basic Beliefs and Strategies Associated with Traditional Personality Disorders Personality Basic Strategy (overt Disorder Beliefs/Attitudes behavior) Dependent “I am helpless” Attachment Avoidant “I may get hurt” Avoidance Passive- “I could be controlled” Resistance Aggressive Paranoid “People are dangerous” Wariness Narcissistic “I am special” Self-aggrandizement Histrionic “I need to impress” Dramatics Obsessive- “I must not err” Perfectionism Compulsive Antisocial “Others are to be Attack Schizoid taken” a plenty of “I need Isolation space”
  • 33. Typical Overdeveloped and Underdeveloped Strategies Personality Overdeveloped Underdeveloped Disorder Obsessive- Control- responsibility- Spontaneity- playfulness compulsive systematization Dependent Help-seeking – clinging Self-sufficiency Passive- Autonomy- resistance- Intimacy- assertiveness- aggressive passivity- sabotage activity- cooperativeness Paranoid Vigilance- mistrust- Serenity- trust- acceptance suspiciousness Narcissistic Self-aggrandizement- Sharing- group identification competitiveness Antisocial Combativeness- Empathy- reciprocity- social exploitativeness- predation sensitivity Schizoid Autonomy- isolation Intimacy- reciprocity Avoidant Social vulnerability- avoidance- Self-assertion inhibition Histrionic Exhibitionism- expressiveness- Reflectionism- control- impressionism systematization
  • 35. Epidemiology  2 % of the general population  Females 4 times the rate of males  11 % of psychiatry outpatients  25 % of acute psychiatry inpatients  50 % of long term psychiatry inpatients  60 % with co-existing Major Depressive Disorder  7% complete suicide. ( 7 X General population)  up to 75% attempt suicide  69-80% self-mutilate
  • 36. Interface with Health Care System  Inpatient Psychiatric Units  Top diagnosis for re-admissions to psych hospitals  Emergency Rooms  Cutting, burning, suicidal threats  Intensive Care Units and medical inpatient units  Overdoses and other sequelae of suicidal or parasuicidal behavior  Outpatient primary care setting  Psychosomatic complaints  Doctor shopping
  • 37. Borderline: On the “borderline” between “neurosis” and “psychosis” Not an accurate term though – and not relevant to current nosology Current trend is to call it “Emotional Intensity Disorder” Better accepted by patients – more meaningful
  • 38. Four Categories for Borderline Symptoms  Poorly regulated emotions  Mood swings and unstable emotions  Anxiety  Inappropriately intense anger  Difficulty controlling anger  Chronic feelings of emptiness  Impulsivity  Reckless behavior  Suicidal behavior and self harm  Munchausen’s Syndrome and by Proxy  Suicide
  • 39. Four Categories for Borderline Symptoms  Impaired perception or reasoning  Paranoid thinking  Dissociative episodes  Depersonalization  Unstable self image or sense of self  Markedly disturbed relationships  Intense and unstable interpersonal relationships  Black and white thinking  Frantic efforts to avoid real or imagined abandonment
  • 40. Can look like…..  Schizophrenia  hallucinations, illusions, paranoia  Bipolar Affective Disorder  mood lability and anger  Major Depressive Disorder  suicidal, depressed  Antisocial Personality Disorder  legal problems
  • 41. Constituent Elements of Borderline Personality Organization (BPO)  Patients with BPO are characterized by diffuse identity, the use of primitive defenses, generally intact yet fragile reality testing, impairments in affect regulation and in sexual and aggressive expression, inconsistent internalized values, and poor quality of relation with others.  Clinically, the lack of integration of these internal representations of self and others becomes evident in the patient’s non-reflective, contradictory, or chaotic descriptions of self and others and in the inability to integrate or even to become aware of these contradictions.  This lack of integration has a fundamental impact on the individual’s experience in the world.
  • 42. Cluster B Personality Disorders and Development Development of Typical Development of Borderline/ Antisocial/Narcissistic Development Histrionic Personality Personality Disorders Disorders self self self world and world and world and others others others
  • 43. Cluster B Personality Disorders and Development Development of Development of Borderline/Histrionic Antisocial/Narcissistic Personality Disorders Personality Disorders self self world and world and others others
  • 44. Constituent Elements of Borderline Personality Organization (BPO)  Behavioral correlates of this borderline psychic structure include emotional lability, anger, interpersonal chaos, impulsive self- destructive behaviors, and proneness to lapses in reality testing.  A typical specific manifestation in this diffuse and fragmented identity is the oscillation between helplessness and a rageful, tyrannical aggression directed toward oneself or others.
