Masters of the Industry at OIS@AAO 2016. Moderated By: Jim Mazzo, Global President Ophthalmic Devices - Carl Zeiss Meditec Participants: Flemming Ornskov, MD, CEO - Shire Mike Ball, CEO - Alcon Ashley McEvoy, Company Group Chairman - Johnson & Johnson Vision Care William J. Link, PhD, Managing Director - Versant Ventures Ludwin Monz, PhD, President & CEO - Carl Zeiss Meditec William Meury, Chief Commercial Officer - Allergan Powered by: Healthegy For more ophthalmology innovation Visit us at www.ois.net

1. MASTERS OF THE INDUSTRY
Jim Mazzo
Carl Zeiss Meditec
Global President Ophthalmic Devices
OIS @ AAO 2016

2. Global Landscape
285M
people are visually impaired1
Reference:
1. Visual Impairment and Blindness Fact Sheet No. 282, World Health Organization,
http://www.who.int/mediacentre/factsheets/fs282/en/. Published August 2014. Accessed October 1, 2016.
80%
of all visual impairment can be
prevented or cured1

3. References:
1. 2015 Ophthalmic Diagnostic Equipment Market: Key Issues Shaping Diagnostic Market. Market Scope. 2015: 25-26.
2. 2015 Report on the Global Market for Dry Eye Products. Market Scope. 2015.
Global Eye Care Landscape
24M
Cataract
Surgeries
Annually1
337M
Dry Eye
Syndrome2
2.4B
Myopia1
676M
Hyperopia1

4. Reference:
1. 2015 Ophthalmic Diagnostic Equipment Market: Key Issues Shaping Diagnostic Market. Market Scope. 2015: 22, 24.
Global Eye Care Landscape
24M
DME1
22.3M
Advanced
AMD1
19M
Proliferative
Diabetic
Retinopathy1
72M
Glaucoma
(POAG + ACG)1

5. New Innovation Landscape
ReLEx®S
MILE
Xiidra™
Symfony®
AngioPlex™
Kamra™
Raindrop®I
nlay
Oculeve®
iStent®
InnFocus™
XEN®
CyPass®

6. Industry Landscape

7. Industry Landscape

8. Industry Landscape

9. Investment Landscape
Masters of the Industry 2016
$724BHealthcare M&A in 20151
$160BPfizer/Allergan second
largest M&A in history1
$16.7BU.S. medtech (device)
M&A in 20151
$2.73BU.S. medtech (device) venture
investments in 20151
Reference:
1. The MedTech Strategist, January 19, 2016; 3(1): 18, 19, 26.
9

10. Masters of the Industry 2016
Science is Changing
Big Data
10

11. Masters of the Industry 2016
Surgical Robotics
Science is Changing

12. Masters of the Industry 2016
Gene Therapy
Science is Changing

13. Masters of the Industry 2016
Bio Similars
Science is Changing

14. New Forces of Change
Masters of the Industry 2016

15. Innovation Landscape 2019
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16. 2016 Masters of the Industry
OIS @ AAO 2016
Mike Ball
CEO, Alcon
William Meury
Chief Commercial Officer,
Allergan
William J. Link, PhD
Managing Director,
Versant Ventures
Ashley McEvoy, Company
Group Chairman,
Johnson & Johnson Vision
Care
Ludwin Monz, PhD
President & CEO,
Carl Zeiss Meditec
Flemming Ornskov, MD
CEO, Shire