Kickstart Ventures' 2nd HealthTech Forum featured Julien de Salaberry, a globally-recognised expert on healthcare and technology. Julien, the Chief Innovation Officer and Founder of The Propell Group (based in Singapore), talked about healthcare trends in Southeast Asia and how “frugal innovation" can be done in healthcare delivery. And yeah, if you've got an interesting healthtech startup, message us at info@kickstart.ph. #‎startupPH‬

1. MEDTECH CONNECT Ÿ HealthTech Asia Investment Insights
30th June 2015 Ÿ Singapore Ÿ The Propell Group
INVESTMENT
Asia HealthTech
@enquirepropell
#HealthTech

2. ©2015 by The Propell Group - All rights reserved. Proprietary and Confidential.
• HealthTech innovation is disrupting healthcare and its established players
• Technology is driving a new paradigm to create better health care
• Developing markets can leapfrog their healthcare infrastructure limitations
• New opportunities are opening to shape the new paradigm
Healthcare is changing dramatically

3. ©2015 by The Propell Group - All rights reserved. Proprietary and Confidential.
• Data
• BioSensors
• Mobile Devices
• Frugal / Reverse Innovation
• 3D Printing
5 Key Drivers of HealthTech in Asia

4. ©2015 by The Propell Group - All rights reserved. Proprietary and Confidential.
Data: Changing Healthcare
Genomics
Next generation sequencing, data
management & analysis
Data Analytics
Data Analytics & Insights: working
with and mixing data sets
Public Awareness
Planning and Preventing: Using data
to reduce and prevent disease
Support Providers
Clinical and Non-clinical Intelligence:
Combining a greater variety of data
Digital Therapeutics
Patient Focused: Increase variety
and frequency of data
Health Eco-system
Collaboration: Pooling data from many
sources for bigger & better results

5. ©2015 by The Propell Group - All rights reserved. Proprietary and Confidential.
Biosensing Wearables: Creating Context
Activity
Trackers
e.g. Fitbit, Misfit
Smart
Watches
e.g. Garmin, Apple
Smart
Clothing
e.g. Athos
Patches &
Tattoos
e.g. Zio, MC10
Ingestibles &
Smart Implants
e.g. Proteus
BioSensors
Devices that convert a
biological element into a
signal output
Wearables
Are on- or in-body devices
that enable user
experience

6. ©2015 by The Propell Group - All rights reserved. Proprietary and Confidential.
Mobile Devices in Asia: Reaching Everyone
Source: Kleiner Perkins Caufield Byers

7. ©2015 by The Propell Group - All rights reserved. Proprietary and Confidential.
Micro sensor for long-term monitoring of cardiac
rhythms
Single-channel ECG recorder that is portable, easy
to use and low cost (FDA approved)
• Being rolled out across Apollo hospitals in India
Sophisticated physical exam:
tracks & trends vitals such as to, HR, VO2, ECG, BP
Flow monitor for safe and accurate infusion
• Y Combinator Accelerator graduate
Reverse Innovation: MedTech For All

8. ©2015 by The Propell Group - All rights reserved. Proprietary and Confidential.
LOW COST PROSTHETICS
Researchers at the University of Toronto, in
collaboration with Autodesk Research and CBM
Canada, used 3D printing to quickly produce
cheap and easily customizable prosthetic sockets
for patients in the developing world
TAILOR MADE SENSORS
Researchers have used scans of animal hearts to
create printed models, and then added stretchy
electronics on top of those models. The material
can be wrapped around the real heart and
enhanced the electronics with multiple sensors
3D Printing: Next Generation MedTech
BONE
Professor Susmita Bose of Washington State
University modified a 3D printer to bind
chemicals to a ceramic powder creating intricate
ceramic scaffolds that promote the growth of the
bone in any shape
HEART VALVES
Jonathan Butcher of Cornell University has
printed a heart valve that will soon be tested in
sheep. He used a combination of cells and
biomaterials to control the valve’s stiffness
MEDICAL EQUIPMENT
Dutch surgeons replaced the entire top of a 22
year–old woman’s skull with a customized printed
implant made from plastic
SKIN
James Yoo at the Wake Forest School of Medicine
in the US has developed a printer that can print
skin straight onto the wounds of burn victims.