  • 45. Constituent Elements of Borderline Personality Organization (BPO)  Primitive defenses are organized around splitting, the radical separation of good and bad affects and of good and bad objects.  These defense mechanisms represent attempts to protect an idealized segment of the individual psyche, or internal world, from an aggressive segment.  This separation is maintained at the expense of integration of the images in the psyche.
  • 46. Constituent Elements of Borderline Personality Organization (BPO) S+S- S+S- O+O- O+O- O+O- O+O- S+S- S+S- NORMAL ORGANIZATION Consciousness of integration/complexity
  • 47. Constituent Elements of Borderline Personality Organization (BPO) S- S- S+ S+ O- O+ O- O+ SPLIT ORGANIZATION Consciousness of all-good or all-bad
  • 48. Constituent Elements of Borderline Personality Organization (BPO) Reality Testing  Individuals with BPO may lack subtle tactfulness in social interactions, particularly under stress.  For example, under stress, those with BPO more easily regress to paranoid thinking.
  • 50. Etiology Multiple risk factors:  Biological  Temperament abnormalities (heritable)  Decreased serotonin activity  Psychological  Trauma  Emotional neglect  Social  Lack of support/emotional security  Linehan’s theory – emotional invalidation  Invalidating environment
  • 51. Etiology of BPD Type 1: Affective (Akiskal, Klein)  **A moderately heritable “subaffective” vulnerability, precipitated by environmental stress Prototypic Criteria:  #6: affective instability due to marked reactivity of mood (dysphoria or anxiety);  #5: recurrent suicidal behavior, gestures or threats, or self-mutilating behavior
  • 52. Etiology of BPD Type 2: Impulsive (Zanarini, Hollander, Siever)  **A moderately heritable impulse spectrum disorder, precipitated by environmental stress Prototypic Criteria:  #4: impulsivity in at least two areas that are potentially self-damaging;  #5: recurrent suicidal behavior, gestures or threats, or self-mutilating behavior
  • 53. Etiology of BPD Type 3: Aggressive (Kernberg)  **A primary moderately heritable aggressive temperament, or a secondary reaction to early trauma and/or abuse Prototypic Criteria:  #8: inappropriate, intense anger or difficulty controlling anger;  #6: affective instability due to marked reactivity of mood (irritability)
  • 54. Etiology of BPD Type 4: Dependent (Masterson and Rinsley; Gunderson)  **intolerance of aloneness, and impaired autonomy, possibly secondary to parental separation-resistance Prototypic Criteria:  #1: frantic efforts to avoid real or imagined abandonment;  #6: affective instability due to marked reactivity of mood (anxiety)
  • 55. Etiology of BPD Type 5: Empty (Mahler; Adler and Buie)  **failure to develop an evocative memory secondary to lack of empathy and inconsistency in early parenting Prototypic Criteria:  #7: chronic feelings of emptiness;  #3: identity disturbance: markedly and persistently unstable self-image or sense of self
  • 56. Genetic and Biological Factors  Genetics a modest contributor of BPD Diagnosis but may be more salient for specific symptoms of BPD  Reduced serotenergic activity in 5-HT system inhibits ability to modulate or control impulsive and aggressive behavior  Differences b/w BPD and nonBPD patients in serotenergic functioning  Repeated exposure to stress may blunt serotenergic activity (frequent increases in cortisol)  Stress  frequent increases in cortisol  blunting of serotenergic activity  emotion dysregulation  Limitations  Lack of specificity for serotonin (i.e., MDD w/out impulsivity)  Pharmacology targeting serotonin has limited efficacy in treating BPD
  • 57. Neurobiology Risk factors:  Diminished serotonergic function in the prefrontal cortex  Potential biological risk factor for disinhibition, impulsivity, and affect dysregulation.  Dysfunction in the cortical-striatal- thalamic-frontal network  behavioral control
  • 58. Frontolimbic Circuitry  Prefrontal and limbic systems mediate the processing of and responses to emotional stimuli
  • 59. Trauma  Childhood Sexual Abuse (CSA)  Historically considered a significant risk factor for BPD  75% of patients with BPD have a hx of CSA but… only 90% of CSA victims have BPD  Limitations  Current evidence suggests that emotion dysregulation mediates the relationship between CSA and BPD  Role of physical and emotional abuse which co- occurs with CSA?
