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Haemopoiesis
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HAEMOPOIESIS GK MBASSA
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Pluripotential Stem Cell
Myeloid stem cell Lymphoid stem cell
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Myeloid stem cell
CFU-MEG CFU-E CFU-GM CFU-EOS CFU-BAS Megakaryocyte Rubriblast Monoblast Myeloblast Myeloblast Myeloblast Platelets Erythroblasts Monocyte/Macrophage Neutrophils Eosinophils Basophils
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Lymphoid stem cell
T- Cell precursors B- Cell precursors Lymphoblast Lymphoblast T-lymphocyte B-lymphocyte/plasma cell
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CFU-STEM BFU-E CFU-E
Rubriblast series Erythrocyte Erythropoietin low conc. Erythropoietin low conc. Erythropoietin high conc. Macrophage factor Cell-cell interaction, microenvironment, Burst forming activity, macrophage products, lymphocyte interleukin 1,2,3
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Progenitor cell Megakaryoblasts
Promegakaryocyte
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Ancestors and progenies
of haematopoietic cell series Recognizable cell series 1. Pluripotential Stem Cell 2. Unipotential stem cell 2. Unipotential stem cell 3. Myeloblast 4. Promyelocyte 5. Neutrophil myelocyte 6. Neutrophil metamyelocyte 7. Neutrophil stab cell (band) 8. NEUTROPHIL 3. Myeloblast 5. Eosinophil/Basophil myelocyte 8. EOSINOPHIL/BASOPHIL - 6. Eosinophil/Basophi metamyelocyte 7. Eosinophil/Basophi stab cell/band
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Recognizable cell series
1. Pluripotential Stem Cell 2. Unipotential stem cell 2. Unipotential stem cell 3. Megakaryoblast 4. Promegakaryocyte 5. Early megakaryocyte 6. Mature megakaryocyte 7. Productive megakaryocyte 8. PLATELET (Thrombocyte) 3. Monoblast 5. - 8. MONOCYTE 4.- 6. - 7. -
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Fig. 11: Human
bone marrow: Lymphocyte (a), mature neutrophil (b), normoblast (c), band neutrophil (d), normoblast (e), W-Giemsa x 400
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Fig. 11: Human
bone marrow: Neutrophilic, metamyelocytes (f, g), mature eosinophil (h), neutrophlic myelocyte (i), eosionophilic myelocyte (j), lymphocyte (k). W-Giemsa x 400
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Fig. 11: Human
bone marrow: Neutrophilic myelocyte (m, n), lymphocytes (o), late neutrophilic metamyelocyte (p), neutrophilic myelocyte (q), monocyte (r). W-Giemsa x 400
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