9. “Investments in digital health are having a
positive impact and the momentum is likely
to continue and cause changes throughout
the entire healthcare ecosystem. In
particular, the pharmaceutical industry is
poised to take advantage of digital and
mobile innovation allowing them to “go
beyond the pill”
— Jack Young —
Head – Qualcomm Life Fund
Funding
TRENDS

10. ©2015 by The Propell Group - All rights reserved. Proprietary and Confidential.
• Key investment themes taking shape
• Venture capital funding doubled again
• Growing number of technology and strategic investors
• M&A deal flow growing
• Strong IPO trend
• 10,000+ DH startups across the globe
Significant activity in HealthTech funding

11. ©2015 by The Propell Group - All rights reserved. Proprietary and Confidential.
Venture funding of HealthTech: Growth outpaces other healthcare sectors
Health Sector Funding Changes
Based on total funding from 2012 and 2013
2013 vs 2012 2014 vs 2013
All Sectors Health Tech Med DevicesBiotech
9%
61%
29%
127%
10%
29%
-17%
21%

12. ©2015 by The Propell Group - All rights reserved. Proprietary and Confidential.
Venture funding of HealthTech: Key global trends
Top Trends of HealthTech Funding
2011 to 2014
Ranking 2011 2012 2013 2014
1
Healthcare Consumer
Engagement
Healthcare Consumer
Engagement
EHR & Clinical Workflow
Analytics & Big Data
Data aggregation & analysis to support a wide range of healthcare use
cases
2 Analytics & Big Data EHR & Clinical Workflow Analytics & Big Data
Healthcare Consumer Engagement
Consumer tools for the purchasing of healthcare services or health
insurance
3 Digital Dx
Personal Health Tools &
Tracking
Digital Medical Devices Digital Medical Devices
Software / hardware designed to treat a specific disease or condition
4 EHR & Clinical Workflow Care Coordination
Population Health
Management
Telemedicine
Delivery of healthcare services through virtual channels
5 Post-acute Solutions Wearables & Biosensing Wearables & Biosensing
Personal Medicine
Software to support the practice of medicine customised to an individual’s
genetics
6 Hospital Administration Telemedicine
Healthcare Consumer
Engagement
Population Health Management
Platforms for managing population health under the shift to risk-based
payment models

13. ©2015 by The Propell Group - All rights reserved. Proprietary and Confidential.
Acquisitions: Is this the start of the HealthTech sector maturing?
95 M&A Deals in 2014 - $20B
ACQUIRER TARGET
Flatiron Health Altos Solutions
Teladoc AmeriDoc
Evidera Archimedes
Optum Audax
Roche Bina Technologies
MDLive Breakthrough
Hearst Health CareinSync
Cambia Health ClarusHealth
Merck eCardio
Google Lift Labs
UnitedHealth Group MedSynergies
WellTok MindBloom
HCA PatientKeeper
Facebook ProtoGeo (Moves)
AirStrip Wireless Sense4Baby
MyFitnessPal Sessions
WebMD TheraSim
Covidien Zephyr Technologies
Sector # of M&A deals
Health Tech
Med Device
Payer
Biopharma
Provider
Other
Healthcare
Tech
Other
47
8
6
6
4
4
7
13
ACQUIRER TARGET VALUE
BD CareFusion $12.2B
Cognizant TriZetto $2.7B
Cerner Siemens Health $1.3B
Optum Alere $600M
Aetna bswift $400M
Brighton Health Privia $400M
GE API Healthcare $340M
Emdeon Change Healthcare $185M
Medtronic Corventis $150M
Astra Zeneca Definiens $150M
Intel Basis $100M
Everyday Health Medico.com $100M
Millenium Labs RxAnte $70M
St Jude Medical CardioMEMS $60M
Care.com Citrus Lane $49M
Advisory Board Co. HealthPost $25M
Weight Watchers Wello $9M
Premier Meddius $8M
DISCLOSED UNDISCLOSED