  • 60. Link with Childhood Trauma  Many people with personality disorder report a history of childhood abuse or neglect  Children who are physically abused, sexually abused, or neglected are significantly more likely to develop a PD as a young person  Sexual abuse [usually with emotional abuse and neglect] is most strongly associated with BPD in particular  In BPD, childhood trauma may still be affecting the individual as an adult, to an extent that impairs daily functioning Johnson JG et al. Arch General Psychiatry 1999
  • 61. Family Interactions  Neglect  Emotional uninvolvement  Invalidation
  • 62. Emotion Regulation  “processby which individuals influence which emotions they have, when they have them, and how they experience and express these emotions.”
  • 63. Emotion Dysregulation  Vulnerability to negative emotion  High sensitivity, reactivity, and slow return to baseline  Influences emotional arousal  Poor coping skills  Inability to: manage social interactions, awareness of relevant stimuli, identify and label emotional experiences, manage arousal  Maladaptive responses to others expressions of emotion  Wants, thoughts, goals. Others responses often trigger emotional arousal
  • 64. Emotion Vulnerability  Heightened emotional sensitivity  Emotion reactivity  Slow return to baseline
  • 65. Invalidation  Validation  Convey legitimacy and acceptance of the other’s experience or behavior  Invalidation  Delegitimize valid experiences or fail to acknowledge their existence and/or legitimacy
  • 66. Invalidating environment Pervasively negates or dismisses behavior independent of the actual validity of the behavior
  • 67. Invalidating Family Environment  Invalidation of…  Emotions, thoughts, desires  Over public behavior  Difficult tasks, developmental milestones  Sense of self and self initiated behavior
  • 68. Risk Factors for Invalidation  Unexpected experience or behavior  Behavior creates unwanted demands  Caretaker has insufficient ability to help or understand
  • 69. Invalidating responses - examples - rejects self-description as inaccurate - rejects response to events as incorrect or ineffective - dismiss or disregard - directly criticize or punish - neglect - pathologize normal responses - reject response as attributable to socially unacceptable characteristic
  • 70. Linehan Biosocial Theory Emotion Vulnerability Pervasive History of Invalidating Responses Heightened Emotional Arousal Inaccurate Expression (maladaptive behavioral responses) Invalidating Responses (Fruzzetti, Shenk, & Hoffman, 2005)
  • 71. Linehan’s Diathesis-Stress theory: Etiology of borderline personality disorder •Emotional dysregulation in child (diathesis) and a failure to validate the child’s feelings by the parents (stress) leads to a vicious cycle. –The emotional dysregulation may be inadvertently reinforced by parents if it becomes one of the only times the child receives parental attention.
  • 72. Linehan’s Theory  Emotional invalidation:  Emotionally vulnerable individual + invalidating environment = BPD  Limited opportunity to learn to label, understand or trust own feelings  Looks to others for how to cope  Oscillatesbetween emotional inhibition to gain acceptance and emotional disinhibition to have feelings acknowledged  Intermittent reinforcement = emotional dysregulation
  • 73. Consequences of Invalidation  Heightened emotional arousal  Cognitive and attentional dysregulation  Emotion skill deficits  Secondary emotions  Emotion dysregulation  Passivity in problem solving  Self-invalidation  Social and interpersonal dysregulation
  • 74. Borderline Personality Disorder Diagnosis – DSM-IV A pervasive pattern of interpersonal relationships, self-image and affects, and marked impulsivity, beginning by early adulthood.  Includesat least 5 of the following diagnostic criteria:
  • 75. DSM IV - What is Borderline Personality Disorder ? • 1. frantic efforts to avoid real or imagined abandonment. •
  • 76. Abandonment Issues  The perception of impending separation or rejection, or the loss of external structure, can lead to profound changes in self- image, affect, cognition, and behavior. These individuals are very sensitive to environmental circumstances. They experience intense abandonment fears and inappropriate anger even when faced with a realistic time-limited separation or when there are unavoidable changes in plans, These abandonment fears are related to an intolerance of being alone and a need to have other people with them. Their frantic efforts to avoid abandonment may include impulsive actions such as self-mutilating or suicidal behaviors
  • 77. Diagnostic Criteria - more • 2. a pattern of unstable and intense interpersonal relationships characterized by alternating between extremes of idealization and devaluation
  • 78. More…… 3.. identity disturbance: markedly and persistently unstable self-image or sense of self
  • 79. Identity Disturbance? iDEntity DisturBancE – oFtEn DEscriBED as “splitting” From the book I Hate You, Don't Leave Me by Jerry Kreisman, M.D. The world of a BP, like that of a child, is split into heroes and villains. A child emotionally, the BP cannot tolerate human inconsistencies and ambiguities; he cannot reconcile another’s good and bad qualities into a constant coherent understanding of another person. At any particular moment, one is either Good or EVIL. There is no in-between; no gray area....people are idolized one day; totally devalued and dismissed the next. ….Splitting is intended to shield the BP from a barrage of contradictory feelings and images and from the anxiety of trying to reconcile those images. But splitting often achieves the opposite effect. The sense of his own identity and the identity of others shifts even more dramatically and frequently
  • 80. More DSM IV Criteria:  4. impulsivity in at least two areas that are potentially self-damaging (e.g., spending, sex, substance abuse, reckless driving, binge eating). 
