Presentation from the 7th Penang International Halal Expo & Conference, 29 ~ 31 January 2016

1. Mark Sykes, Fera Science Limited
Enhancing Halal Sustainability through
Halal Research and Innovation

2. The largest and
longest serving
provider of agri-food
research, services and
regulatory advice in
the UK
The trusted provider
to governments and
the commercial sector

3. Meet the numbers, face the
challenge
 The world population will increase
by 2.4 billion by 2050 to 9.4 billion
 This population is expected to be
wealthier, eating more and
differently
 It is estimated that we will need to
produce between 60-110% more food
 It is estimated that 40% of global
production is lost to pests and
diseases

4. Working hard to meet the challenges
of food supply in the 21st Century
Delivered in partnership with government,
industry and society, globally
 Fera bridges the interests of
governments, the commercial
sector and the public
− Operating at the leading edge of
current and future needs
− Progressing evidence-based consensus
on issues of concern and sensitivity

5. Fera International & the fields
within which we work
 Crop protection & economic yield
potential
− Plant health diagnostics and pesticide
resistance
− Farmer practice / agri-dealer inputs database
 Food safety and quality, including
authenticity and fraud
− Pesticides, toxins and isotopes
− Food trade risk database products
 Land-use, farming stewardship and eco-
sustainability
− Land use, design and ecosystem services
− Eco-toxicity and fate of agri-chemicals

6. Crop protection and economic
yield potential
 Supporting pest prevention at
import borders and in fields
− Plant health capacity in pest risk
analysis, inspection and
diagnostics
− Monitoring field pest and diseases,
including mycotoxins
− Tracking emergence of new pests,
evolving virulence and pesticide
resistance
− Data bases for risk analysis
decision-making
− Training

7.  Providing assurance along the
food supply chain
− Food safety testing for
contaminants, pesticide residues
and microbials
− Food authenticity and detection
of fraud
− Knowledge products for
regulatory compliance
− Proficiency testing schemes for
analytical competence (Fapas®)
− Emerging risks to food supply and
procurement
− Training
Food quality, safety and
authenticity

8. Contract Laboratory
Cost-efficient, timely delivery,
customer focussed
National Institute – National Reference Laboratory
Representation at national and international level
R&D Institute
Applied R&D underpinning policy,
supporting NPD, delivering solutions
Food Quality, Safety and
Authenticity

9. Fapas® Proficiency Testing
Laboratory assurance
meeting the highest
standards
 Food Chemistry
 Food Microbiology
 GM Materials
 Water and Environmental
 Bespoke: tests to your
specifications
 Reference Materials
Fapas®
Operates via agencies in 43 countries
Participation greatly assists ISO17025
accreditation

10. Case study - Wood and source of origin
for ethical and sustainable production
 (EU) 995/2010) stipulates that importers of tropical timber must be able to
identify the origin of timber used in their products
 Since March 2013, it has been a criminal offence to sell endangered species
of timber in the European Union without a FLEGT licence
 Analysis of the light bio-elements of carbon, hydrogen, oxygen, and sulphur
offer the potential to reveal the country/ region of origin of timbers
 Chemical profiling and genetic analyses offer additional levels of
confirmation

11. Stewardship for Sustainable, Safe and
Ethical Crop Production Overseas/UK
The Fera 3SECP approach to bench marking sustainability
Sustainable, safe and ethical sourcing of food is increasingly critical to
brand value and rigorously assessed for scientific merit.
Fera is uniquely able to evidence the scientific outcomes that support the
needs of crop production chain stakeholders and a 3SECP standard.
 Production Economy
 Carbon Economy
 Nutritional Economy
 Ecosystem services Economy
 Water Economy
 Societal Economy