14. “For all emerging markets, the
conditions are very challenging. But
where we see challenges, I see
opportunity. In fact: our challenges
are your opportunities ”
— Joko Widodo —
President, Indonesia
Asia
PARADOXES

15. ©2015 by The Propell Group - All rights reserved. Proprietary and Confidential.
Asia Paradoxes: Infrastructure
Immature Healthcare Infrastructure
Health expenditure (%GDP) Health expenditure (per capita US$)
Nurses (per ‘000 population) Doctors (per’000 population)
3.5% 3.9% 4.6% 4.9%
9.0%
9.9%
11.0% 11.4%
16.9%
Kenya FranceBangla-
desh
India USJapan UKChina Ger-
many
19.50 44.10 44.50 164.50
3,445.90 3,590.80
4,524.10 4,973.10
7,830.10
FranceGer-
many
JapanUKChinaIndiaKenyaBangla-
desh
US
0.1
1.1 1.1 1.3
7.9 8.0 8.1
9.3
11.4
Ger-
many
JapanUSUKFranceIndiaKenyaChinaBangla-
desh
0.1
0.3
0.6
1.6
2.2 2.3
3.0
3.5
6.8
Ger-
many
FranceUSUKJapanChinaIndiaBangla-
desh
Kenya
Source: World Health Organisation, Espicom

16. ©2015 by The Propell Group - All rights reserved. Proprietary and Confidential.
Asia Paradoxes: Medical Needs
Large Unmet Medical Needs
Cardio Vascular Disease (Deaths per 100,000) Diabetes Disease (Deaths per 100,000)
Lung Cancer Disease (Death per 100,000) RTAs (Death per 100,000)
Indonesia AustraliaS.Korea China USIndia BangladeshSingapore France
Source: World Health Organisation,
34.7
79.7 82.4
150.8
165.8
203.7
29.2
60.3 68.8 80.5
UK Bangladesh FranceSingapore China USIndia IndonesiaS.Korea UK
10.8
13.4
23 23.8 23.8
29.5
5
8.1
9.9
15.2
Australia
S.Korea FranceIndia Bangladesh USSingapore ChinaIndonesia Australia
6.5
20.3 20.5
27.3 27.5
33.5
18.2
29.6 31
35.4
UK India FranceSingapore S.Korea USChina IndonesiaBangladesh UK
5.3
13.7
16.4
18.7
20.8
22.6
4.8
6.6 6.8
13.9
Australia

17. ©2015 by The Propell Group - All rights reserved. Proprietary and Confidential.
Asia Paradoxes: Income Diamond
Deeper Market Relevance
From skimming to penetrating the market
Premium Market
Segment
Value Market
Segment
Underserved
Market Segment
56%
30%
13%
1%

18. ©2015 by The Propell Group - All rights reserved. Proprietary and Confidential.
• Lifestyle and wellness apps driven by growing middle class affluence
• Infrastructure management and modernisation
• Chronic disease management driven by growing health awareness
• Reverse innovation enabling better care at an affordable price point
• Growing demand for senior healthcare products and services
Asia: Key Drivers

19. ©2015 by The Propell Group - All rights reserved. Proprietary and Confidential.
HealthTech: Asia HealthTech Startup Landscape
Nascent But Thriving Ecosystem
Note: WIP!
Source: Health Startups Asia!
HealthTech Startup Categories
Big Data &
Analytics
3%
Genomics &
Precision Medicine
2%
Consumer Health &
Wellness
18%
Navigating the
Healthcare System
19%
Patient
Engagement
23%
Practice
Engagement
16%
Sensors &
Diagnostics
15%
Telehealth &
Remote Monitoring
4%
HealthTech Startup Geographies
Australia
5%
Indonesia
3%
Singapore
7%
Malaysia
1%
Hong Kong
3%
India
29%
Philipines
2%
Vietnam
1%
China
43%
South Korea
1%
Thailand
1%
Japan
3%
Taiwan
1%