  • 81. More DSM IV 5. recurrent suicidal behavior, gestures, or threats, or self- mutilating behavior
  • 82. More….. 6. affective instability due to a marked reactivity of mood (e.g., intense episodic dysphoria, irritability, or anxiety usually lasting a few hours and only rarely more than a few days)
  • 83. More DSM IV Criteria:  7. chronic feelings of emptiness
  • 84. More…..  8. inappropriate, intense anger or difficulty controlling anger (e.g., frequent displays of temper, constant anger, recurrent physical fights)  9. transient, stress-related paranoid ideation or severe dissociative symptoms
  • 85. Miscellaneous attributes  Bright, funny, witty  Problems with object constancy  Difficulty in tolerating aloneness  Chaotic lives  Backgrounds of abuse
  • 86. CAUTION!  Everyone has all these traits to a certain extent. Especially teenagers. These traits must be long-standing (lasting years) and persistent. And they must be intense.  Many people who have BPD also have other concerns, such as depression, eating disorders, substance abuse — even multiple personality disorder or attention deficit disorder. It can be difficult to isolate what is BPD and what might be something else.
  • 87. BPD in Adolescents vs Adults  Problems with diagnosing BPD in adolescents  Pejorative label – stigmatizing  May end up “growing out of it”  Symptoms less stable in teens  Can improve with treatment
  • 88. The Course of BPD  Usually begins in adolescence  80% women  Severe, chronic  1 in 10 suicide  Impulsivity & emotional instability tend to decline over time
  • 89. Co-Morbid Disorders  Post traumatic stress disorder  Mood disorders  Panic/anxiety disorders  Substance abuse (54% of BPs have a problem with substance abuse)  Gender identity disorder  Attention deficit disorder  Eating disorders  Multiple personality disorder  Obsessive-compulsive disorder
  • 90. Co-Morbid Disorders- continued  Highest incidence of co-morbid disorders: mood and anxiety disorders (including PTSD) *Gunderson (2001) study  And… problems in managing mood and anxiety problems through dissociation, substance abuse, eating disorders.  90-97% of BPD met criteria for other Axis II personality disorders (avoidant, paranoid and dependent were highest).
  • 91. Borderline Personality Disorder Reorganized  Emotional dysregulation - affective instability - problems with anger  Interpersonal dysregulation - chaotic relationships - fears of abandonment  Self dysregulation - identity disturbance/difficulties - sense of emptiness
  • 92. Borderline Personality Disorder Reorganized  Behavioral dysregulation - parasuicidal behavior - impulsivity  Cognitive dysregulation - dissociative responses - paranoid ideation
  • 93. “Living on the Edge” Borderline Personality Disorder Dr. Bob Carey Regional Support Associates
  • 94. The Inside Perspective – Living on the Edge as a Borderline Personality Being a borderline feels like eternal hell. Nothing less. Pain, anger, confusion, hurt, never knowing how I'm gonna feel from one minute to the next. Hurting because I hurt those who I love. Feeling misunderstood. Analyzing everything. Nothing gives me pleasure. Once in a great while I will get "too happy" and then anxious because of that. Then I self-medicate with alcohol. Then I physically hurt myself. Then I feel guilty because of that. Shame. Wanting to die but not being able to kill myself because I'd feel too much guilt for those I'd hurt, and then feeling angry about that so I cut myself or O.D. to make all the feelings go away.”
  • 95. Borderline PD in the Media  Princess Diana?
