Cushing’s syndrome, also known as hypercortisolism is an endocrine disorder that occurs due to abnormally high levels of the hormone cortisol production in the body.

1. Cushing's Syndrome (CS) - Market Insights,
Epidemiology and Market Forecast-2027

2. Cushing’s Syndrome
CS
Cushing’s syndrome, also known as hypercortisolism is
an endocrine disorder that occurs due to abnormally
high levels of the hormone cortisol production in the
body.
Cushing’s Syndrome
Endogenous Cushing’s Syndrome
ACTH Dependent Cushing’s Syndrome (80-
85%)
ACTH Independent Cushing’s Syndrome (15-
20%)
Exogenous Cushing’s Syndrome
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3. Total Market Share Distribution of
Cushing’s Syndrome for 7 MM in 2015
US
Italy
France
Spain
UK
Germany
Japan
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4. Total Market Share Distribution Forecast of
Cushing’s Syndrome for 7 MM in 2027
US
Italy
France
Spain
UK
Germany
Japan
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5. Key Findings
The forecasted Total Market size of CS
for 2027 is $XXX.
First Line of Treatment includes
Surgery and Glucocorticoid
replacement and discontinuation.
Cushing’s syndrome isn’t inherited but
tendency to develop tumors of the
endocrine glands may have been
inherited which may lead to familial
cushing’s syndrome.
United States accounts for the highest
number of cases of Cushing’s
syndrome. A total of 20,110 prevalent
cases were diagnosed in 2015.
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6. Market Drivers
321
Rich Product Pipeline
Use of Combination Therapies
Increase in number of
prevalent pool
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7. Market Barriers
1
2
3
4
Lack of targeted
therapies
Current therapies available with
medicines are largely reserved for pre-
operative treatment or in cases where
the tumour cannot be located or
whenever a definitive treatment is
delayed. No available drug targets the
main cause and cures the disease.
Lack of methods for
early Diagnosis
Due to lack of methods for early
diagnosis patients lose the chances of
better treatment.
Lack of proper
treatment options
The first line of treatment for Cushing’s
Disease is Surgery. But many patients
do not achieve remission or they have
recurrences.
Pathophysiology
understanding
The Pathophysiology of Cushing’s
Syndrome is not well understood
especially in pediatrics. So it leads to
delays in diagnosis and tests used to
screen or confirm the diagnosis.
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8. Key Players in the Market
Corcept
Therapeutics
Novartis
Astorg Cortendo AB
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