12. PT 19194, pesticide residues in tomato
112 registered participants from 32 countries
BRAZIL MOROCCO
CANARY ISLANDS NETHERLANDS
CHILE PANAMA
CHINA POLAND
COLOMBIA SINGAPORE
CYPRUS SOUTH AFRICA
EGYPT SPAIN
FRANCE SWITZERLAND
GERMANY TAIWAN
GREECE THAILAND
HONG KONG TURKEY
ITALY UGANDA
JORDAN UNITED ARAB EMIRATES
SOUTH KOREA UNITED KINGDOM
MALAYSIA USA
MEXICO VIETNAM
69
92
43
100
99
58
42
102
2
21
103
106
24
56
64
80
94
57
9
82
37
93
29
14
18
65
79
22
26
83
27
87
61
85
46
40
98
95
1
34
86
107
48
4
77
68
88
55
49
5
3
7
28
51
91
90
59
12
39
54
62
89
47
52
60
8
73
75
13
19
38
35
36
6
41
33
44.2 µg/kg
30.7 µg/kg
17.2 µg/kg
-5.0
-4.0
-3.0
-2.0
-1.0
0.0
1.0
2.0
3.0
4.0
5.0
6.0
7.0
8.0
z-score
Laboratory Number
Pyriproxifen z-score chart
Laboratory assurance
meeting the highest
standards
 Food chemistry
 Food microbiology
 GM Materials
 Water and environmental
 Bespoke: Tests to your
specifications
 Reference Materials
 ISO 17043 accredited
 Agents in 43 countries
Case study – Quality assurance and
Fapas® Proficiency Testing
0009

13. Economics of Food Sustainability
Melamine
Illegal vet drugs
Recycling oil

14. Halal Sustainability
What is scientifically possible to
determine?
What can Fera as learn from
this?
What projects can we initiate as
a result?

15. Scientific possibilities ?

16. Authenticity Proficiency Testing

17. Results of an authenticity PT
Analyte Assignment No. results
satisfactory
Total number
of results
%
satisfactory
beef present 41 41 100
chicken absent 39 41 95
pork present 42 44 95
Results of FAPAS PT 2959, lamb
Should we be concerned?
What was the contamination level?
What methods were being used?

18. Methods trends, DNA, non-DNA
2009
ELISA
PCR
2014
ELISA
PCR
2009
PCR accredited
PCR not
accredited
2014
PCR accredited
PCR not
accredited

19. Previous work at Fera
2007, bovine
2008, porcine

20. Proteomics and Gelatine
• Byproduct from the meat / fish industry
• High temperatures, acid/alkali treat in industry
• Collagen
Current research at Fera

21. Industrial production

22. Uses of Gelatine

23. Protein analysis
A = Alanine M=Methionine
C = Cysteine N=Asparagine
D= Aspartic acid P=Proline
E=glutamic acid Q=glutamine
F= Phenylalanine R =Arginine
G=glycine S=Serine
H=Histidine T=Threonine
I=Isoleucine V= Valine
K = Lysine W = Tryptophan
L=Leucine Y=Tyrosine
-CCTAUGGGUGAUGAAUUUAAACGAAAUUUAGCUAUUACUGUUUCUCCUCAACAUUAUUGU
Protein sequence
database
www.uniprot.org

24. Mass Spectrometry
Fragment ion spectrum of cow collagen peptide :
GETGPAGPAGPIGPVGAR (precursor mass 1560.8064)
Fragment ion spectrum of complementary pig sequence :
GETGPAGPAGPVGPVGAR (precursor mass 1546.7915)

25. On-going development
Determine the species origin of gelatine in foods
• Mass spectrometry method
• Screen for species-specific peptides from a proprietary database
• Matrices: gelatine, desserts, confectionery, processed meats,
capsules, injection mixes and meat exudate…
• Reporting limit – matrix specific, aim for 0.4-1.0%

26. What do we do next?
• Continue food monitoring programmes
• Increase accreditation and certification
• Understand laboratory capability
• Expand associated quality assurance
• Develop appropriate proficiency tests
• Develop appropriate reference materials
• Collaborate with the official bodies
Fera
Enhancing Halal Sustainability through Halal
Research and Development

27. Acknowledgements
YB Dato’ Haji Abdul Malik Kassim
PIHH Secretariat
Joseph Chan, TMS Malaysia
Fera Colleagues
Helen Grundy
Andrew Swift
Kate Somerwill
© Copyright Fera Science Limited