  • 96. Pharmacotherapy B Type 1 (Affective) P Type 2 (Impulsive) D Type 3 (Aggressive) T y Type 4 (Dependent) p e Type 5 (Empty) Psychotherapy 96
  • 97. Common Features of Recommended Psychotherapy for BPD  Non-brief  Strong therapeutic alliance  Establishment of clear roles and responsibilities of patient and therapist  Active therapist  Hierarchy of priorities
  • 98. Common Features of Recommended Psychotherapy for BPD  Empathic validation + need for patient to control behavior  Flexibility  Concomitant individual and group approaches  Boundary Setting
  • 99. Common Features of Recommended Psychotherapy for BPD  Monitor self-destructive & suicidal behaviours  Manage own intense feelings  Promote reflection rather than impulsive action  Diminish splitting  Set limits on individual’s self-destructive behaviour and, if necessary, convey the limitations of the therapists capacities
  • 100. General tips for working with people with BPD  Regularly discuss person with your colleagues and supervisor  Support colleagues working with BPD clients  Ensure the person gets a comprehensive assessment; identify and manage co-morbid problems (eg. depression)
  • 101. General tips for working with people with BPD  Focus on solving non-medical problems (eg. employment, budgeting, self care)  Agree among colleagues on protocols for managing crises  Become familiar with guidelines for managing anger or violent behaviour  Recognise your own limits for personal involvement
  • 102. Boundaries  Howdo these individuals push the boundaries?  How do you respond?
  • 103. Splitting/boundaries  Facilitate communication among providers  Consider altering treatment (e.g., increasing support, seeking consultation)  Be explicit in establishing “boundaries”  Maintain consistency  Avoid boundary violations
  • 104. Boundary Crossings  Explore the meaning of the boundary crossing  Restate expectations about boundary and rationale  Employ limit-setting  Making exceptions to the usual boundaries may signal need for consultation or supervision
  • 105. The Effectiveness of Psychodynamic Therapy and Cognitive Behavior Therapy in the Treatment of Personality Disorders: A Meta- Analysis  Both psychodynamic therapy and cognitive behavior therapy are effective treatments of personality disorders  For psychodynamic therapy, the effect sizes indicate long-term rather than short-term change in personality disorders (mean follow- up period = 1.5 years [78 weeks] vs CBT mean follow-up = 13 weeks) lEichsEnring F, lEiBing E, am J psychiatry 2003; 160:1223-1232
  • 106. Hierarchy of Priorities in Therapeutic Sessions Dialectical Behavior Therapy Psychoanalytic/Psychodynamic Therapies (Linehan 1993) (Kernberg et al. 1989; Clarkin et al. 1999) Suicide or homicide threats Suicidal behaviors Overt threats to treatment continuity Therapy-interfering Dishonesty or deliberate withholding behaviors Contract breaches Behaviors quality-of-life In-session acting out interfering Between-session acting out Non-affective or trivial themes

Editor's Notes

  1. Als psychisch gesund mit positiver Persönlichkeitsentwicklung wäre eine Person zu bezeichnen, die sich – je nach Lebenskontext und Lebensanforderung – aller acht Bedürfnisaspekte bzw. Polaritäten situationsspezifisch und funktional bedienen wird. (131) Zwei Zielkonstrukte: a) sozialbezogene Autonomie b) erfahrungsoffene Selbstsicherheit Therapeutische Vorschläge (Millon 1996): 1. Bringe die extremen Pole ins Gleichgewicht 2. Wirke den wiederholten dysfunktionalen Mustern entgegen 3. Ergreife praktische Schritte (Tactical Modalities) Das Gute, das ich tun will, tue ich nicht Take-Home-Messages 1. in uns allen schlummern Regungen und unerfüllte Wünsche, die uns oft nicht so reagieren lassen, wie wir möchten (Römer 7) 2. Nicht nur auf die Schwächen schauen – auch die Stärken sehen. 3. Anreichern der Persönlichkeit mit anderen Anteilen – welche Anteile möchte ich bei mir verstärken? 4. Wir leben nicht allein – persönliche Nische (Willi) – Spannungsfeld Person – Ideal – Umgebung – Realität. 5. Lernen Spannungen auszuhalten und eine persönliche Mitte finden. – hier vielleicht geistliche Ansätze.
  2. cognition - ways of perceiving and interpreting self, others and events affectivity - range, intensity, lability, appropriateness of emotional response
  3. Dynamics are not pathology An obsessive man organises his life around thinking, achieving self-esteem in areas such as scholarship, logical analysis, planning, decision making. A pathologically obsessive man ruminates unproductively, accomplishing no objective, realising no ambition, hating himself for going in circles. You can change economics, but not dynamics.
  4. Neurotic compulsive will be embarrassed to admit how often she washes the sheets. A borderline or psychotic woman will feel that anyone who washes them less often is unclean, or deficient in common sense or moral decency. Borderline - Primitive defenses, such as denial and splitting reduce reality testing in specific instances