20. ©2015 by The Propell Group - All rights reserved. Proprietary and Confidential.
Venture funding of HealthTech: Asia Key Trends
Noteworthy Asia HealthTech Funding Rounds
Target Category
Funding Size
($M) & Stage
Principal
Investor(s)
Meet You (CH)
Consumer Health &
Wellness
35.0
Series C
• Matrix
Partners
• K2 Partners
Practo (INDIA)
Navigating The
Healthcare System
30.0
Series B
• Sequoia
Capital
PICOOC (CH)
Sensors &
Diagnostics
25.0
Series B
• Tencent
• Gobi Partners
1MG (pka HealthKartPlus)
(INDIA)
Navigating The
Healthcare System
20.0
Series B
• Sequoia
Capital
• Intel Capital
DocDoc (SG)
Navigating The
Healthcare System
8.5
Series A
• Jungle
Ventures
• SparkLabs
Target Category
Funding Size
($M) & Stage
Principal
Investor(s)
ConnexionsAsia (SG)
Consumer Health &
Wellness
8.0
Series A
• NorthStar
Investments
• BioVeda
Reka Health (SG)
Sensors &
Diagnostics
4.0
Series A
• Tembusu
Partners
Our Health Mate (SG)
Navigating The
Healthcare System
1.0
Seed / Pre A
• LeoTech
Healint (SG)
Patient Engagement 1.0
Seed / Pre A
• WaveMaker
• GREE
Ventures
mClinica (PH)
Patient Engagement 1.0
Seed / Pre A
• KickStart
Ventures
• 500Startups
Note: WIP!
Source: Health Startups Asia!

21. ©2015 by The Propell Group - All rights reserved. Proprietary and Confidential.
Asia Healthcare Accelerator Landscape
Most Asia accelerators have a broad sector focus
Next 12 months will likely see the launch of additional healthtech focused accelerators
• There are 100+ incubators &
accelerators across Asia –
virtually none are 100%
focused on healthtech
• Growing maturity of the
ecosystem vs. 115 healthtech
accelerators worldwide (87 in
the US)
• Putting Asia / Singapore on
the map
• Emergence of corporate
incubators with a healthtech
focus
Incubator! Accelerator!
Focused!
Broad!
Clearbridge
Accelerator
(SG)!
AIA !
(HK)!
MetLife
(SG)!
Independent!
Captive!
JFDI Asia
(SG)!
BioFactory
(SG)!
SPRING SSA
MedTech
(SG)1!
SparkLabs
(KR)!
rockstart!
(SG)!
Modern
Ageing!
(SG)3!
Muru D!
(SG)!
Other Asia
Accelerators2!
Note 1: Zicom MedTacc and Med Tech Alliance, together with SPRING Singapore will co-invest S$60 million to develop promising medical technology ventures!
Note 2: A number of accelerators exist in Asia e.g. GSF India which operate on a similar model to JFDI Asia but have no deliberate focus on healthtech!
Note 3: Modern Ageing is a pre-Accelerator!
EVA !
(IN)!

22. • HealthTech is disrupting healthcare and its stakeholders
• Technology is driving a new paradigm to create better healthcare
• Asia healthcare will be able to leapfrog its infrastructure limitations
• New opportunities are opening to shape the new paradigm
• What healthtech solution could you hack?
Healthcare is changing dramatically

23. Julien
de SALABERRY
Experienced regional head and GM. 15+
years in healthcare with leading brands
including Eli Lilly, Boston Scientific,
Baxter, GSK, Merck & Co. Significant Asia
Pacific Experience.
The Propell Group is a boutique venture
investor and adviser firm focused on
early stage companies in healthcare
technology
Co-Author of iDisrupted
Founder & CIO Ÿ The Propell Group
M: +65 9488 7334 Ÿ julien@propellgroup.biz
@enquirepropell